| GILDGILEAD SCIENCES, INC. | 1,089,033 | $151.8M |
| REGNREGENERON PHARMACEUTICALS, INC. | 89,974 | $69.5M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 112,718 | $37.3M |
| INSMINSMED Inc | 180,405 | $29.5M |
| MRNAModerna, Inc. | 302,114 | $15.3M |
| RVMDREVOLUTION MEDICINES, INC. | 144,882 | $14.1M |
| INCYIncyte Corp. | 149,611 | $14.1M |
| EXELEXELIXIS, INC. | 270,598 | $11.6M |
| IONSIONIS PHARMACEUTICALS INC | 135,878 | $10.2M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 162,368 | $9.2M |
| ROIVRoivant Sciences Ltd. | 325,757 | $9.0M |
| JAZZJazz Pharmaceuticals plc | 38,508 | $7.3M |
| APLSApellis Pharmaceuticals, Inc. | 96,125 | $3.9M |
| VKTXViking Therapeutics, Inc. | 95,034 | $3.1M |
| ACADACADIA PHARMACEUTICALS INC | 128,689 | $2.9M |
| BBIOBridgeBio Pharma, Inc. | 33,388 | $2.5M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 40,322 | $2.1M |
| TEVATeva Pharmaceutical Industries Limited | 63,829 | $1.9M |
| CYTKCYTOKINETICS INC | 28,486 | $1.9M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 29,649 | $1.9M |
| SMMTSummit Therapeutics Inc. | 96,009 | $1.8M |
| PBYIPUMA BIOTECHNOLOGY, INC. | 272,890 | $1.7M |
| PTGXProtagonist Therapeutics, Inc | 16,303 | $1.7M |
| PCVXVaxcyte, Inc. | 28,102 | $1.6M |
| AXSMAxsome Therapeutics, Inc. | 9,064 | $1.5M |
| NUVLNuvalent, Inc. | 14,317 | $1.5M |
| PTCTPTC THERAPEUTICS, INC. | 20,211 | $1.4M |
| OGNOrganon & Co. | 225,178 | $1.3M |
| FOLDAMICUS THERAPEUTICS, INC. | 88,119 | $1.3M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 14,650 | $1.3M |
| TGTXTG THERAPEUTICS, INC. | 37,685 | $1.3M |
| TERNTerns Pharmaceuticals, Inc. | 20,516 | $1.1M |
| COGTCogent Biosciences, Inc. | 27,707 | $1.1M |
| SRRKScholar Rock Holding Corp | 19,747 | $971K |
| APGEApogee Therapeutics, Inc. | 9,350 | $787K |
| LGNDLigand Pharmaceuticals Incorporated | 3,805 | $760K |
| DNTHDianthus Therapeutics, Inc. /DE/ | 8,591 | $721K |
| ADMAADMA BIOLOGICS, INC. | 78,823 | $710K |
| SIGASIGA TECHNOLOGIES INC | 131,626 | $704K |
| SYRESpyre Therapeutics, Inc. | 13,905 | $701K |
| DNLIDenali Therapeutics Inc. | 34,168 | $656K |
| TVTXTravere Therapeutics, Inc. | 20,785 | $618K |
| KODKodiak Sciences Inc. | 15,103 | $576K |
| BEAMBeam Therapeutics Inc. | 23,870 | $569K |
| IRONDisc Medicine, Inc. | 8,704 | $557K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 15,847 | $536K |
| LQDALiquidia Corp | 13,680 | $516K |
| ADPTAdaptive Biotechnologies Corp | 35,558 | $494K |
| ARQTArcutis Biotherapeutics, Inc. | 20,547 | $484K |
| CLDXCelldex Therapeutics, Inc. | 14,537 | $461K |
| TNGXTango Therapeutics, Inc. | 21,051 | $440K |
| VCELVericel Corp | 13,599 | $437K |
| INVAInnoviva, Inc. | 17,702 | $412K |
| ELVNEnliven Therapeutics, Inc. | 10,480 | $411K |
| NTLAIntellia Therapeutics, Inc. | 31,268 | $401K |
| IMVTImmunovant, Inc. | 15,774 | $392K |
| ZYMEZymeworks Inc. | 15,340 | $384K |
| DAWNDay One Biopharmaceuticals, Inc. | 17,880 | $383K |
| ARDXARDELYX, INC. | 60,780 | $364K |
| ORKAOruka Therapeutics, Inc. | 6,687 | $328K |
| RCUSArcus Biosciences, Inc. | 15,072 | $326K |
| ANIPANI PHARMACEUTICALS INC | 3,995 | $307K |
| ANABANAPTYSBIO, INC | 5,526 | $306K |
| SLNOSOLENO THERAPEUTICS INC | 9,041 | $303K |
| ALMSALUMIS INC. | 13,604 | $300K |
| STOKStoke Therapeutics, Inc. | 9,089 | $296K |
| HROWHARROW, INC. | 8,360 | $295K |
| IBRXImmunityBio, Inc. | 37,521 | $288K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 9,239 | $281K |
| NRIXNurix Therapeutics, Inc. | 17,611 | $273K |
| OCULOCULAR THERAPEUTIX, INC | 31,418 | $266K |
| RLAYRelay Therapeutics, Inc. | 25,807 | $257K |
| VRDNViridian Therapeutics, Inc.\DE | 12,080 | $236K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 65,451 | $230K |
| XERSXeris Biopharma Holdings, Inc. | 37,970 | $220K |
| GERNGERON CORP | 142,122 | $212K |
| OPKOPKO HEALTH, INC. | 176,260 | $201K |
| KURAKura Oncology, Inc. | 22,684 | $184K |
| ARVNARVINAS, INC. | 16,930 | $179K |
| NUVBNuvation Bio Inc. | 41,690 | $179K |
| ABUSArbutus Biopharma Corp | 35,820 | $161K |
| BHVNBiohaven Ltd. | 18,006 | $152K |
| PRTAPROTHENA CORP PUBLIC LTD CO | 15,386 | $150K |
| ORICOric Pharmaceuticals, Inc. | 11,310 | $143K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 45,810 | $141K |
| RGNXREGENXBIO Inc. | 11,615 | $97K |
| SANASana Biotechnology, Inc. | 26,678 | $77K |
| AVXLANAVEX LIFE SCIENCES CORP. | 20,345 | $62K |