| FOLDAMICUS THERAPEUTICS, INC. | 1,757,899 | $25.4M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 71,767 | $23.7M |
| PTCTPTC THERAPEUTICS, INC. | 318,405 | $21.7M |
| ANIPANI PHARMACEUTICALS INC | 185,629 | $14.3M |
| JAZZJazz Pharmaceuticals plc | 62,142 | $11.7M |
| INSMINSMED Inc | 56,056 | $9.2M |
| TERNTerns Pharmaceuticals, Inc. | 165,725 | $8.7M |
| ELVNEnliven Therapeutics, Inc. | 218,867 | $8.6M |
| GPCRStructure Therapeutics Inc. | 165,426 | $8.0M |
| CNTACentessa Pharmaceuticals plc | 171,933 | $6.8M |
| AGIOAGIOS PHARMACEUTICALS, INC. | 200,061 | $6.8M |
| CYTKCYTOKINETICS INC | 101,565 | $6.7M |
| KALVKalVista Pharmaceuticals, Inc. | 315,537 | $6.4M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 73,468 | $6.2M |
| CMPXCompass Therapeutics, Inc. | 1,076,004 | $5.7M |
| APLSApellis Pharmaceuticals, Inc. | 123,824 | $5.0M |
| COGTCogent Biosciences, Inc. | 112,463 | $4.3M |
| RCUSArcus Biosciences, Inc. | 193,561 | $4.2M |
| ADPTAdaptive Biotechnologies Corp | 262,199 | $3.6M |
| ASMBASSEMBLY BIOSCIENCES, INC. | 120,500 | $3.3M |
| ADMAADMA BIOLOGICS, INC. | 330,148 | $3.0M |
| TNGXTango Therapeutics, Inc. | 120,689 | $2.5M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 48,765 | $2.5M |
| RNAAtrium Therapeutics Inc. | 162,759 | $2.2M |
| KNSAKiniksa Pharmaceuticals International, plc | 43,599 | $2.1M |
| APGEApogee Therapeutics, Inc. | 23,088 | $1.9M |
| HRMYHarmony Biosciences Holdings, Inc. | 68,116 | $1.9M |
| XERSXeris Biopharma Holdings, Inc. | 296,431 | $1.7M |
| STOKStoke Therapeutics, Inc. | 49,302 | $1.6M |
| ABVXAbivax SA | 14,313 | $1.6M |
| ROIVRoivant Sciences Ltd. | 53,888 | $1.5M |
| UPBUpstream Bio, Inc. | 161,349 | $1.5M |
| ABSIAbsci Corporation | 332,263 | $997K |
| FDMT4D Molecular Therapeutics, Inc. | 101,110 | $941K |
| KODKodiak Sciences Inc. | 22,152 | $844K |
| IMVTImmunovant, Inc. | 33,553 | $833K |
| QUREuniQure N.V. | 48,824 | $798K |
| MRNAModerna, Inc. | 15,691 | $797K |
| LQDALiquidia Corp | 20,551 | $776K |
| ANNXAnnexon, Inc. | 123,282 | $683K |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 10,002 | $627K |
| NKTRNEKTAR THERAPEUTICS | 8,063 | $580K |
| CMPSCOMPASS Pathways plc | 102,828 | $569K |
| MLTXMoonLake Immunotherapeutics | 28,682 | $535K |
| PGENPRECIGEN, INC. | 135,753 | $525K |
| ABCLAbCellera Biologics Inc. | 141,295 | $493K |
| OVIDOvid Therapeutics Inc. | 212,211 | $471K |
| SMMTSummit Therapeutics Inc. | 22,505 | $427K |
| GMABGenmab A/S | 13,467 | $361K |
| LENZLENZ Therapeutics, Inc. | 39,285 | $359K |
| ZBIOZenas BioPharma, Inc. | 17,638 | $345K |
| TLXTelix Pharmaceuticals Limited | 34,873 | $334K |
| CTMXCytomX Therapeutics, Inc. | 67,732 | $318K |
| OGNOrganon & Co. | 52,525 | $315K |
| NUVLNuvalent, Inc. | 2,945 | $302K |
| DMRADamora Therapeutics, Inc. | 10,824 | $280K |
| ATAIAtai Beckley N.V. | 77,611 | $275K |
| SPRYARS Pharmaceuticals, Inc. | 33,032 | $265K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 84,556 | $260K |
| MANEVeradermics Incorporated | 3,900 | $246K |
| ARDXARDELYX, INC. | 39,299 | $235K |
| SLDBSolid Biosciences Inc. | 30,493 | $220K |
| VCELVericel Corp | 6,718 | $216K |
| AQSTAquestive Therapeutics, Inc. | 51,817 | $215K |
| DFTXDefinium Therapeutics Inc. | 10,412 | $197K |
| OCGNOcugen, Inc. | 108,665 | $197K |
| LRMRLarimar Therapeutics, Inc. | 38,090 | $171K |
| RLMDRELMADA THERAPEUTICS, INC. | 23,247 | $162K |
| SIGASIGA TECHNOLOGIES INC | 25,644 | $137K |
| PRTAPROTHENA CORP PUBLIC LTD CO | 12,399 | $121K |
| RGNXREGENXBIO Inc. | 14,151 | $119K |
| LXRXLEXICON PHARMACEUTICALS, INC. | 75,110 | $117K |
| EDSAEdesa Biotech, Inc. | 19,650 | $103K |
| ZURAZura Bio Ltd | 16,146 | $96K |
| ELABPMGC Holdings Inc. | 14,800 | $89K |
| NBPNovaBridge Biosciences | 35,414 | $87K |
| XFORX4 Pharmaceuticals, Inc | 19,514 | $81K |
| LCTXLineage Cell Therapeutics, Inc. | 48,017 | $76K |
| IVVDInvivyd, Inc. | 52,531 | $68K |
| SVRASavara Inc | 11,549 | $63K |
| CCCCC4 Therapeutics, Inc. | 23,944 | $63K |
| PROKPROKIDNEY CORP. | 32,845 | $59K |
| MNOVMEDICINOVA INC | 36,376 | $50K |
| ZNTLZentalis Pharmaceuticals, Inc. | 20,600 | $48K |
| SPROSpero Therapeutics, Inc. | 20,314 | $48K |
| BDTXBlack Diamond Therapeutics, Inc. | 18,774 | $40K |
| GERNGERON CORP | 24,102 | $36K |
| IMUXIMMUNIC, INC. | 28,300 | $31K |
| PMCBPharmaCyte Biotech, Inc. | 27,009 | $18K |
| VTGNVistagen Therapeutics, Inc. | 26,589 | $15K |
| CGTXCOGNITION THERAPEUTICS INC | 10,000 | $8K |