| GILDGILEAD SCIENCES, INC. | 18,492 | $2.6M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 37,173 | $2.1M |
| IBRXImmunityBio, Inc. | 156,604 | $1.2M |
| GYREGYRE THERAPEUTICS, INC. | 170,837 | $1.2M |
| VKTXViking Therapeutics, Inc. | 31,615 | $1.0M |
| MRNAModerna, Inc. | 16,795 | $853K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 242,617 | $745K |
| REGNREGENERON PHARMACEUTICALS, INC. | 318 | $246K |
| ABSIAbsci Corporation | 64,646 | $194K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 4,943 | $150K |
| ANNXAnnexon, Inc. | 23,225 | $129K |
| BEAMBeam Therapeutics Inc. | 4,549 | $108K |
| ABUSArbutus Biopharma Corp | 22,666 | $102K |
| IMMXImmix Biopharma, Inc. | 10,000 | $91K |
| OGNOrganon & Co. | 13,605 | $81K |
| AQSTAquestive Therapeutics, Inc. | 17,805 | $74K |
| ADMAADMA BIOLOGICS, INC. | 8,172 | $74K |
| ARDXARDELYX, INC. | 10,276 | $62K |
| MNOVMEDICINOVA INC | 44,876 | $61K |
| INCYIncyte Corp. | 620 | $58K |
| INSMINSMED Inc | 304 | $50K |
| ANABANAPTYSBIO, INC | 788 | $44K |
| OCGNOcugen, Inc. | 23,860 | $43K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 11,482 | $40K |
| PULMPulmatrix, Inc. | 30,085 | $39K |
| NTLAIntellia Therapeutics, Inc. | 2,490 | $32K |
| ABCLAbCellera Biologics Inc. | 8,528 | $30K |
| HROWHARROW, INC. | 817 | $29K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 302 | $26K |
| ALTAltimmune, Inc. | 8,313 | $26K |
| TGTXTG THERAPEUTICS, INC. | 746 | $25K |
| DNAGinkgo Bioworks Holdings Inc. | 3,890 | $24K |
| SIGASIGA TECHNOLOGIES INC | 3,999 | $21K |
| ARGXARGENX SE | 27 | $20K |
| TERNTerns Pharmaceuticals, Inc. | 372 | $20K |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 56 | $19K |
| EDSAEdesa Biotech, Inc. | 3,502 | $18K |
| GERNGERON CORP | 11,711 | $17K |
| ROIVRoivant Sciences Ltd. | 618 | $17K |
| FLGTFulgent Genetics Inc. | 1,012 | $16K |
| RLAYRelay Therapeutics, Inc. | 1,464 | $15K |
| EXELEXELIXIS, INC. | 336 | $14K |
| BBIOBridgeBio Pharma, Inc. | 164 | $12K |
| IONSIONIS PHARMACEUTICALS INC | 161 | $12K |
| MPLTMapLight Therapeutics, Inc. | 557 | $11K |
| LCTXLineage Cell Therapeutics, Inc. | 7,135 | $11K |
| XERSXeris Biopharma Holdings, Inc. | 1,907 | $11K |
| BMEABiomea Fusion, Inc. | 7,079 | $11K |
| RVMDREVOLUTION MEDICINES, INC. | 109 | $11K |
| APLSApellis Pharmaceuticals, Inc. | 257 | $10K |
| NKTRNEKTAR THERAPEUTICS | 141 | $10K |
| GMABGenmab A/S | 370 | $10K |
| INOINOVIO PHARMACEUTICALS, INC. | 5,403 | $9K |
| SLSSELLAS Life Sciences Group, Inc. | 2,186 | $9K |
| PRLDPrelude Therapeutics Inc | 2,641 | $9K |
| ARQTArcutis Biotherapeutics, Inc. | 342 | $8K |
| CYTKCYTOKINETICS INC | 116 | $8K |
| ZVRAZEVRA THERAPEUTICS, INC. | 812 | $8K |
| PTGXProtagonist Therapeutics, Inc | 70 | $7K |
| DNLIDenali Therapeutics Inc. | 368 | $7K |
| VRDNViridian Therapeutics, Inc.\DE | 358 | $7K |
| LXRXLEXICON PHARMACEUTICALS, INC. | 4,081 | $6K |
| VYGRVoyager Therapeutics, Inc. | 1,642 | $6K |
| SLDBSolid Biosciences Inc. | 877 | $6K |
| ATAIAtai Beckley N.V. | 1,738 | $6K |
| SANASana Biotechnology, Inc. | 2,128 | $6K |
| SGMOQSANGAMO THERAPEUTICS, INC | 24,626 | $6K |
| CTXRCitius Pharmaceuticals, Inc. | 6,519 | $6K |
| SMMTSummit Therapeutics Inc. | 292 | $6K |
| SPRYARS Pharmaceuticals, Inc. | 650 | $5K |
| CNTNCanton Strategic Holdings, Inc. | 1,549 | $5K |
| SLNOSOLENO THERAPEUTICS INC | 149 | $5K |
| AVXLANAVEX LIFE SCIENCES CORP. | 1,579 | $5K |
| RLYBRallybio Corp | 524 | $5K |
| LRMRLarimar Therapeutics, Inc. | 1,038 | $5K |
| ONCBeOne Medicines Ltd. | 15 | $4K |
| NUVBNuvation Bio Inc. | 1,028 | $4K |
| AXSMAxsome Therapeutics, Inc. | 25 | $4K |
| IMUXIMMUNIC, INC. | 3,765 | $4K |
| MLTXMoonLake Immunotherapeutics | 213 | $4K |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 57 | $4K |
| IMVTImmunovant, Inc. | 141 | $4K |
| ANVSAnnovis Bio, Inc. | 1,522 | $3K |
| ARVNARVINAS, INC. | 315 | $3K |
| IMCRImmunocore Holdings plc | 103 | $3K |
| BMRNBIOMARIN PHARMACEUTICAL INC | 54 | $3K |
| IMNNImunon, Inc. | 1,027 | $3K |
| LTRNLantern Pharma Inc. | 2,144 | $3K |
| ACADACADIA PHARMACEUTICALS INC | 122 | $3K |
| KURAKura Oncology, Inc. | 334 | $3K |
| RZLTRezolute, Inc. | 832 | $3K |
| NGNENeurogene Inc. | 125 | $3K |
| CMPSCOMPASS Pathways plc | 440 | $2K |
| CELUCelularity Inc. | 1,823 | $2K |
| IRDOpus Genetics, Inc. | 530 | $2K |
| TVTXTravere Therapeutics, Inc. | 81 | $2K |
| HUMAHumacyte Inc. | 3,673 | $2K |
| QUREuniQure N.V. | 135 | $2K |
| FLNAFilana Therapeutics Inc. | 1,231 | $2K |
| RGNXREGENXBIO Inc. | 244 | $2K |
| SBFMSUNSHINE BIOPHARMA INC. | 1,834 | $2K |
| DFTXDefinium Therapeutics Inc. | 98 | $2K |
| BCABBioAtla, Inc. | 11,124 | $2K |
| DNTHDianthus Therapeutics, Inc. /DE/ | 21 | $2K |
| MESOMesoblast Limited | 100 | $2K |
| PHIOPhio Pharmaceuticals Corp. | 1,224 | $1K |
| FATEFATE THERAPEUTICS INC | 1,172 | $1K |
| IVVDInvivyd, Inc. | 1,046 | $1K |
| DAWNDay One Biopharmaceuticals, Inc. | 60 | $1K |
| ADPTAdaptive Biotechnologies Corp | 91 | $1K |
| MANEVeradermics Incorporated | 20 | $1K |
| CBIOCRESCENT BIOPHARMA, INC. | 68 | $1K |
| KALVKalVista Pharmaceuticals, Inc. | 62 | $1K |
| TNXPTonix Pharmaceuticals Holding Corp. | 89 | $1K |
| CNTACentessa Pharmaceuticals plc | 30 | $1K |
| ESPREsperion Therapeutics, Inc. | 433 | $1K |
| DAREDare Bioscience, Inc. | 645 | $1K |
| CHRSCoherus Oncology, Inc. | 689 | $1K |
| LQDALiquidia Corp | 30 | $1K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 33 | $1K |
| KYNBKYNTRA BIO INC. | 152 | $1K |
| BHVNBiohaven Ltd. | 120 | $1K |
| ELVNEnliven Therapeutics, Inc. | 25 | $980 |
| LENZLENZ Therapeutics, Inc. | 107 | $979 |
| CMPXCompass Therapeutics, Inc. | 184 | $973 |
| VERUVERU INC. | 435 | $961 |
| RCKTRocket Pharmaceuticals Inc. | 266 | $952 |
| OLMAOlema Pharmaceuticals, Inc. | 61 | $910 |
| ELTXElicio Therapeutics, Inc. | 82 | $877 |
| PRQRProQR Therapeutics N.V. | 515 | $834 |
| VCELVericel Corp | 25 | $804 |
| KTTAPasithea Therapeutics Corp. | 1,051 | $780 |
| ANTXAN2 Therapeutics, Inc. | 201 | $687 |
| ZURAZura Bio Ltd | 106 | $631 |
| ATOSATOSSA THERAPEUTICS, INC. | 113 | $594 |
| PGENPRECIGEN, INC. | 150 | $581 |
| ANIXAnixa Biosciences Inc | 223 | $575 |
| CLDXCelldex Therapeutics, Inc. | 18 | $571 |
| NBPNovaBridge Biosciences | 225 | $554 |
| CRVOCervoMed Inc. | 138 | $544 |
| ATNMActinium Pharmaceuticals, Inc. | 542 | $539 |
| PROKPROKIDNEY CORP. | 300 | $537 |
| LPCNLipocine Inc. | 67 | $535 |
| GOVXGeoVax Labs, Inc. | 384 | $530 |
| CRBPCorbus Pharmaceuticals Holdings, Inc. | 52 | $488 |
| KNSAKiniksa Pharmaceuticals International, plc | 10 | $482 |
| ALDXAldeyra Therapeutics, Inc. | 263 | $444 |
| XOMAXOMA Royalty Corporation | 14 | $439 |
| SGMTSagimet Biosciences Inc. | 84 | $439 |
| APGEApogee Therapeutics, Inc. | 5 | $421 |
| REVBREVELATION BIOSCIENCES, INC. | 344 | $413 |
| NRIXNurix Therapeutics, Inc. | 26 | $403 |
| ZBIOZenas BioPharma, Inc. | 20 | $391 |
| PLRXPLIANT THERAPEUTICS, INC. | 300 | $378 |
| MBIOMUSTANG BIO, INC. | 509 | $371 |
| DMRADamora Therapeutics, Inc. | 14 | $363 |
| QNTMQuantum Biopharma Ltd. | 75 | $362 |
| PBYIPUMA BIOTECHNOLOGY, INC. | 56 | $358 |
| ABEOABEONA THERAPEUTICS INC. | 74 | $332 |
| PLURPluri Inc. | 97 | $329 |
| FDMT4D Molecular Therapeutics, Inc. | 35 | $326 |
| GRCEGrace Therapeutics, Inc. | 70 | $324 |
| BIVIBIOVIE INC. | 231 | $323 |
| VIVSVivoSim Labs, INC. | 221 | $316 |
| FBRXForte Biosciences, Inc. | 12 | $311 |
| RNACCartesian Therapeutics, Inc. | 49 | $301 |
| OCULOCULAR THERAPEUTIX, INC | 35 | $296 |
| RLMDRELMADA THERAPEUTICS, INC. | 41 | $285 |
| GHRSGH Research PLC | 20 | $281 |
| ZYMEZymeworks Inc. | 11 | $275 |
| ADAGAdagene Inc. | 69 | $270 |
| CCCCC4 Therapeutics, Inc. | 101 | $266 |
| MRKRMarker Therapeutics, Inc. | 203 | $264 |
| ENSCEnsysce Biosciences Inc. | 486 | $262 |
| JBIOJade Biosciences, Inc. | 18 | $253 |
| BBLGBone Biologics Corp | 230 | $253 |
| SYRESpyre Therapeutics, Inc. | 5 | $252 |
| IMTXImmatics N.V. | 25 | $246 |
| MTVAMetaVia Inc. | 205 | $246 |
| EVOEvotec SE | 97 | $243 |
| OVIDOvid Therapeutics Inc. | 107 | $238 |
| CRDFCardiff Oncology, Inc. | 144 | $233 |
| EVAXEvaxion A/S | 62 | $231 |
| PTNPALATIN TECHNOLOGIES INC | 13 | $226 |
| XFORX4 Pharmaceuticals, Inc | 54 | $223 |
| BDTXBlack Diamond Therapeutics, Inc. | 103 | $219 |
| PLSEPulse Biosciences Inc Common Stock (DE) | 10 | $216 |
| CNTXContext Therapeutics Inc. | 78 | $204 |
| ORMPORAMED PHARMACEUTICALS INC. | 59 | $201 |
| LGNDLigand Pharmaceuticals Incorporated | 1 | $200 |
| NRSNNeuroSense Therapeutics Ltd. | 265 | $200 |
| SRRKScholar Rock Holding Corp | 4 | $197 |
| ALGSAligos Therapeutics, Inc. | 26 | $193 |
| ASRTAssertio Holdings, Inc. | 10 | $191 |
| XCUREXICURE, INC. | 43 | $183 |
| RVPHREVIVA PHARMACEUTICALS HOLDINGS, INC. | 250 | $182 |
| MAZEMaze Therapeutics, Inc. | 6 | $179 |
| VTGNVistagen Therapeutics, Inc. | 288 | $165 |
| STOKStoke Therapeutics, Inc. | 5 | $163 |
| ENVBEnveric Biosciences, Inc. | 83 | $161 |
| ORGOOrganogenesis Holdings Inc. | 65 | $154 |
| KODKodiak Sciences Inc. | 4 | $152 |
| SLNSilence Therapeutics Plc | 28 | $148 |
| PRTAPROTHENA CORP PUBLIC LTD CO | 15 | $146 |
| NNVCNANOVIRICIDES, INC. | 150 | $137 |
| CTMXCytomX Therapeutics, Inc. | 28 | $132 |
| ACETAdicet Bio, Inc. | 19 | $129 |
| HURATuHURA Biosciences, Inc./NV | 71 | $127 |
| PPBTPURPLE BIOTECH LTD. | 31 | $125 |
| LONALeonaBio, Inc. | 12 | $123 |
| CLNNClene Inc. | 25 | $123 |
| CODXCo-Diagnostics Inc. | 58 | $108 |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 2 | $103 |
| AEONAEON Biopharma, Inc. | 105 | $103 |
| RNAZTranscode Therapeutics, Inc. | 12 | $103 |
| CADLCandel Therapeutics, Inc. | 20 | $98 |
| BDRXBiodexa Pharmaceuticals Plc | 151 | $93 |
| TPSTTempest Therapeutics, Inc. | 56 | $92 |
| ALMSALUMIS INC. | 4 | $88 |
| TLPHTALPHERA, INC. | 113 | $84 |
| ADILADIAL PHARMACEUTICALS, INC. | 47 | $84 |
| WHWKWhitehawk Therapeutics, Inc. | 23 | $79 |
| AUTLAutolus Therapeutics plc | 55 | $76 |
| PHGEBiomX Inc. | 20 | $75 |
| PDSBPDS Biotechnology Corp | 118 | $71 |
| ALVOAlvotech | 20 | $69 |
| PTCTPTC THERAPEUTICS, INC. | 1 | $68 |
| HOWLWerewolf Therapeutics, Inc. | 80 | $67 |
| IRONDisc Medicine, Inc. | 1 | $64 |
| ZNTLZentalis Pharmaceuticals, Inc. | 27 | $63 |
| LGVNLongeveron Inc. | 60 | $62 |
| ELUTELUTIA INC. | 55 | $58 |
| PCVXVaxcyte, Inc. | 1 | $58 |
| JSPRJasper Therapeutics Inc. | 65 | $57 |
| SCLXSCILEX HOLDING CO | 8 | $53 |
| CALCCalciMedica, Inc. | 87 | $47 |
| OTLKOutlook Therapeutics, Inc. | 222 | $46 |
| CAMPCamp4 Therapeutics Corp | 10 | $44 |
| CMMBChemomab Therapeutics Ltd. | 28 | $44 |
| ALECAlector, Inc. | 20 | $43 |
| AGENAGENUS INC | 12 | $40 |
| BOLTBolt Biotherapeutics, Inc. | 10 | $40 |
| COGTCogent Biosciences, Inc. | 1 | $38 |
| LSTALISATA THERAPEUTICS, INC. | 7 | $35 |
| COCPCocrystal Pharma, Inc. | 33 | $33 |
| ARMPArmata Pharmaceuticals, Inc. | 3 | $31 |
| INDPIndaptus Therapeutics, Inc. | 17 | $31 |
| AYTUAYTU BIOPHARMA, INC | 11 | $30 |
| KLRSKalaris Therapeutics, Inc. | 5 | $29 |
| BCYCBICYCLE THERAPEUTICS PLC | 6 | $28 |
| PHVSPharvaris N.V. | 1 | $28 |
| ALXOALX ONCOLOGY HOLDINGS INC | 14 | $28 |
| CLRBCellectar Biosciences, Inc. | 11 | $28 |
| AKTXAkari Therapeutics Plc | 5 | $26 |
| TOVXTheriva Biologics, Inc. | 131 | $26 |
| SLXNSilexion Therapeutics Corp | 20 | $26 |
| ORICOric Pharmaceuticals, Inc. | 2 | $25 |
| CSBRCHAMPIONS ONCOLOGY, INC. | 4 | $23 |
| ALZNAlzamend Neuro, Inc. | 22 | $23 |
| KROSKeros Therapeutics, Inc. | 2 | $22 |
| ACXPAcurx Pharmaceuticals, Inc. | 6 | $22 |
| TNGXTango Therapeutics, Inc. | 1 | $21 |
| SPROSpero Therapeutics, Inc. | 9 | $21 |
| AGMBAgomAb Therapeutics NV | 2 | $21 |
| BTAIBioXcel Therapeutics, Inc. | 14 | $19 |
| SVRASavara Inc | 3 | $16 |
| TVRDTvardi Therapeutics, Inc. | 5 | $16 |
| SCNXScienture Holdings, Inc. | 55 | $16 |
| CGEMCullinan Therapeutics, Inc. | 1 | $14 |
| QNCXQuince Therapeutics, Inc. | 135 | $14 |
| MISTMilestone Pharmaceuticals Inc. | 11 | $13 |
| QNRXQuoin Pharmaceuticals, Ltd. | 2 | $13 |
| CGTXCOGNITION THERAPEUTICS INC | 16 | $12 |
| KRROKorro Bio, Inc. | 1 | $11 |
| BCDABioCardia, Inc. | 9 | $11 |
| GRIGRI Bio, Inc. | 4 | $9 |
| GLMDGalmed Pharmaceuticals Ltd. | 16 | $8 |
| ADXNAddex Therapeutics Ltd. | 1 | $6 |
| PYPDPolyPid Ltd. | 1 | $4 |
| SPRCSciSparc Ltd. | 1 | $4 |
| CATXPerspective Therapeutics, Inc. | 1 | $4 |
| IXHLIncannex Healthcare Inc. | 1 | $3 |
| RDHLRedHill Biopharma Ltd. | 4 | $3 |
| OPKOPKO HEALTH, INC. | 2 | $2 |
| PLXProtalix BioTherapeutics, Inc. | 1 | $2 |
| PMCBPharmaCyte Biotech, Inc. | 3 | $2 |
| CELZCREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. | 1 | $2 |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 1 | $1 |
| LITSLite Strategy, Inc. | 1 | $1 |
| ASBPAspire Biopharma Holdings Inc. | 1 | $1 |
| IMMPImmutep Limited | 2 | $1 |