| GILDGILEAD SCIENCES, INC. | 1,811,223 | $252.4M |
| REGNREGENERON PHARMACEUTICALS, INC. | 152,397 | $117.7M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 174,013 | $57.6M |
| INSMINSMED Inc | 283,141 | $46.3M |
| INCYIncyte Corp. | 49,678 | $4.7M |
| MRNAModerna, Inc. | 71,342 | $3.6M |
| BBIOBridgeBio Pharma, Inc. | 31,677 | $2.4M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 31,498 | $2.0M |
| CYTKCYTOKINETICS INC | 27,777 | $1.8M |
| PCVXVaxcyte, Inc. | 24,449 | $1.4M |
| AXSMAxsome Therapeutics, Inc. | 8,296 | $1.4M |
| ROIVRoivant Sciences Ltd. | 50,102 | $1.4M |
| TERNTerns Pharmaceuticals, Inc. | 25,571 | $1.3M |
| PTGXProtagonist Therapeutics, Inc | 11,918 | $1.3M |
| PTCTPTC THERAPEUTICS, INC. | 15,970 | $1.1M |
| NUVLNuvalent, Inc. | 10,528 | $1.1M |
| COGTCogent Biosciences, Inc. | 28,006 | $1.1M |
| FOLDAMICUS THERAPEUTICS, INC. | 68,562 | $991K |
| JAZZJazz Pharmaceuticals plc | 5,191 | $981K |
| EXELEXELIXIS, INC. | 22,034 | $945K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 10,720 | $932K |
| ARGXARGENX SE | 1,269 | $927K |
| BMRNBIOMARIN PHARMACEUTICAL INC | 16,309 | $921K |
| RVMDREVOLUTION MEDICINES, INC. | 8,865 | $862K |
| SRRKScholar Rock Holding Corp | 17,218 | $846K |
| LGNDLigand Pharmaceuticals Incorporated | 3,910 | $781K |
| APGEApogee Therapeutics, Inc. | 8,886 | $748K |
| TGTXTG THERAPEUTICS, INC. | 22,500 | $747K |
| DAWNDay One Biopharmaceuticals, Inc. | 33,247 | $713K |
| IBRXImmunityBio, Inc. | 88,769 | $681K |
| SYRESpyre Therapeutics, Inc. | 13,498 | $681K |
| SMMTSummit Therapeutics Inc. | 34,686 | $658K |
| ACADACADIA PHARMACEUTICALS INC | 27,197 | $605K |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 11,182 | $578K |
| IONSIONIS PHARMACEUTICALS INC | 7,390 | $555K |
| DNLIDenali Therapeutics Inc. | 27,737 | $533K |
| SNYSanofi | 10,949 | $528K |
| IMVTImmunovant, Inc. | 20,921 | $520K |
| ARQTArcutis Biotherapeutics, Inc. | 21,499 | $507K |
| TVTXTravere Therapeutics, Inc. | 16,086 | $478K |
| TNGXTango Therapeutics, Inc. | 22,124 | $463K |
| BEAMBeam Therapeutics Inc. | 18,417 | $439K |
| DNTHDianthus Therapeutics, Inc. /DE/ | 5,197 | $436K |
| ONCBeOne Medicines Ltd. | 1,430 | $425K |
| ADMAADMA BIOLOGICS, INC. | 46,794 | $422K |
| ADPTAdaptive Biotechnologies Corp | 28,551 | $396K |
| ORKAOruka Therapeutics, Inc. | 7,756 | $380K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 10,805 | $366K |
| IRONDisc Medicine, Inc. | 5,688 | $364K |
| LQDALiquidia Corp | 9,492 | $358K |
| DFTXDefinium Therapeutics Inc. | 18,731 | $354K |
| INVAInnoviva, Inc. | 14,942 | $348K |
| ALMSALUMIS INC. | 15,591 | $343K |
| ELVNEnliven Therapeutics, Inc. | 8,359 | $328K |
| VCELVericel Corp | 10,113 | $325K |
| STOKStoke Therapeutics, Inc. | 9,654 | $314K |
| OCULOCULAR THERAPEUTIX, INC | 36,992 | $313K |
| KODKodiak Sciences Inc. | 8,216 | $313K |
| ABVXAbivax SA | 2,748 | $306K |
| ANIPANI PHARMACEUTICALS INC | 3,936 | $303K |
| CLDXCelldex Therapeutics, Inc. | 9,493 | $301K |
| NRIXNurix Therapeutics, Inc. | 19,341 | $300K |
| RCUSArcus Biosciences, Inc. | 13,053 | $282K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 89,793 | $276K |
| NTLAIntellia Therapeutics, Inc. | 21,380 | $274K |
| APLSApellis Pharmaceuticals, Inc. | 6,809 | $274K |
| ARDXARDELYX, INC. | 45,707 | $274K |
| ZYMEZymeworks Inc. | 10,574 | $265K |
| SLNOSOLENO THERAPEUTICS INC | 7,303 | $245K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 67,326 | $236K |
| VRDNViridian Therapeutics, Inc.\DE | 11,794 | $231K |
| HROWHARROW, INC. | 6,231 | $220K |
| ANABANAPTYSBIO, INC | 3,884 | $215K |
| CNTACentessa Pharmaceuticals plc | 5,351 | $213K |
| OLMAOlema Pharmaceuticals, Inc. | 13,710 | $204K |
| ORICOric Pharmaceuticals, Inc. | 14,079 | $178K |
| XERSXeris Biopharma Holdings, Inc. | 30,480 | $177K |
| SVRASavara Inc | 30,342 | $166K |
| PGENPRECIGEN, INC. | 41,961 | $162K |
| GERNGERON CORP | 107,731 | $161K |
| OPKOPKO HEALTH, INC. | 140,658 | $160K |
| NUVBNuvation Bio Inc. | 34,949 | $150K |
| CGEMCullinan Therapeutics, Inc. | 10,465 | $149K |
| BHVNBiohaven Ltd. | 17,045 | $144K |
| ANNXAnnexon, Inc. | 25,595 | $142K |
| ABUSArbutus Biopharma Corp | 30,551 | $137K |
| KURAKura Oncology, Inc. | 15,582 | $127K |
| ESPREsperion Therapeutics, Inc. | 45,615 | $125K |
| ARVNARVINAS, INC. | 10,920 | $116K |
| SLSSELLAS Life Sciences Group, Inc. | 24,915 | $105K |
| SANASana Biotechnology, Inc. | 36,256 | $104K |
| SPRYARS Pharmaceuticals, Inc. | 12,974 | $104K |
| CMPXCompass Therapeutics, Inc. | 18,703 | $99K |
| ZVRAZEVRA THERAPEUTICS, INC. | 10,594 | $99K |
| SLDBSolid Biosciences Inc. | 12,033 | $87K |
| AQSTAquestive Therapeutics, Inc. | 20,239 | $84K |
| ALTAltimmune, Inc. | 24,523 | $76K |
| RCKTRocket Pharmaceuticals Inc. | 17,143 | $61K |
| ATAIAtai Beckley N.V. | 16,248 | $58K |
| LRMRLarimar Therapeutics, Inc. | 11,700 | $53K |
| AVXLANAVEX LIFE SCIENCES CORP. | 16,829 | $52K |
| ALVOAlvotech | 14,776 | $51K |
| ABCLAbCellera Biologics Inc. | 13,562 | $47K |
| CHRSCoherus Oncology, Inc. | 21,700 | $37K |
| RZLTRezolute, Inc. | 10,494 | $32K |
| ALECAlector, Inc. | 13,188 | $28K |
| PLXProtalix BioTherapeutics, Inc. | 10,589 | $23K |
| HUMAHumacyte Inc. | 32,125 | $19K |
| FATEFATE THERAPEUTICS INC | 15,764 | $19K |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 22,275 | $18K |
| IVVDInvivyd, Inc. | 12,396 | $16K |