| GILDGILEAD SCIENCES, INC. | 1,769,886 | $246.7M |
| INSMINSMED Inc | 916,464 | $149.9M |
| BBIOBridgeBio Pharma, Inc. | 1,330,415 | $98.8M |
| REGNREGENERON PHARMACEUTICALS, INC. | 120,425 | $93.0M |
| GPCRStructure Therapeutics Inc. | 1,753,764 | $84.5M |
| CYTKCYTOKINETICS INC | 1,093,485 | $72.1M |
| AXSMAxsome Therapeutics, Inc. | 350,488 | $59.2M |
| PTGXProtagonist Therapeutics, Inc | 367,822 | $38.8M |
| PTCTPTC THERAPEUTICS, INC. | 515,001 | $35.1M |
| ABVXAbivax SA | 312,274 | $34.8M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 490,122 | $30.7M |
| DNLIDenali Therapeutics Inc. | 1,478,486 | $28.4M |
| ROIVRoivant Sciences Ltd. | 1,005,533 | $27.9M |
| JAZZJazz Pharmaceuticals plc | 135,504 | $25.6M |
| EXELEXELIXIS, INC. | 583,744 | $25.0M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 428,607 | $24.2M |
| ADPTAdaptive Biotechnologies Corp | 1,704,887 | $23.7M |
| ALMSALUMIS INC. | 1,058,051 | $23.3M |
| TGTXTG THERAPEUTICS, INC. | 665,526 | $22.1M |
| INCYIncyte Corp. | 225,492 | $21.2M |
| APLSApellis Pharmaceuticals, Inc. | 499,053 | $20.1M |
| MRNAModerna, Inc. | 387,718 | $19.7M |
| LGNDLigand Pharmaceuticals Incorporated | 95,716 | $19.1M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 341,117 | $17.6M |
| ACADACADIA PHARMACEUTICALS INC | 768,224 | $17.1M |
| VKTXViking Therapeutics, Inc. | 525,484 | $17.1M |
| IMCRImmunocore Holdings plc | 519,130 | $15.7M |
| ADMAADMA BIOLOGICS, INC. | 1,390,313 | $12.5M |
| ANIPANI PHARMACEUTICALS INC | 129,148 | $9.9M |
| INVAInnoviva, Inc. | 418,731 | $9.8M |
| RCUSArcus Biosciences, Inc. | 413,778 | $8.9M |
| VCELVericel Corp | 247,324 | $8.0M |
| FOLDAMICUS THERAPEUTICS, INC. | 529,407 | $7.7M |
| OGNOrganon & Co. | 1,260,689 | $7.6M |
| BCYCBICYCLE THERAPEUTICS PLC | 1,174,625 | $5.5M |
| ARQTArcutis Biotherapeutics, Inc. | 168,826 | $4.0M |
| COGTCogent Biosciences, Inc. | 83,944 | $3.2M |
| TEVATeva Pharmaceutical Industries Limited | 97,269 | $2.9M |
| STOKStoke Therapeutics, Inc. | 63,933 | $2.1M |
| ZYMEZymeworks Inc. | 78,547 | $2.0M |
| ARGXARGENX SE | 2,675 | $2.0M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 5,649 | $1.9M |
| HROWHARROW, INC. | 51,869 | $1.8M |
| VRDNViridian Therapeutics, Inc.\DE | 75,200 | $1.5M |
| XERSXeris Biopharma Holdings, Inc. | 208,507 | $1.2M |
| ESPREsperion Therapeutics, Inc. | 422,776 | $1.2M |
| KROSKeros Therapeutics, Inc. | 59,594 | $658K |
| IONSIONIS PHARMACEUTICALS INC | 7,019 | $527K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 5,637 | $490K |
| RVMDREVOLUTION MEDICINES, INC. | 4,567 | $444K |
| NUVLNuvalent, Inc. | 3,610 | $370K |
| PCVXVaxcyte, Inc. | 5,275 | $307K |
| SRRKScholar Rock Holding Corp | 6,113 | $301K |
| APGEApogee Therapeutics, Inc. | 3,221 | $271K |
| SYRESpyre Therapeutics, Inc. | 4,299 | $217K |
| TERNTerns Pharmaceuticals, Inc. | 4,064 | $214K |
| IBRXImmunityBio, Inc. | 19,710 | $151K |
| DRTSAlpha Tau Medical Ltd. | 18,677 | $132K |
| OCULOCULAR THERAPEUTIX, INC | 13,623 | $115K |
| ARDXARDELYX, INC. | 17,570 | $105K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 33,161 | $102K |
| GERNGERON CORP | 39,519 | $59K |
| SVRASavara Inc | 10,358 | $57K |
| SLSSELLAS Life Sciences Group, Inc. | 12,429 | $53K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 14,329 | $50K |
| PGENPRECIGEN, INC. | 12,844 | $50K |
| ABUSArbutus Biopharma Corp | 10,977 | $49K |
| NUVBNuvation Bio Inc. | 11,230 | $48K |
| ABSIAbsci Corporation | 10,296 | $31K |
| OPKOPKO HEALTH, INC. | 17,740 | $20K |