| GILDGILEAD SCIENCES, INC. | 2,574,822 | $356.9M |
| REGNREGENERON PHARMACEUTICALS, INC. | 337,254 | $258.4M |
| INSMINSMED Inc | 1,102,248 | $178.7M |
| ARGXARGENX SE | 148,306 | $108.0M |
| IONSIONIS PHARMACEUTICALS INC | 1,434,995 | $107.1M |
| BBIOBridgeBio Pharma, Inc. | 1,381,184 | $101.5M |
| TERNTerns Pharmaceuticals, Inc. | 1,655,575 | $87.3M |
| INCYIncyte Corp. | 916,188 | $84.8M |
| PTCTPTC THERAPEUTICS, INC. | 1,183,720 | $80.1M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 1,273,266 | $79.6M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 237,920 | $77.5M |
| ROIVRoivant Sciences Ltd. | 2,673,233 | $74.0M |
| AXSMAxsome Therapeutics, Inc. | 415,983 | $70.3M |
| COGTCogent Biosciences, Inc. | 1,798,768 | $68.8M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 1,193,661 | $67.1M |
| PTGXProtagonist Therapeutics, Inc | 581,083 | $61.2M |
| TGTXTG THERAPEUTICS, INC. | 1,747,373 | $58.0M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 667,046 | $57.3M |
| RVMDREVOLUTION MEDICINES, INC. | 557,560 | $53.6M |
| CYTKCYTOKINETICS INC | 750,953 | $49.3M |
| DNLIDenali Therapeutics Inc. | 2,558,865 | $48.4M |
| ACADACADIA PHARMACEUTICALS INC | 2,026,044 | $44.7M |
| SRRKScholar Rock Holding Corp | 875,084 | $43.0M |
| NRIXNurix Therapeutics, Inc. | 2,726,138 | $42.3M |
| NUVLNuvalent, Inc. | 410,485 | $42.1M |
| PCVXVaxcyte, Inc. | 700,311 | $40.7M |
| ELVNEnliven Therapeutics, Inc. | 929,544 | $36.4M |
| MRNAModerna, Inc. | 676,117 | $32.8M |
| JAZZJazz Pharmaceuticals plc | 173,250 | $31.8M |
| SNYSanofi | 678,092 | $31.7M |
| KNSAKiniksa Pharmaceuticals International, plc | 623,288 | $30.0M |
| CLDXCelldex Therapeutics, Inc. | 923,696 | $29.3M |
| GMABGenmab A/S | 1,077,471 | $28.9M |
| EXELEXELIXIS, INC. | 628,601 | $26.4M |
| SYRESpyre Therapeutics, Inc. | 491,649 | $24.8M |
| IRONDisc Medicine, Inc. | 387,005 | $24.7M |
| SMMTSummit Therapeutics Inc. | 1,323,179 | $24.0M |
| VKTXViking Therapeutics, Inc. | 696,301 | $22.7M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 450,764 | $22.3M |
| APGEApogee Therapeutics, Inc. | 261,050 | $22.0M |
| SLNOSOLENO THERAPEUTICS INC | 616,217 | $20.6M |
| TEVATeva Pharmaceutical Industries Limited | 580,428 | $17.5M |
| TVTXTravere Therapeutics, Inc. | 529,757 | $14.7M |
| FOLDAMICUS THERAPEUTICS, INC. | 893,901 | $12.9M |
| SVRASavara Inc | 2,275,381 | $12.4M |
| IMVTImmunovant, Inc. | 472,381 | $11.7M |
| LGNDLigand Pharmaceuticals Incorporated | 60,737 | $11.7M |
| ABVXAbivax SA | 103,545 | $11.2M |
| APLSApellis Pharmaceuticals, Inc. | 426,821 | $7.6M |
| UPBUpstream Bio, Inc. | 733,431 | $6.6M |
| BEAMBeam Therapeutics Inc. | 297,504 | $6.5M |
| VRDNViridian Therapeutics, Inc.\DE | 314,031 | $6.1M |
| IBRXImmunityBio, Inc. | 830,137 | $5.6M |
| AGIOAGIOS PHARMACEUTICALS, INC. | 128,814 | $3.8M |
| OLMAOlema Pharmaceuticals, Inc. | 217,023 | $3.2M |
| ARQTArcutis Biotherapeutics, Inc. | 138,112 | $3.0M |
| OCULOCULAR THERAPEUTIX, INC | 362,596 | $2.7M |
| CNTACentessa Pharmaceuticals plc | 96,910 | $2.7M |
| ONCBeOne Medicines Ltd. | 1,500 | $445K |
| DNTHDianthus Therapeutics, Inc. /DE/ | 4,924 | $413K |
| LQDALiquidia Corp | 10,460 | $395K |
| ADMAADMA BIOLOGICS, INC. | 41,036 | $370K |
| DAWNDay One Biopharmaceuticals, Inc. | 13,034 | $279K |
| OGNOrganon & Co. | 45,763 | $274K |
| VCELVericel Corp | 8,408 | $270K |
| NKTRNEKTAR THERAPEUTICS | 3,718 | $268K |
| ANIPANI PHARMACEUTICALS INC | 3,436 | $264K |
| INVAInnoviva, Inc. | 11,162 | $260K |
| DFTXDefinium Therapeutics Inc. | 13,295 | $251K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 8,224 | $250K |
| RCUSArcus Biosciences, Inc. | 11,462 | $248K |
| STOKStoke Therapeutics, Inc. | 7,581 | $247K |
| ARDXARDELYX, INC. | 40,610 | $243K |
| ZYMEZymeworks Inc. | 9,256 | $232K |
| ALMSALUMIS INC. | 10,491 | $231K |
| ADPTAdaptive Biotechnologies Corp | 15,939 | $221K |
| NTLAIntellia Therapeutics, Inc. | 16,933 | $217K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 70,303 | $216K |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 6,533 | $209K |
| HROWHARROW, INC. | 5,711 | $201K |
| NUVBNuvation Bio Inc. | 40,984 | $176K |
| XERSXeris Biopharma Holdings, Inc. | 29,999 | $174K |
| BHVNBiohaven Ltd. | 18,909 | $160K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 43,048 | $151K |
| PGENPRECIGEN, INC. | 35,891 | $139K |
| ABUSArbutus Biopharma Corp | 23,927 | $108K |
| GERNGERON CORP | 71,528 | $107K |
| KURAKura Oncology, Inc. | 11,756 | $96K |
| SANASana Biotechnology, Inc. | 32,132 | $93K |
| ANNXAnnexon, Inc. | 16,701 | $93K |
| SPRYARS Pharmaceuticals, Inc. | 10,362 | $83K |
| ATAIAtai Beckley N.V. | 22,253 | $79K |
| CTMXCytomX Therapeutics, Inc. | 16,606 | $78K |
| CMPXCompass Therapeutics, Inc. | 14,432 | $76K |
| OPKOPKO HEALTH, INC. | 65,495 | $75K |