| ARGXARGENX SE | 133,347 | $97.4M |
| GILDGILEAD SCIENCES, INC. | 299,734 | $41.8M |
| INCYIncyte Corp. | 219,881 | $20.7M |
| ONCBeOne Medicines Ltd. | 62,917 | $18.7M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 325,851 | $18.4M |
| EXELEXELIXIS, INC. | 372,600 | $16.0M |
| RDYDR REDDYS LABORATORIES LTD | 1,059,831 | $14.7M |
| REGNREGENERON PHARMACEUTICALS, INC. | 17,004 | $13.1M |
| JAZZJazz Pharmaceuticals plc | 42,723 | $8.1M |
| ACADACADIA PHARMACEUTICALS INC | 246,297 | $5.5M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 16,280 | $5.4M |
| ARQTArcutis Biotherapeutics, Inc. | 154,566 | $3.6M |
| MPLTMapLight Therapeutics, Inc. | 142,016 | $2.9M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 32,888 | $2.9M |
| TLXTelix Pharmaceuticals Limited | 289,917 | $2.8M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 49,946 | $2.8M |
| PCVXVaxcyte, Inc. | 47,023 | $2.7M |
| IRONDisc Medicine, Inc. | 39,400 | $2.5M |
| AXSMAxsome Therapeutics, Inc. | 13,163 | $2.2M |
| IONSIONIS PHARMACEUTICALS INC | 25,410 | $1.9M |
| PTCTPTC THERAPEUTICS, INC. | 25,988 | $1.8M |
| ESPREsperion Therapeutics, Inc. | 580,705 | $1.6M |
| ABSIAbsci Corporation | 530,130 | $1.6M |
| RXRXRECURSION PHARMACEUTICALS, INC. | 400,762 | $1.2M |
| NTLAIntellia Therapeutics, Inc. | 93,620 | $1.2M |
| SLNOSOLENO THERAPEUTICS INC | 32,664 | $1.1M |
| ABCLAbCellera Biologics Inc. | 305,224 | $1.1M |
| KNSAKiniksa Pharmaceuticals International, plc | 21,432 | $1.0M |
| MRNAModerna, Inc. | 11,364 | $577K |
| BBIOBridgeBio Pharma, Inc. | 7,421 | $551K |
| SNYSanofi | 10,783 | $520K |
| TERNTerns Pharmaceuticals, Inc. | 7,173 | $378K |
| FOLDAMICUS THERAPEUTICS, INC. | 24,184 | $350K |
| ADPTAdaptive Biotechnologies Corp | 25,098 | $348K |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 4,567 | $286K |
| ADMAADMA BIOLOGICS, INC. | 29,757 | $268K |
| ZYMEZymeworks Inc. | 10,602 | $265K |
| ARDXARDELYX, INC. | 44,269 | $265K |
| DAWNDay One Biopharmaceuticals, Inc. | 9,364 | $201K |
| PLXProtalix BioTherapeutics, Inc. | 86,617 | $188K |
| SIGASIGA TECHNOLOGIES INC | 24,519 | $131K |
| KROSKeros Therapeutics, Inc. | 11,705 | $129K |
| PBYIPUMA BIOTECHNOLOGY, INC. | 17,970 | $115K |
| GERNGERON CORP | 64,879 | $97K |
| CYTKCYTOKINETICS INC | 1,369 | $90K |
| IVVDInvivyd, Inc. | 20,933 | $27K |
| CHRSCoherus Oncology, Inc. | 10,514 | $18K |