| AXSMAxsome Therapeutics, Inc. | 60,994 | $10.3M |
| JAZZJazz Pharmaceuticals plc | 39,148 | $7.4M |
| TGTXTG THERAPEUTICS, INC. | 206,538 | $6.9M |
| TEVATeva Pharmaceutical Industries Limited | 142,344 | $4.3M |
| VKTXViking Therapeutics, Inc. | 60,573 | $2.0M |
| EXELEXELIXIS, INC. | 43,450 | $1.9M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 21,892 | $1.2M |
| REGNREGENERON PHARMACEUTICALS, INC. | 1,468 | $1.1M |
| GILDGILEAD SCIENCES, INC. | 7,093 | $989K |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 8,704 | $546K |
| INCYIncyte Corp. | 5,333 | $502K |
| ARGXARGENX SE | 629 | $459K |
| MRNAModerna, Inc. | 8,149 | $414K |
| INSMINSMED Inc | 2,291 | $375K |
| ONCBeOne Medicines Ltd. | 1,000 | $297K |
| MAZEMaze Therapeutics, Inc. | 8,988 | $268K |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 482 | $159K |
| BMRNBIOMARIN PHARMACEUTICAL INC | 2,178 | $123K |
| SNYSanofi | 2,295 | $111K |
| PTCTPTC THERAPEUTICS, INC. | 1,322 | $90K |
| COGTCogent Biosciences, Inc. | 2,224 | $86K |
| IMCRImmunocore Holdings plc | 2,749 | $83K |
| TERNTerns Pharmaceuticals, Inc. | 1,424 | $75K |
| IONSIONIS PHARMACEUTICALS INC | 950 | $71K |
| TVTXTravere Therapeutics, Inc. | 2,298 | $68K |
| LGNDLigand Pharmaceuticals Incorporated | 341 | $68K |
| CTORCITIUS ONCOLOGY, INC. | 107,424 | $67K |
| BBIOBridgeBio Pharma, Inc. | 801 | $59K |
| PBYIPUMA BIOTECHNOLOGY, INC. | 6,908 | $44K |
| BHVNBiohaven Ltd. | 4,195 | $35K |
| CYTKCYTOKINETICS INC | 506 | $33K |
| QUREuniQure N.V. | 1,989 | $33K |
| KROSKeros Therapeutics, Inc. | 2,852 | $31K |
| SRRKScholar Rock Holding Corp | 626 | $31K |
| LQDALiquidia Corp | 812 | $31K |
| ACADACADIA PHARMACEUTICALS INC | 1,367 | $30K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 7,655 | $24K |
| RDYDR REDDYS LABORATORIES LTD | 1,413 | $20K |
| NTLAIntellia Therapeutics, Inc. | 1,498 | $19K |
| APLSApellis Pharmaceuticals, Inc. | 471 | $19K |
| PCVXVaxcyte, Inc. | 324 | $19K |
| TNXPTonix Pharmaceuticals Holding Corp. | 1,356 | $19K |
| NUVBNuvation Bio Inc. | 3,788 | $16K |
| SANASana Biotechnology, Inc. | 5,400 | $16K |
| ABCLAbCellera Biologics Inc. | 4,132 | $14K |
| DAWNDay One Biopharmaceuticals, Inc. | 640 | $14K |
| IBRXImmunityBio, Inc. | 1,715 | $13K |
| OGNOrganon & Co. | 2,172 | $13K |
| LYELLyell Immunopharma, Inc. | 648 | $13K |
| AQSTAquestive Therapeutics, Inc. | 3,001 | $12K |
| ELABPMGC Holdings Inc. | 2,000 | $12K |
| FOLDAMICUS THERAPEUTICS, INC. | 814 | $12K |
| ARDXARDELYX, INC. | 1,806 | $11K |
| RVMDREVOLUTION MEDICINES, INC. | 110 | $11K |
| CELUCelularity Inc. | 8,000 | $11K |
| BEAMBeam Therapeutics Inc. | 392 | $9K |
| KURAKura Oncology, Inc. | 1,075 | $9K |
| ARQTArcutis Biotherapeutics, Inc. | 294 | $7K |
| AVXLANAVEX LIFE SCIENCES CORP. | 2,090 | $6K |
| CTXRCitius Pharmaceuticals, Inc. | 7,083 | $6K |
| HUMAHumacyte Inc. | 9,120 | $6K |
| RCKTRocket Pharmaceuticals Inc. | 1,544 | $6K |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 106 | $5K |
| TNGXTango Therapeutics, Inc. | 233 | $5K |
| CGEMCullinan Therapeutics, Inc. | 313 | $4K |
| ARVNARVINAS, INC. | 413 | $4K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 46 | $4K |
| KNSAKiniksa Pharmaceuticals International, plc | 82 | $4K |
| SLSSELLAS Life Sciences Group, Inc. | 925 | $4K |
| SCLXSCILEX HOLDING CO | 576 | $4K |
| ORICOric Pharmaceuticals, Inc. | 297 | $4K |
| ANNXAnnexon, Inc. | 645 | $4K |
| NUVLNuvalent, Inc. | 34 | $3K |
| SGMOQSANGAMO THERAPEUTICS, INC | 13,509 | $3K |
| SMMTSummit Therapeutics Inc. | 169 | $3K |
| VCELVericel Corp | 86 | $3K |
| GMABGenmab A/S | 102 | $3K |
| ALDXAldeyra Therapeutics, Inc. | 1,442 | $2K |
| ZYMEZymeworks Inc. | 96 | $2K |
| APGEApogee Therapeutics, Inc. | 27 | $2K |
| SLDBSolid Biosciences Inc. | 298 | $2K |
| RGNXREGENXBIO Inc. | 244 | $2K |
| ADPTAdaptive Biotechnologies Corp | 126 | $2K |
| ROIVRoivant Sciences Ltd. | 62 | $2K |
| ANIXAnixa Biosciences Inc | 660 | $2K |
| ORMPORAMED PHARMACEUTICALS INC. | 500 | $2K |
| RZLTRezolute, Inc. | 541 | $2K |
| ADMAADMA BIOLOGICS, INC. | 174 | $2K |
| FLGTFulgent Genetics Inc. | 86 | $1K |
| ALMSALUMIS INC. | 55 | $1K |
| SYRESpyre Therapeutics, Inc. | 24 | $1K |
| FATEFATE THERAPEUTICS INC | 908 | $1K |
| CHRSCoherus Oncology, Inc. | 610 | $1K |
| INVAInnoviva, Inc. | 44 | $1K |
| AKTXAkari Therapeutics Plc | 181 | $932 |
| FDMT4D Molecular Therapeutics, Inc. | 78 | $726 |
| LRMRLarimar Therapeutics, Inc. | 155 | $698 |
| HURATuHURA Biosciences, Inc./NV | 308 | $551 |
| KRROKorro Bio, Inc. | 45 | $509 |
| OPKOPKO HEALTH, INC. | 403 | $459 |
| OCULOCULAR THERAPEUTIX, INC | 53 | $449 |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 116 | $407 |
| RCUSArcus Biosciences, Inc. | 18 | $389 |
| RNACCartesian Therapeutics, Inc. | 62 | $381 |
| SIGASIGA TECHNOLOGIES INC | 61 | $326 |
| CMPSCOMPASS Pathways plc | 50 | $276 |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 336 | $269 |
| DNAGinkgo Bioworks Holdings Inc. | 43 | $264 |
| ANVSAnnovis Bio, Inc. | 110 | $245 |
| KODKodiak Sciences Inc. | 6 | $229 |
| VRDNViridian Therapeutics, Inc.\DE | 10 | $196 |
| IRONDisc Medicine, Inc. | 3 | $192 |
| ABSIAbsci Corporation | 63 | $189 |
| DNLIDenali Therapeutics Inc. | 9 | $173 |
| STOKStoke Therapeutics, Inc. | 5 | $163 |
| CLDXCelldex Therapeutics, Inc. | 5 | $159 |
| BIOABioAge Labs, Inc. | 9 | $157 |
| LENZLENZ Therapeutics, Inc. | 17 | $156 |
| IMVTImmunovant, Inc. | 6 | $149 |
| ORKAOruka Therapeutics, Inc. | 3 | $147 |
| PRTAPROTHENA CORP PUBLIC LTD CO | 15 | $146 |
| RVPHREVIVA PHARMACEUTICALS HOLDINGS, INC. | 200 | $146 |
| VYGRVoyager Therapeutics, Inc. | 36 | $139 |
| TVRDTvardi Therapeutics, Inc. | 36 | $114 |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 3 | $96 |
| ASRTAssertio Holdings, Inc. | 5 | $95 |
| OLMAOlema Pharmaceuticals, Inc. | 6 | $89 |
| AARDAardvark Therapeutics, Inc. | 21 | $79 |
| ANIPANI PHARMACEUTICALS INC | 1 | $77 |
| AGIOAGIOS PHARMACEUTICALS, INC. | 2 | $68 |
| SILOSilo Pharma, Inc. | 175 | $63 |
| ANABANAPTYSBIO, INC | 1 | $55 |
| XERSXeris Biopharma Holdings, Inc. | 6 | $35 |
| CMPXCompass Therapeutics, Inc. | 6 | $32 |
| CUECue Biopharma, Inc. | 100 | $23 |
| NGNENeurogene Inc. | 1 | $20 |
| BTAIBioXcel Therapeutics, Inc. | 13 | $17 |
| FLNAFilana Therapeutics Inc. | 10 | $17 |
| ESPREsperion Therapeutics, Inc. | 6 | $16 |
| ALECAlector, Inc. | 6 | $13 |
| TRDAEntrada Therapeutics, Inc. | 1 | $13 |
| OTLKOutlook Therapeutics, Inc. | 50 | $10 |
| UPBUpstream Bio, Inc. | 1 | $9 |
| CRDFCardiff Oncology, Inc. | 5 | $8 |
| PLXProtalix BioTherapeutics, Inc. | 3 | $7 |
| FENCFENNEC PHARMACEUTICALS INC. | 1 | $6 |
| TOVXTheriva Biologics, Inc. | 11 | $2 |
| SKYESkye Bioscience, Inc. | 2 | $1 |
| ADTXAditxt, Inc. | 1 | $1 |