| GILDGILEAD SCIENCES, INC. | 416,454 | $58.0M |
| REGNREGENERON PHARMACEUTICALS, INC. | 42,909 | $33.2M |
| INSMINSMED Inc | 80,021 | $13.1M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 37,114 | $12.3M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 91,463 | $5.7M |
| INCYIncyte Corp. | 44,622 | $4.2M |
| EXELEXELIXIS, INC. | 91,477 | $3.9M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 64,517 | $3.6M |
| ONCBeOne Medicines Ltd. | 12,245 | $3.6M |
| IONSIONIS PHARMACEUTICALS INC | 44,050 | $3.3M |
| RVMDREVOLUTION MEDICINES, INC. | 31,859 | $3.1M |
| BBIOBridgeBio Pharma, Inc. | 40,161 | $3.0M |
| ARGXARGENX SE | 4,032 | $2.9M |
| MRNAModerna, Inc. | 56,087 | $2.8M |
| ABVXAbivax SA | 25,074 | $2.8M |
| AXSMAxsome Therapeutics, Inc. | 16,250 | $2.7M |
| TEVATeva Pharmaceutical Industries Limited | 79,787 | $2.4M |
| CYTKCYTOKINETICS INC | 35,139 | $2.3M |
| APLSApellis Pharmaceuticals, Inc. | 56,801 | $2.3M |
| PCVXVaxcyte, Inc. | 37,211 | $2.2M |
| PTCTPTC THERAPEUTICS, INC. | 26,379 | $1.8M |
| SRRKScholar Rock Holding Corp | 36,476 | $1.8M |
| JAZZJazz Pharmaceuticals plc | 9,215 | $1.7M |
| TGTXTG THERAPEUTICS, INC. | 49,490 | $1.6M |
| PTGXProtagonist Therapeutics, Inc | 15,280 | $1.6M |
| COGTCogent Biosciences, Inc. | 38,755 | $1.5M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 16,554 | $1.4M |
| TVTXTravere Therapeutics, Inc. | 46,118 | $1.4M |
| RDYDR REDDYS LABORATORIES LTD | 94,309 | $1.3M |
| NUVLNuvalent, Inc. | 12,649 | $1.3M |
| SMMTSummit Therapeutics Inc. | 66,402 | $1.3M |
| FOLDAMICUS THERAPEUTICS, INC. | 84,973 | $1.2M |
| ACADACADIA PHARMACEUTICALS INC | 53,804 | $1.2M |
| VKTXViking Therapeutics, Inc. | 34,892 | $1.1M |
| APGEApogee Therapeutics, Inc. | 13,418 | $1.1M |
| ARQTArcutis Biotherapeutics, Inc. | 43,234 | $1.0M |
| LQDALiquidia Corp | 24,482 | $924K |
| BEAMBeam Therapeutics Inc. | 35,884 | $855K |
| SLNOSOLENO THERAPEUTICS INC | 24,326 | $814K |
| ADMAADMA BIOLOGICS, INC. | 84,772 | $764K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 246,706 | $757K |
| NTLAIntellia Therapeutics, Inc. | 55,117 | $707K |
| OGNOrganon & Co. | 86,822 | $520K |
| SNYSanofi | 7,000 | $337K |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 5,591 | $309K |
| IMVTImmunovant, Inc. | 12,382 | $308K |
| INVAInnoviva, Inc. | 11,636 | $271K |
| DNLIDenali Therapeutics Inc. | 13,825 | $265K |
| HRMYHarmony Biosciences Holdings, Inc. | 7,720 | $216K |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 6,458 | $207K |
| IMTXImmatics N.V. | 16,583 | $163K |
| KRROKorro Bio, Inc. | 14,097 | $160K |
| KURAKura Oncology, Inc. | 14,670 | $119K |
| SIGASIGA TECHNOLOGIES INC | 20,376 | $109K |
| SPRYARS Pharmaceuticals, Inc. | 12,423 | $100K |
| GERNGERON CORP | 37,291 | $56K |
| PRQRProQR Therapeutics N.V. | 27,644 | $45K |