| ARWRARROWHEAD PHARMACEUTICALS, INC. | 3,342,493 | $209.6M |
| DNTHDianthus Therapeutics, Inc. /DE/ | 1,161,923 | $97.5M |
| COGTCogent Biosciences, Inc. | 1,239,700 | $47.7M |
| FBRXForte Biosciences, Inc. | 1,273,965 | $33.0M |
| ADPTAdaptive Biotechnologies Corp | 2,063,146 | $28.6M |
| ACADACADIA PHARMACEUTICALS INC | 1,277,151 | $28.4M |
| ROIVRoivant Sciences Ltd. | 925,186 | $25.6M |
| INSMINSMED Inc | 125,766 | $20.6M |
| PCVXVaxcyte, Inc. | 270,115 | $15.7M |
| BBIOBridgeBio Pharma, Inc. | 127,219 | $9.4M |
| NUVLNuvalent, Inc. | 81,867 | $8.4M |
| CNTACentessa Pharmaceuticals plc | 168,170 | $6.7M |
| GILDGILEAD SCIENCES, INC. | 40,756 | $5.7M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 12,597 | $4.2M |
| NKTRNEKTAR THERAPEUTICS | 53,172 | $3.8M |
| ABSIAbsci Corporation | 1,165,144 | $3.5M |
| TNGXTango Therapeutics, Inc. | 150,070 | $3.1M |
| SYRESpyre Therapeutics, Inc. | 59,453 | $3.0M |
| PVLAPALVELLA THERAPEUTICS, INC. | 21,236 | $2.6M |
| TVTXTravere Therapeutics, Inc. | 86,236 | $2.6M |
| TERNTerns Pharmaceuticals, Inc. | 47,151 | $2.5M |
| TEVATeva Pharmaceutical Industries Limited | 81,865 | $2.5M |
| ORKAOruka Therapeutics, Inc. | 43,841 | $2.2M |
| IONSIONIS PHARMACEUTICALS INC | 28,452 | $2.1M |
| SRZNSurrozen Inc. | 71,697 | $2.1M |
| RVMDREVOLUTION MEDICINES, INC. | 21,374 | $2.1M |
| KODKodiak Sciences Inc. | 48,379 | $1.8M |
| DFTXDefinium Therapeutics Inc. | 92,165 | $1.7M |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 54,195 | $1.7M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 21,626 | $1.2M |
| LGNDLigand Pharmaceuticals Incorporated | 5,689 | $1.1M |
| SLNOSOLENO THERAPEUTICS INC | 28,215 | $945K |
| TGTXTG THERAPEUTICS, INC. | 18,588 | $617K |
| CLDXCelldex Therapeutics, Inc. | 18,454 | $585K |
| QUREuniQure N.V. | 21,655 | $354K |
| EXELEXELIXIS, INC. | 5,349 | $229K |
| JAZZJazz Pharmaceuticals plc | 1,182 | $223K |
| REGNREGENERON PHARMACEUTICALS, INC. | 283 | $219K |
| INCYIncyte Corp. | 2,256 | $212K |
| BMRNBIOMARIN PHARMACEUTICAL INC | 3,690 | $208K |
| LRMRLarimar Therapeutics, Inc. | 21,267 | $96K |