| GILDGILEAD SCIENCES, INC. | 668,661 | $93.2M |
| REGNREGENERON PHARMACEUTICALS, INC. | 34,910 | $27.0M |
| VCELVericel Corp | 256,688 | $8.3M |
| LCTXLineage Cell Therapeutics, Inc. | 4,600,000 | $7.3M |
| APGEApogee Therapeutics, Inc. | 63,800 | $5.4M |
| BBIOBridgeBio Pharma, Inc. | 49,729 | $3.7M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 62,991 | $3.6M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 9,568 | $3.2M |
| MRNAModerna, Inc. | 60,341 | $3.1M |
| EXELEXELIXIS, INC. | 69,836 | $3.0M |
| INSMINSMED Inc | 18,200 | $3.0M |
| AXSMAxsome Therapeutics, Inc. | 16,214 | $2.7M |
| INCYIncyte Corp. | 27,289 | $2.6M |
| PVLAPALVELLA THERAPEUTICS, INC. | 19,947 | $2.5M |
| NUVLNuvalent, Inc. | 23,621 | $2.4M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 33,447 | $2.1M |
| CYTKCYTOKINETICS INC | 28,728 | $1.9M |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 34,137 | $1.8M |
| PTGXProtagonist Therapeutics, Inc | 13,202 | $1.4M |
| GMABGenmab A/S | 47,371 | $1.3M |
| PTCTPTC THERAPEUTICS, INC. | 17,447 | $1.2M |
| SNYSanofi | 22,916 | $1.1M |
| LGNDLigand Pharmaceuticals Incorporated | 5,501 | $1.1M |
| TGTXTG THERAPEUTICS, INC. | 31,759 | $1.1M |
| RVMDREVOLUTION MEDICINES, INC. | 9,708 | $944K |
| TEVATeva Pharmaceutical Industries Limited | 30,868 | $930K |
| APLSApellis Pharmaceuticals, Inc. | 22,102 | $889K |
| IONSIONIS PHARMACEUTICALS INC | 11,011 | $827K |
| ANIPANI PHARMACEUTICALS INC | 9,372 | $721K |
| ACADACADIA PHARMACEUTICALS INC | 31,694 | $706K |
| ADMAADMA BIOLOGICS, INC. | 55,508 | $500K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 5,260 | $457K |
| JAZZJazz Pharmaceuticals plc | 2,347 | $444K |
| RCUSArcus Biosciences, Inc. | 20,171 | $436K |
| OGNOrganon & Co. | 68,821 | $412K |
| INVAInnoviva, Inc. | 17,038 | $397K |
| SVRASavara Inc | 66,428 | $363K |
| SLSSELLAS Life Sciences Group, Inc. | 59,807 | $253K |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 4,286 | $237K |
| ANNXAnnexon, Inc. | 35,398 | $196K |
| OPKOPKO HEALTH, INC. | 128,791 | $147K |
| VKTXViking Therapeutics, Inc. | 4,086 | $133K |
| ROIVRoivant Sciences Ltd. | 4,686 | $130K |
| PCVXVaxcyte, Inc. | 2,205 | $128K |
| ARGXARGENX SE | 172 | $126K |
| SMMTSummit Therapeutics Inc. | 3,732 | $71K |
| COGTCogent Biosciences, Inc. | 1,733 | $67K |
| DFTXDefinium Therapeutics Inc. | 3,300 | $62K |
| DNLIDenali Therapeutics Inc. | 2,847 | $55K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 11,230 | $39K |
| NTLAIntellia Therapeutics, Inc. | 2,953 | $38K |
| FOLDAMICUS THERAPEUTICS, INC. | 2,593 | $37K |
| TVTXTravere Therapeutics, Inc. | 1,191 | $35K |
| TERNTerns Pharmaceuticals, Inc. | 605 | $32K |
| ADPTAdaptive Biotechnologies Corp | 1,746 | $24K |
| MIRAMIRA PHARMACEUTICALS, INC. | 20,000 | $21K |
| KURAKura Oncology, Inc. | 2,143 | $17K |
| HROWHARROW, INC. | 476 | $17K |
| DAWNDay One Biopharmaceuticals, Inc. | 774 | $17K |
| AVXLANAVEX LIFE SCIENCES CORP. | 5,113 | $16K |
| MRKRMarker Therapeutics, Inc. | 10,000 | $13K |
| QUREuniQure N.V. | 787 | $13K |
| FBRXForte Biosciences, Inc. | 496 | $13K |
| DNTHDianthus Therapeutics, Inc. /DE/ | 144 | $12K |
| BEAMBeam Therapeutics Inc. | 503 | $12K |
| SLNOSOLENO THERAPEUTICS INC | 331 | $11K |
| KALVKalVista Pharmaceuticals, Inc. | 519 | $10K |
| ARQTArcutis Biotherapeutics, Inc. | 417 | $10K |
| LQDALiquidia Corp | 224 | $8K |
| IMVTImmunovant, Inc. | 319 | $8K |
| ONCBeOne Medicines Ltd. | 25 | $7K |
| AGIOAGIOS PHARMACEUTICALS, INC. | 209 | $7K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 2,270 | $7K |
| RLAYRelay Therapeutics, Inc. | 664 | $7K |
| VRDNViridian Therapeutics, Inc.\DE | 306 | $6K |
| GERNGERON CORP | 3,776 | $6K |
| ARDXARDELYX, INC. | 924 | $6K |
| SRRKScholar Rock Holding Corp | 103 | $5K |
| AQSTAquestive Therapeutics, Inc. | 1,000 | $4K |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 4,934 | $4K |
| RDYDR REDDYS LABORATORIES LTD | 283 | $4K |
| NRIXNurix Therapeutics, Inc. | 248 | $4K |
| FLGTFulgent Genetics Inc. | 240 | $4K |
| CGTXCOGNITION THERAPEUTICS INC | 5,000 | $4K |
| BCAXBicara Therapeutics Inc. | 170 | $3K |
| ORGOOrganogenesis Holdings Inc. | 1,280 | $3K |
| GRFSGrifols S.A. | 346 | $3K |
| ORKAOruka Therapeutics, Inc. | 50 | $2K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 69 | $2K |
| ZBIOZenas BioPharma, Inc. | 107 | $2K |
| IRONDisc Medicine, Inc. | 29 | $2K |
| SPRYARS Pharmaceuticals, Inc. | 225 | $2K |
| ZYMEZymeworks Inc. | 67 | $2K |
| IBRXImmunityBio, Inc. | 216 | $2K |
| XERSXeris Biopharma Holdings, Inc. | 280 | $2K |
| ASMBASSEMBLY BIOSCIENCES, INC. | 57 | $2K |
| ESPREsperion Therapeutics, Inc. | 523 | $1K |
| RCKTRocket Pharmaceuticals Inc. | 273 | $977 |
| CLDXCelldex Therapeutics, Inc. | 31 | $969 |
| CGEMCullinan Therapeutics, Inc. | 63 | $895 |
| RNAAtrium Therapeutics Inc. | 59 | $794 |
| ABVXAbivax SA | 7 | $779 |
| LENZLENZ Therapeutics, Inc. | 79 | $723 |
| CANFCan-Fite BioPharma Ltd. | 150 | $465 |
| FDMT4D Molecular Therapeutics, Inc. | 35 | $326 |
| NUVBNuvation Bio Inc. | 74 | $319 |
| HUMAHumacyte Inc. | 500 | $303 |
| SYRESpyre Therapeutics, Inc. | 5 | $252 |
| VERUVERU INC. | 92 | $203 |
| KRROKorro Bio, Inc. | 11 | $125 |
| PBYIPUMA BIOTECHNOLOGY, INC. | 8 | $51 |
| STROSUTRO BIOPHARMA, INC. | 2 | $50 |
| BMEABiomea Fusion, Inc. | 20 | $31 |
| ALECAlector, Inc. | 6 | $13 |
| CRBPCorbus Pharmaceuticals Holdings, Inc. | 1 | $9 |
| PLRXPLIANT THERAPEUTICS, INC. | 4 | $5 |
| TVRDTvardi Therapeutics, Inc. | 1 | $3 |