| JNJJOHNSON & JOHNSON | 508,724 | $123.5M |
| LLYELI LILLY & Co | 100,859 | $89.2M |
| MDGLMADRIGAL PHARMACEUTICALS, INC. | 160,210 | $81.0M |
| GILDGILEAD SCIENCES, INC. | 547,833 | $74.8M |
| GHGuardant Health Inc. | 815,917 | $70.3M |
| ABBVAbbVie Inc. | 296,647 | $63.2M |
| AMGNAMGEN INC | 159,914 | $55.8M |
| ABTABBOTT LABORATORIES | 541,293 | $55.3M |
| PMPhilip Morris International Inc | 288,168 | $47.5M |
| MRKMerck & Co., Inc. | 390,856 | $46.3M |
| REGNREGENERON PHARMACEUTICALS, INC. | 57,209 | $42.9M |
| VRTXVERTEX PHARMACEUTICALS INC / MA | 91,958 | $40.8M |
| UNHUnitedHealth Group Incorporated Common Stock (DE) | 113,650 | $30.4M |
| PFEPFIZER INC | 691,649 | $19.2M |
| MIRMMirum Pharmaceuticals, Inc. | 210,000 | $18.5M |
| UTHRUNITED THERAPEUTICS Corp | 26,664 | $15.7M |
| REPLReplimune Group, Inc. | 2,120,000 | $15.3M |
| STOKStoke Therapeutics, Inc. | 446,000 | $14.2M |
| BBIOBridgeBio Pharma, Inc. | 189,725 | $13.2M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 36,310 | $11.5M |
| ARRYARRAY BIOPHARMA INC | 1,580,996 | $10.9M |
| ARGXARGENX SE | 14,206 | $10.0M |
| BIIBBIOGEN INC. | 53,142 | $10.0M |
| GMOptec International, Inc. | 121,690 | $8.9M |
| HALOHALOZYME THERAPEUTICS, INC. | 111,300 | $6.9M |
| INSMINSMED Inc | 41,603 | $6.4M |
| ONCBeOne Medicines Ltd. | 21,900 | $6.2M |
| MGTXMeiraGTx Holdings plc | 719,702 | $5.8M |
| ROIVRoivant Sciences Ltd. | 214,000 | $5.7M |
| BHVNBiohaven Ltd. | 693,300 | $5.6M |
| BMYBRISTOL MYERS SQUIBB CO | 92,706 | $5.5M |
| RVMDREVOLUTION MEDICINES, INC. | 59,400 | $5.5M |
| IONSIONIS PHARMACEUTICALS INC | 71,800 | $5.2M |
| ABVXAbivax SA | 50,000 | $5.1M |
| XNCRXencor Inc | 430,200 | $4.9M |
| CYTKCYTOKINETICS INC | 76,950 | $4.8M |
| MCKMcKesson Corporation | 5,137 | $4.4M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 73,000 | $4.2M |
| BNTXBioNTech SE | 47,700 | $4.1M |
| IMVTImmunovant, Inc. | 144,500 | $3.4M |
| INCYIncyte Corp. | 34,200 | $3.1M |
| PRAXPraxis Precision Medicines, Inc. | 10,500 | $2.9M |
| ACADACADIA PHARMACEUTICALS INC | 133,700 | $2.8M |
| XENEXenon Pharmaceuticals Inc. | 50,000 | $2.8M |
| NBIXNEUROCRINE BIOSCIENCES INC | 19,700 | $2.5M |
| ACLXArcellx, Inc. | 21,000 | $2.4M |
| KRYSKrystal Biotech, Inc. | 8,700 | $2.1M |
| KYMRKymera Therapeutics, Inc. | 27,000 | $2.1M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 38,520 | $2.1M |
| TERNTerns Pharmaceuticals, Inc. | 37,000 | $2.0M |
| APGEApogee Therapeutics, Inc. | 24,000 | $1.9M |
| NKTRNEKTAR THERAPEUTICS | 28,000 | $1.8M |
| AXSMAxsome Therapeutics, Inc. | 11,000 | $1.8M |
| IDXXIDEXX LABORATORIES INC /DE | 3,092 | $1.7M |
| ARQTArcutis Biotherapeutics, Inc. | 73,100 | $1.6M |
| VIRVir Biotechnology, Inc. | 180,800 | $1.5M |
| VKTXViking Therapeutics, Inc. | 47,000 | $1.4M |
| RGENREPLIGEN CORP | 12,500 | $1.4M |
| PTGXProtagonist Therapeutics, Inc | 13,500 | $1.3M |
| NUVLNuvalent, Inc. | 11,500 | $1.1M |
| MLYSMineralys Therapeutics, Inc. | 45,000 | $1.1M |
| TRVITrevi Therapeutics, Inc. | 90,000 | $1.0M |
| IMNMImmunome Inc. | 52,000 | $1.0M |
| ELVElevance Health Inc. | 3,132 | $931K |
| FOLDAMICUS THERAPEUTICS, INC. | 63,850 | $921K |
| LGNDLigand Pharmaceuticals Incorporated | 4,300 | $828K |
| OCULOCULAR THERAPEUTIX, INC | 110,000 | $814K |
| SRRKScholar Rock Holding Corp | 18,600 | $801K |
| SLNOSOLENO THERAPEUTICS INC | 25,600 | $779K |
| CORTCORCEPT THERAPEUTICS INC | 18,300 | $698K |
| ZTSZoetis Inc. | 4,496 | $523K |
| OLMAOlema Pharmaceuticals, Inc. | 38,000 | $510K |
| DNLIDenali Therapeutics Inc. | 26,900 | $486K |
| CAHCardinal Health Inc. | 2,244 | $463K |
| ADPTAdaptive Biotechnologies Corp | 35,700 | $459K |
| APLSApellis Pharmaceuticals, Inc. | 25,300 | $432K |
| GLPGGalapagos NV | 14,000 | $404K |
| CORCencora Inc. | 1,280 | $397K |
| BCRXBIOCRYST PHARMACEUTICALS INC | 40,000 | $378K |
| HRMYHarmony Biosciences Holdings, Inc. | 13,100 | $352K |
| RAREUltragenyx Pharmaceutical Inc. | 15,010 | $290K |
| ZLABZai Lab Ltd | 15,100 | $270K |
| AUTLAutolus Therapeutics plc | 195,000 | $248K |
| RLAYRelay Therapeutics, Inc. | 23,100 | $216K |
| IQVIQVIA Holdings Inc. | 1,228 | $204K |
| ABCLAbCellera Biologics Inc. | 62,000 | $203K |
| WSTWest Pharmaceutical Services Inc. | 752 | $184K |
| ZBHZimmer Biomet Holdings Inc. | 1,200 | $147K |
| RGNXREGENXBIO Inc. | 13,000 | $101K |
| ALLOAllogene Therapeutics, Inc. | 31,400 | $70K |
| TAKTakeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock) | 3,674 | $68K |
| BCYCBICYCLE THERAPEUTICS PLC | 14,000 | $61K |
| RNAAtrium Therapeutics Inc. | 3,600 | $49K |
| CSTLCastle Biosciences Inc. | 0 | $0 |
| PGNYProgyny Inc. | 0 | $0 |
| DGXQuest Diagnostics Incorporated | 0 | $0 |
| OGNOrganon & Co. | 0 | $0 |
| RDYDR REDDYS LABORATORIES LTD | 0 | $0 |