| AGIOAGIOS PHARMACEUTICALS, INC. | 2,704,900 | $80.1M |
| GILDGILEAD SCIENCES, INC. | 547,833 | $74.8M |
| REGNREGENERON PHARMACEUTICALS, INC. | 57,209 | $42.9M |
| STOKStoke Therapeutics, Inc. | 446,000 | $14.2M |
| BBIOBridgeBio Pharma, Inc. | 189,725 | $13.2M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 36,310 | $11.5M |
| DNAGinkgo Bioworks Holdings Inc. | 1,947,728 | $10.7M |
| ARGXARGENX SE | 14,206 | $10.0M |
| INSMINSMED Inc | 41,603 | $6.4M |
| ONCBeOne Medicines Ltd. | 21,900 | $6.2M |
| ROIVRoivant Sciences Ltd. | 214,000 | $5.7M |
| BHVNBiohaven Ltd. | 693,300 | $5.6M |
| RVMDREVOLUTION MEDICINES, INC. | 59,400 | $5.5M |
| IONSIONIS PHARMACEUTICALS INC | 71,800 | $5.2M |
| ABVXAbivax SA | 50,000 | $5.1M |
| CYTKCYTOKINETICS INC | 76,950 | $4.8M |
| VYGRVoyager Therapeutics, Inc. | 1,095,141 | $4.2M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 73,000 | $4.2M |
| IMVTImmunovant, Inc. | 144,500 | $3.4M |
| INCYIncyte Corp. | 34,200 | $3.1M |
| ACADACADIA PHARMACEUTICALS INC | 133,700 | $2.8M |
| EXELEXELIXIS, INC. | 52,500 | $2.2M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 38,520 | $2.1M |
| TERNTerns Pharmaceuticals, Inc. | 37,000 | $2.0M |
| APGEApogee Therapeutics, Inc. | 24,000 | $1.9M |
| NKTRNEKTAR THERAPEUTICS | 28,000 | $1.8M |
| AXSMAxsome Therapeutics, Inc. | 11,000 | $1.8M |
| ARQTArcutis Biotherapeutics, Inc. | 73,100 | $1.6M |
| VKTXViking Therapeutics, Inc. | 47,000 | $1.4M |
| PTGXProtagonist Therapeutics, Inc | 13,500 | $1.3M |
| RNACCartesian Therapeutics, Inc. | 221,705 | $1.3M |
| NUVLNuvalent, Inc. | 11,500 | $1.1M |
| FOLDAMICUS THERAPEUTICS, INC. | 63,850 | $921K |
| LGNDLigand Pharmaceuticals Incorporated | 4,300 | $828K |
| OCULOCULAR THERAPEUTIX, INC | 110,000 | $814K |
| SRRKScholar Rock Holding Corp | 18,600 | $801K |
| SLNOSOLENO THERAPEUTICS INC | 25,600 | $779K |
| OLMAOlema Pharmaceuticals, Inc. | 38,000 | $510K |
| DNLIDenali Therapeutics Inc. | 26,900 | $486K |
| ADPTAdaptive Biotechnologies Corp | 35,700 | $459K |
| APLSApellis Pharmaceuticals, Inc. | 25,300 | $432K |
| AUTLAutolus Therapeutics plc | 195,000 | $248K |
| ABCLAbCellera Biologics Inc. | 62,000 | $203K |
| RGNXREGENXBIO Inc. | 13,000 | $101K |
| BCYCBICYCLE THERAPEUTICS PLC | 14,000 | $61K |
| RNAAtrium Therapeutics Inc. | 3,600 | $49K |
| OGNOrganon & Co. | 0 | $0 |
| RDYDR REDDYS LABORATORIES LTD | 0 | $0 |