| INCYIncyte Corp. | 353,386 | $33.3M |
| GILDGILEAD SCIENCES, INC. | 195,463 | $27.2M |
| EXELEXELIXIS, INC. | 335,606 | $14.4M |
| REGNREGENERON PHARMACEUTICALS, INC. | 15,618 | $12.1M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 137,220 | $8.6M |
| INSMINSMED Inc | 51,986 | $8.5M |
| ROIVRoivant Sciences Ltd. | 285,915 | $7.9M |
| IONSIONIS PHARMACEUTICALS INC | 103,141 | $7.7M |
| APLSApellis Pharmaceuticals, Inc. | 148,038 | $6.0M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 93,504 | $5.2M |
| PTCTPTC THERAPEUTICS, INC. | 57,906 | $3.9M |
| INVAInnoviva, Inc. | 168,055 | $3.9M |
| LQDALiquidia Corp | 96,717 | $3.7M |
| AXSMAxsome Therapeutics, Inc. | 20,997 | $3.5M |
| TGTXTG THERAPEUTICS, INC. | 85,429 | $2.8M |
| JAZZJazz Pharmaceuticals plc | 14,236 | $2.7M |
| TVTXTravere Therapeutics, Inc. | 84,820 | $2.5M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 33,203 | $1.9M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 5,410 | $1.8M |
| MRNAModerna, Inc. | 33,436 | $1.7M |
| KROSKeros Therapeutics, Inc. | 145,517 | $1.6M |
| NUVLNuvalent, Inc. | 14,648 | $1.5M |
| PBYIPUMA BIOTECHNOLOGY, INC. | 204,041 | $1.3M |
| BHVNBiohaven Ltd. | 148,756 | $1.3M |
| TEVATeva Pharmaceutical Industries Limited | 37,430 | $1.1M |
| ACADACADIA PHARMACEUTICALS INC | 48,982 | $1.1M |
| PCVXVaxcyte, Inc. | 9,692 | $563K |
| LGNDLigand Pharmaceuticals Incorporated | 2,540 | $507K |
| BDTXBlack Diamond Therapeutics, Inc. | 230,177 | $490K |
| SNYSanofi | 8,858 | $427K |
| IMVTImmunovant, Inc. | 14,556 | $362K |
| VKTXViking Therapeutics, Inc. | 10,219 | $333K |
| RVMDREVOLUTION MEDICINES, INC. | 3,174 | $309K |
| ASRTAssertio Holdings, Inc. | 16,014 | $305K |
| DNLIDenali Therapeutics Inc. | 15,787 | $303K |
| NTLAIntellia Therapeutics, Inc. | 21,410 | $274K |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 5,107 | $264K |
| COGTCogent Biosciences, Inc. | 6,460 | $249K |
| FOLDAMICUS THERAPEUTICS, INC. | 16,986 | $246K |
| PTGXProtagonist Therapeutics, Inc | 2,321 | $245K |
| ARGXARGENX SE | 294 | $215K |
| OVIDOvid Therapeutics Inc. | 91,234 | $203K |
| ONCBeOne Medicines Ltd. | 676 | $201K |
| IRDOpus Genetics, Inc. | 42,065 | $191K |
| SIGASIGA TECHNOLOGIES INC | 30,316 | $162K |
| IBRXImmunityBio, Inc. | 11,689 | $90K |