| BMRNBIOMARIN PHARMACEUTICAL INC | 1,221,387 | $69.0M |
| GILDGILEAD SCIENCES, INC. | 273,107 | $38.1M |
| REGNREGENERON PHARMACEUTICALS, INC. | 43,381 | $33.5M |
| AXSMAxsome Therapeutics, Inc. | 90,088 | $15.2M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 31,427 | $10.4M |
| INSMINSMED Inc | 53,170 | $8.7M |
| TEVATeva Pharmaceutical Industries Limited | 233,895 | $7.0M |
| IRONDisc Medicine, Inc. | 96,755 | $6.2M |
| RVMDREVOLUTION MEDICINES, INC. | 36,187 | $3.5M |
| INCYIncyte Corp. | 34,157 | $3.2M |
| MRNAModerna, Inc. | 51,901 | $2.6M |
| ROIVRoivant Sciences Ltd. | 73,020 | $2.0M |
| IONSIONIS PHARMACEUTICALS INC | 19,060 | $1.4M |
| BBIOBridgeBio Pharma, Inc. | 16,841 | $1.3M |
| PCVXVaxcyte, Inc. | 19,100 | $1.1M |
| SRRKScholar Rock Holding Corp | 21,958 | $1.1M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 11,195 | $974K |
| SMMTSummit Therapeutics Inc. | 50,558 | $959K |
| CYTKCYTOKINETICS INC | 12,898 | $850K |
| VKTXViking Therapeutics, Inc. | 24,071 | $783K |
| TGTXTG THERAPEUTICS, INC. | 20,815 | $691K |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 21,558 | $690K |
| APGEApogee Therapeutics, Inc. | 7,991 | $673K |
| ARQTArcutis Biotherapeutics, Inc. | 25,401 | $598K |
| CLDXCelldex Therapeutics, Inc. | 18,087 | $574K |
| EXELEXELIXIS, INC. | 12,903 | $553K |
| JAZZJazz Pharmaceuticals plc | 2,927 | $553K |
| NUVLNuvalent, Inc. | 5,199 | $533K |
| ANNXAnnexon, Inc. | 88,617 | $491K |
| OCULOCULAR THERAPEUTIX, INC | 53,109 | $450K |
| SLNOSOLENO THERAPEUTICS INC | 13,366 | $447K |
| CNTACentessa Pharmaceuticals plc | 10,394 | $413K |
| ACADACADIA PHARMACEUTICALS INC | 18,523 | $412K |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 6,487 | $407K |
| GPCRStructure Therapeutics Inc. | 8,188 | $395K |
| QUREuniQure N.V. | 21,120 | $345K |
| VRDNViridian Therapeutics, Inc.\DE | 15,984 | $313K |
| PTCTPTC THERAPEUTICS, INC. | 4,369 | $298K |
| APLSApellis Pharmaceuticals, Inc. | 6,184 | $249K |
| PTGXProtagonist Therapeutics, Inc | 2,244 | $237K |
| LGNDLigand Pharmaceuticals Incorporated | 1,107 | $221K |
| FOLDAMICUS THERAPEUTICS, INC. | 14,662 | $212K |
| UPBUpstream Bio, Inc. | 23,515 | $212K |
| DNLIDenali Therapeutics Inc. | 10,959 | $210K |
| LENZLENZ Therapeutics, Inc. | 20,780 | $190K |
| RGNXREGENXBIO Inc. | 20,326 | $170K |
| IBRXImmunityBio, Inc. | 18,843 | $145K |
| ADMAADMA BIOLOGICS, INC. | 15,268 | $138K |
| OGNOrganon & Co. | 18,926 | $113K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 30,607 | $94K |
| GERNGERON CORP | 52,376 | $78K |
| ABUSArbutus Biopharma Corp | 14,643 | $66K |
| ATAIAtai Beckley N.V. | 13,572 | $48K |