| LLYELI LILLY & Co | 256,933 | $236.3M |
| UNHUnitedHealth Group Incorporated Common Stock (DE) | 586,928 | $158.8M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 2,817,445 | $155.5M |
| VRTXVERTEX PHARMACEUTICALS INC / MA | 251,711 | $112.4M |
| SNYSanofi | 2,223,301 | $107.1M |
| NVSNovartis AG | 505,440 | $77.2M |
| ABBVAbbVie Inc. | 348,241 | $75.7M |
| JNJJOHNSON & JOHNSON | 286,234 | $70.0M |
| BMYBRISTOL MYERS SQUIBB CO | 1,100,589 | $66.8M |
| IONSIONIS PHARMACEUTICALS INC | 874,089 | $65.6M |
| MEDPMedpace Holdings Inc. | 134,838 | $64.7M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 836,981 | $52.5M |
| MIRMMirum Pharmaceuticals, Inc. | 479,476 | $44.3M |
| RIOTRiot Platforms, Inc. | 2,635,358 | $32.6M |
| KNSAKiniksa Pharmaceuticals International, plc | 649,629 | $31.3M |
| ABTABBOTT LABORATORIES | 261,063 | $26.8M |
| REGNREGENERON PHARMACEUTICALS, INC. | 32,164 | $24.9M |
| MRKMerck & Co., Inc. | 203,676 | $24.5M |
| GHGuardant Health Inc. | 254,788 | $23.5M |
| GMOptec International, Inc. | 315,629 | $23.5M |
| AXSMAxsome Therapeutics, Inc. | 134,792 | $22.8M |
| SRPTSarepta Therapeutics, Inc. | 1,019,951 | $22.2M |
| ZTSZoetis Inc. | 187,329 | $22.1M |
| GILDGILEAD SCIENCES, INC. | 154,780 | $21.6M |
| TERNTerns Pharmaceuticals, Inc. | 384,681 | $20.3M |
| NBIXNEUROCRINE BIOSCIENCES INC | 153,755 | $20.3M |
| AMGNAMGEN INC | 49,553 | $17.4M |
| VKTXViking Therapeutics, Inc. | 516,108 | $16.8M |
| BAXBaxter International Inc. | 913,426 | $15.3M |
| AGIOAGIOS PHARMACEUTICALS, INC. | 450,093 | $15.2M |
| MDGLMADRIGAL PHARMACEUTICALS, INC. | 27,937 | $14.6M |
| TEVATeva Pharmaceutical Industries Limited | 471,891 | $14.2M |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 151,842 | $13.2M |
| DVADaVita Inc. | 81,997 | $12.6M |
| IMVTImmunovant, Inc. | 503,673 | $12.5M |
| AMLXAmylyx Pharmaceuticals, Inc. | 868,325 | $12.1M |
| FOLDAMICUS THERAPEUTICS, INC. | 747,465 | $10.8M |
| RAREUltragenyx Pharmaceutical Inc. | 500,922 | $10.5M |
| NTLAIntellia Therapeutics, Inc. | 748,636 | $9.6M |
| CRLCHARLES RIVER LABORATORIES INTERNATIONAL, INC. | 54,570 | $9.4M |
| CSTLCastle Biosciences Inc. | 377,082 | $9.3M |
| ARRYARRAY BIOPHARMA INC | 1,267,730 | $9.2M |
| ADPTAdaptive Biotechnologies Corp | 649,627 | $9.0M |
| RVMDREVOLUTION MEDICINES, INC. | 91,720 | $8.9M |
| ANABANAPTYSBIO, INC | 158,562 | $8.8M |
| KYMRKymera Therapeutics, Inc. | 104,279 | $8.7M |
| MMSIMerit Medical Systems Inc. | 124,328 | $8.6M |
| RLAYRelay Therapeutics, Inc. | 837,038 | $8.3M |
| TARSTarsus Pharmaceuticals, Inc. | 111,437 | $7.8M |
| INSMINSMED Inc | 46,230 | $7.6M |
| ELVNEnliven Therapeutics, Inc. | 191,293 | $7.5M |
| TNGXTango Therapeutics, Inc. | 355,229 | $7.4M |
| NKTRNEKTAR THERAPEUTICS | 98,745 | $7.1M |
| NEONeoGenomics Inc. | 938,052 | $7.0M |
| ORICOric Pharmaceuticals, Inc. | 522,061 | $6.6M |
| ACADACADIA PHARMACEUTICALS INC | 294,265 | $6.6M |
| KURAKura Oncology, Inc. | 800,597 | $6.5M |
| IRWDIRONWOOD PHARMACEUTICALS INC | 1,835,424 | $6.4M |
| HLFHerbalife Ltd. | 423,269 | $6.2M |
| RCUSArcus Biosciences, Inc. | 281,681 | $6.1M |
| MYGNMYRIAD GENETICS INC | 1,318,663 | $5.9M |
| IDYAIDEAYA Biosciences, Inc. | 177,272 | $5.9M |
| AUPHAurinia Pharmaceuticals Inc. | 395,405 | $5.9M |
| CLDXCelldex Therapeutics, Inc. | 184,104 | $5.8M |
| FULCFulcrum Therapeutics, Inc. | 736,684 | $5.7M |
| MCKMcKesson Corporation | 6,316 | $5.5M |
| EBSEmergent BioSolutions Inc. | 648,377 | $5.4M |
| ACRSAclaris Therapeutics, Inc. | 1,418,360 | $5.3M |
| RDYDR REDDYS LABORATORIES LTD | 382,976 | $5.3M |
| COGTCogent Biosciences, Inc. | 136,450 | $5.3M |
| TVTXTravere Therapeutics, Inc. | 176,390 | $5.2M |
| NUVBNuvation Bio Inc. | 1,207,771 | $5.2M |
| NUVLNuvalent, Inc. | 50,026 | $5.1M |
| PBYIPUMA BIOTECHNOLOGY, INC. | 782,798 | $5.0M |
| FLGTFulgent Genetics Inc. | 302,564 | $4.8M |
| CORTCORCEPT THERAPEUTICS INC | 117,954 | $4.8M |
| WVEWave Life Sciences Ltd. | 624,735 | $4.5M |
| CGEMCullinan Therapeutics, Inc. | 289,115 | $4.1M |
| TBPHTheravance Biopharma, Inc. | 249,755 | $4.1M |
| PFEPFIZER INC | 129,710 | $3.6M |
| SDGRSchrodinger, Inc. | 310,728 | $3.5M |
| ACHAccendra Health Inc. | 1,380,728 | $3.1M |
| NATRNATURES SUNSHINE PRODUCTS INC | 125,533 | $3.0M |
| CRNXCrinetics Pharmaceuticals, Inc. | 79,755 | $2.9M |
| PTGXProtagonist Therapeutics, Inc | 27,260 | $2.9M |
| KROSKeros Therapeutics, Inc. | 257,884 | $2.8M |
| HRMYHarmony Biosciences Holdings, Inc. | 101,110 | $2.8M |
| NUSNu Skin Enterprises Inc. | 366,016 | $2.7M |
| CMPXCompass Therapeutics, Inc. | 497,818 | $2.6M |
| NAGENiagen Bioscience, Inc. | 582,448 | $2.6M |
| MGNXMACROGENICS INC | 867,249 | $2.5M |
| JBIOJade Biosciences, Inc. | 169,051 | $2.4M |
| XERSXeris Biopharma Holdings, Inc. | 407,625 | $2.4M |
| PRAXPraxis Precision Medicines, Inc. | 7,194 | $2.3M |
| BDTXBlack Diamond Therapeutics, Inc. | 1,058,397 | $2.3M |
| RIGLRIGEL PHARMACEUTICALS INC | 83,129 | $2.2M |
| IMRXImmuneering Corp | 400,363 | $2.1M |
| TECXTectonic Therapeutic, Inc. | 66,994 | $2.1M |
| ZNTLZentalis Pharmaceuticals, Inc. | 792,001 | $1.9M |
| NVONovo Nordisk A/S | 46,923 | $1.7M |
| JANXJanux Therapeutics, Inc. | 119,376 | $1.7M |
| ENTAENANTA PHARMACEUTICALS INC | 125,759 | $1.6M |
| PRTAPROTHENA CORP PUBLIC LTD CO | 156,551 | $1.5M |
| DGXQuest Diagnostics Incorporated | 7,179 | $1.4M |
| ARVNARVINAS, INC. | 131,974 | $1.4M |
| ZVRAZEVRA THERAPEUTICS, INC. | 145,222 | $1.4M |
| PRGOPERRIGO Co plc | 121,733 | $1.3M |
| CRVSCorvus Pharmaceuticals, Inc. | 83,907 | $1.2M |
| XENEXenon Pharmaceuticals Inc. | 19,439 | $1.1M |
| OLMAOlema Pharmaceuticals, Inc. | 70,711 | $1.1M |
| ETONEton Pharmaceuticals, Inc. | 42,693 | $1.1M |
| LGNDLigand Pharmaceuticals Incorporated | 4,943 | $987K |
| APGEApogee Therapeutics, Inc. | 11,481 | $966K |
| ZYMEZymeworks Inc. | 37,919 | $949K |
| CORCencora Inc. | 2,973 | $934K |
| ELANElanco Animal Health Inc | 38,406 | $919K |
| ALHCAlignment Healthcare Inc. | 46,928 | $827K |
| NPCENeuropace Inc. | 56,834 | $747K |
| ERASErasca, Inc. | 45,338 | $734K |
| CCCCC4 Therapeutics, Inc. | 277,183 | $729K |
| RGNXREGENXBIO Inc. | 85,248 | $714K |
| NRIXNurix Therapeutics, Inc. | 44,976 | $697K |
| SVRASavara Inc | 122,862 | $671K |
| REPLReplimune Group, Inc. | 86,910 | $665K |
| AGENAGENUS INC | 198,502 | $663K |
| PLRXPLIANT THERAPEUTICS, INC. | 517,453 | $652K |
| KRMDKORU Medical Systems Inc. Common Stock (DE) | 140,743 | $608K |
| ASMBASSEMBLY BIOSCIENCES, INC. | 21,761 | $604K |
| OPKOPKO HEALTH, INC. | 522,906 | $596K |
| FATEFATE THERAPEUTICS INC | 469,785 | $564K |
| USNAUSANA HEALTH SCIENCES INC | 30,061 | $525K |
| ANNXAnnexon, Inc. | 92,707 | $514K |
| PLXProtalix BioTherapeutics, Inc. | 207,275 | $450K |
| KPTIKaryopharm Therapeutics Inc. | 79,081 | $440K |
| AKBAAkebia Therapeutics, Inc. | 274,431 | $381K |
| PRLDPrelude Therapeutics Inc | 109,085 | $373K |
| LENZLENZ Therapeutics, Inc. | 37,314 | $341K |
| ANIKAnika Therapeutics Inc. | 22,736 | $330K |
| ANIPANI PHARMACEUTICALS INC | 4,225 | $325K |
| CAHCardinal Health Inc. | 1,496 | $316K |
| LRMRLarimar Therapeutics, Inc. | 69,087 | $311K |
| ALLOAllogene Therapeutics, Inc. | 113,964 | $278K |
| WSTWest Pharmaceutical Services Inc. | 988 | $248K |
| FLNAFilana Therapeutics Inc. | 136,931 | $231K |
| GOSSGossamer Bio, Inc. | 658,221 | $216K |
| SIGASIGA TECHNOLOGIES INC | 36,064 | $193K |
| ORMPORAMED PHARMACEUTICALS INC. | 50,207 | $171K |
| AGLagilon health inc. | 20,283 | $160K |
| PEPGPepGen Inc. | 69,123 | $122K |
| ABUSArbutus Biopharma Corp | 25,859 | $116K |
| KLRSKalaris Therapeutics, Inc. | 13,655 | $79K |
| AVIRAtea Pharmaceuticals, Inc. | 12,985 | $70K |
| AVXLANAVEX LIFE SCIENCES CORP. | 19,655 | $60K |
| CRBUCaribou Biosciences, Inc. | 30,741 | $58K |
| PMVPPMV Pharmaceuticals, Inc. | 32,460 | $40K |
| OABIOmniAb Inc. | 14,136 | $22K |