| GILDGILEAD SCIENCES, INC. | 270,352 | $37.7M |
| REGNREGENERON PHARMACEUTICALS, INC. | 43,972 | $34.0M |
| INCYIncyte Corp. | 226,501 | $21.3M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 263,389 | $14.9M |
| OGNOrganon & Co. | 2,309,039 | $13.8M |
| EXELEXELIXIS, INC. | 313,945 | $13.5M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 181,753 | $10.0M |
| JAZZJazz Pharmaceuticals plc | 45,746 | $8.6M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 20,256 | $6.7M |
| SNYSanofi | 133,553 | $6.4M |
| ADPTAdaptive Biotechnologies Corp | 445,588 | $6.2M |
| GRCEGrace Therapeutics, Inc. | 849,055 | $3.9M |
| INSMINSMED Inc | 21,484 | $3.5M |
| TEVATeva Pharmaceutical Industries Limited | 85,414 | $2.6M |
| RDYDR REDDYS LABORATORIES LTD | 181,595 | $2.5M |
| SMMTSummit Therapeutics Inc. | 113,786 | $2.2M |
| KNSAKiniksa Pharmaceuticals International, plc | 43,712 | $2.1M |
| ARGXARGENX SE | 2,788 | $2.0M |
| MRNAModerna, Inc. | 37,150 | $1.9M |
| VCELVericel Corp | 56,916 | $1.8M |
| ROIVRoivant Sciences Ltd. | 62,322 | $1.7M |
| RVMDREVOLUTION MEDICINES, INC. | 17,663 | $1.7M |
| BBIOBridgeBio Pharma, Inc. | 20,595 | $1.5M |
| HRMYHarmony Biosciences Holdings, Inc. | 48,283 | $1.4M |
| LRMRLarimar Therapeutics, Inc. | 247,912 | $1.1M |
| GMABGenmab A/S | 39,702 | $1.1M |
| BHVNBiohaven Ltd. | 112,825 | $954K |
| AXSMAxsome Therapeutics, Inc. | 5,385 | $910K |
| FOLDAMICUS THERAPEUTICS, INC. | 58,090 | $840K |
| KURAKura Oncology, Inc. | 101,022 | $821K |
| PTCTPTC THERAPEUTICS, INC. | 10,856 | $740K |
| ONCBeOne Medicines Ltd. | 2,158 | $641K |
| PTGXProtagonist Therapeutics, Inc | 5,693 | $600K |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 9,450 | $593K |
| IONSIONIS PHARMACEUTICALS INC | 7,596 | $570K |
| INVAInnoviva, Inc. | 24,327 | $567K |
| KODKodiak Sciences Inc. | 14,869 | $567K |
| ARQTArcutis Biotherapeutics, Inc. | 23,926 | $564K |
| RGNXREGENXBIO Inc. | 58,377 | $489K |
| ARDXARDELYX, INC. | 68,765 | $412K |
| SRRKScholar Rock Holding Corp | 8,231 | $405K |
| NUVBNuvation Bio Inc. | 93,963 | $403K |
| CYTKCYTOKINETICS INC | 6,048 | $399K |
| DAWNDay One Biopharmaceuticals, Inc. | 18,197 | $390K |
| ACADACADIA PHARMACEUTICALS INC | 15,772 | $351K |
| ADMAADMA BIOLOGICS, INC. | 38,147 | $344K |
| PCVXVaxcyte, Inc. | 5,630 | $327K |
| ANIPANI PHARMACEUTICALS INC | 4,116 | $317K |
| TVTXTravere Therapeutics, Inc. | 9,883 | $294K |
| NTLAIntellia Therapeutics, Inc. | 22,532 | $289K |
| RCKTRocket Pharmaceuticals Inc. | 78,974 | $283K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 3,215 | $280K |
| DNLIDenali Therapeutics Inc. | 12,658 | $243K |
| RLAYRelay Therapeutics, Inc. | 24,195 | $241K |
| DRTSAlpha Tau Medical Ltd. | 32,012 | $226K |
| NRIXNurix Therapeutics, Inc. | 13,328 | $207K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 63,919 | $196K |
| ABCLAbCellera Biologics Inc. | 52,299 | $183K |
| CTMXCytomX Therapeutics, Inc. | 37,806 | $178K |
| XERSXeris Biopharma Holdings, Inc. | 30,583 | $177K |
| LXRXLEXICON PHARMACEUTICALS, INC. | 110,458 | $172K |
| GRFSGrifols S.A. | 21,360 | $171K |
| ORGOOrganogenesis Holdings Inc. | 62,909 | $149K |
| ALDXAldeyra Therapeutics, Inc. | 81,223 | $137K |
| FATEFATE THERAPEUTICS INC | 113,544 | $136K |
| SANASana Biotechnology, Inc. | 40,183 | $116K |
| PRLDPrelude Therapeutics Inc | 32,875 | $112K |
| IVAInventiva S.A. | 20,000 | $111K |
| ANNXAnnexon, Inc. | 17,979 | $100K |
| IBRXImmunityBio, Inc. | 12,085 | $93K |
| PBYIPUMA BIOTECHNOLOGY, INC. | 13,013 | $83K |
| PGENPRECIGEN, INC. | 21,250 | $82K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 19,387 | $68K |
| BCYCBICYCLE THERAPEUTICS PLC | 13,570 | $63K |
| LSTALISATA THERAPEUTICS, INC. | 12,183 | $61K |
| CHRSCoherus Oncology, Inc. | 35,968 | $61K |
| RZLTRezolute, Inc. | 19,923 | $61K |
| ALECAlector, Inc. | 26,976 | $58K |
| SIGASIGA TECHNOLOGIES INC | 10,788 | $58K |
| CMPSCOMPASS Pathways plc | 10,204 | $56K |
| CNTXContext Therapeutics Inc. | 20,000 | $52K |
| AVXLANAVEX LIFE SCIENCES CORP. | 14,170 | $44K |
| SGMOQSANGAMO THERAPEUTICS, INC | 163,943 | $40K |
| HUMAHumacyte Inc. | 48,100 | $29K |
| ESPREsperion Therapeutics, Inc. | 10,063 | $28K |
| OPKOPKO HEALTH, INC. | 23,471 | $27K |
| HURATuHURA Biosciences, Inc./NV | 14,860 | $27K |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 17,243 | $14K |
| ONCYONCOLYTICS BIOTECH INC | 10,000 | $8K |