Skip to main content

varenicline

Generic: VARENICLINE TARTRATE·Brand: CHANTIX, Chantix, TYRVAYA, Tyrvaya, VARENICLINE TARTRATE

varenicline: developed by 1 company · 8 clinical trials tracked · 1 FDA decision.

varenicline evidence translation

What we can confirm

1 FDA record · 8 tracked trials

What it means

Source-backed records connect varenicline to RDY; that link alone does not prove the drug works.

What to watch

Watch active trials and any change in FDA or trial status.
BioSniper AIPage evidence connected

Prepared research question

How could varenicline → RDY affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 3 study sponsors
Development Pipeline (1)
CompanyPhase
DR REDDYS LABORATORIES LTD (RDY)Approved
Clinical Trials (8)

Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness

Not yet recruiting

Primary endpoint: Number of participants whose self-report of prolonged smoking abstinence is bioverified

InterventionalRandomizedopen120 targetStarted 2027-03Completion 2030-091 site · United StatesVA Office of Research and Development

A Phase 1/2, Multicenter, Open-Label Study to Evaluate Safety, Tolerability, and PRELIminary EFficacy of Percutaneous Injection of RP-008 Followed by Daily Oral Varenicline in Patients With Trigeminal Neuralgia (The RELIEF Study)

NCT07596485·Phase 1/Phase 2·RLFTF
Recruiting

Primary endpoint: Incidence and severity of adverse events, abnormal clinical laboratory values, abnormal physical examinations, abnormal vital signs, abnormal electrocardiograms (ECGs), and suicidal ideation

Interventionalopen24 targetStarted 2026-08Completion 2029-021 site · CanadaKriya Therapeutics, Inc.

Randomized Factorial Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention to Promote Smoking Cessation

NCT07099638·Phase 2·MRUS
Not yet recruiting

Primary endpoint: Smoking Abstinence (26 weeks post-quit)

InterventionalRandomizedopen496 targetStarted 2026-03Completion 2029-061 site · United StatesUniversity of Oklahoma

Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes

Recruiting

Primary endpoint: Change in cigarettes smoked per day (CPD)

InterventionalRandomizedsingle400 targetStarted 2024-04Completion 2027-031 site · United StatesMontefiore Medical Center

Evaluating Smoking Cessation Interventions for PWH in South Africa: Efficacy, Implementation, and Cost-effectiveness

NCT05413122·Phase 2/Phase 3
Recruiting

Primary endpoint: 7-day point prevalence tobacco abstinence at 52 weeks

InterventionalRandomizedopen660 targetStarted 2023-11Completion 2027-081 site · South AfricaJohns Hopkins University

A Translational Randomized Clinical Trial of Varenicline Sampling to Promote Smoking Cessation and Scalable Treatment Dissemination

NCT04525755·Phase 1·MRUS
Completed

Primary endpoint: Smoking Cessation

InterventionalRandomizedopen652 enrolledStarted 2021-02Completion 2025-041 site · United StatesMedical University of South Carolina

Smoking Cessation Treatment for Head & Neck Cancer Patients: Acceptance and Commitment Therapy

NCT01098955·Early Phase 1
Active, not recruiting

Primary endpoint: Smoking Abstinence Rate

InterventionalRandomizedopen51 targetStarted 2010-03Completion 2027-091 site · United StatesM.D. Anderson Cancer Center

Varenicline Versus Transdermal Nicotine Patch for Smoking Cessation in Patients With Coronary Heart Disease: a Pilot Randomized Trial

NCT00959972·Phase 4
Completed

Primary endpoint: The primary outcome will be the self-reported continuous abstinence rate, confirmed by exhaled carbon monoxide levels of 10ppm or below during the last 4 weeks of treatment (Varenicline weeks 9-12 and NRT weeks 8-11).

InterventionalRandomizedopen50 enrolledStarted 2009-04Completion 2010-111 site · CanadaOttawa Heart Institute Research Corporation
FDA Decisions1 records
Approval1 INDICATIONS AND USAGE Varenicline tablets are indicated for use as an aid to smoking cessation treatment. Varenicline tablets are nicotinic receptor partial agonist indicated for use as an aid to smoking cessation treatment. ( 1 and 2.1 )(RDY)FDA ↗
ANDA215931UNKNOWNStandardOralTablet

Frequently asked questions

Who is developing varenicline?

varenicline is being developed by DR REDDYS LABORATORIES LTD.

How many clinical trials involve varenicline?

BioSniper tracks 8 clinical trials involving varenicline.

What is varenicline's latest FDA decision?

The most recent tracked FDA decision for varenicline is Approval for 1 INDICATIONS AND USAGE Varenicline tablets are indicated for use as an aid to smoking cessation treatment. Varenicline tablets are nicotinic receptor partial agonist indicated for use as an aid to smoking cessation treatment. ( 1 and 2.1 ), dated October 1, 2024.