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nicotine

Generic: NICOTINE·Brand: HABITROL, NICODERM CQ, NICOTINE, NICOTROL, PROSTEP

nicotine: 9 clinical trials tracked.

nicotine evidence translation

What we can confirm

9 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about nicotine, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 0 study sponsors

Study sponsors

No additional listed-company sponsor is linked.

Clinical Trial Registry Records (9)

Providing Nicotine Replacement Therapy to Enhance the Efficacy of a Smoking Cessation Smartphone App for Hispanic Adults

NCT06811038Registry updated 2026-06-09·Phase 3
Not yet recruiting

Primary endpoint: 30-day point prevalence abstinence (PPA)

InterventionalRandomizedquadruple854 targetStarted 2026-08Completion 2030-071 site · United StatesFred Hutchinson Cancer Center

Comparative Evaluation of Nicotine Analogs

NCT07585006Registry updated 2026-05-29·Phase 1
Not yet recruiting

Primary endpoint: Nicotine urges/craving (QSU)

InterventionalRandomizedsingle70 targetStarted 2026-06Completion 2026-121 site · United StatesOhio State University Comprehensive Cancer Center

Evaluating Smoking Cessation Interventions for PWH in South Africa: Efficacy, Implementation, and Cost-effectiveness

NCT05413122Registry updated 2026-06-09·Phase 2/Phase 3
Recruiting

Primary endpoint: 7-day point prevalence tobacco abstinence at 52 weeks

InterventionalRandomizedopen660 targetStarted 2023-11Completion 2027-081 site · South AfricaJohns Hopkins University

Effectiveness of Nicotine Replacement Therapy Sampling in Dental Practices

NCT05627596Registry updated 2026-07-24·Phase 2
Completed

Primary endpoint: 7-day Biochemically Confirmed Point Prevalence Abstinence

InterventionalRandomizedopen1,239 enrolledStarted 2023-06Completion 2025-061 site · United StatesSandra Japuntich

Ending Tobacco Use Through Interactive Tailored Messaging for Cambodian People Living With HIV/AIDS (Project END-IT)

NCT05746442Registry updated 2026-08-13·N/A
Recruiting

Primary endpoint: Self Reported 7 Day Abstinence Smoking Status

InterventionalRandomizedsingle800 targetStarted 2023-01Completion 2027-093 sites · CambodiaH. Lee Moffitt Cancer Center and Research Institute

Randomized Trial of Automated Video-Assisted Smoking Treatment for People Living With HIV (Project RESOURCE)

NCT05014282Registry updated 2026-09-25·N/A
Active, not recruiting

Primary endpoint: Self-Reported 7-Day Point-Prevalence Smoking Abstinence

InterventionalRandomizedopen512 enrolledStarted 2021-12Completion 2026-091 site · United StatesH. Lee Moffitt Cancer Center and Research Institute

Partnering With a State Food Bank to Provide Tobacco Treatment to Underserved Smokers (Project NOURISH)

NCT05004662Registry updated 2026-09-24·N/A
Completed

Primary endpoint: Self-Reported 7-Day Point-Prevalence Smoking Abstinence

InterventionalRandomizedopen502 enrolledStarted 2021-12Completion 2025-081 site · United StatesH. Lee Moffitt Cancer Center and Research Institute

Long-Term Nicotine Treatment of Mild Cognitive Impairment

NCT02720445Registry updated 2026-09-17·Phase 2
Completed

Primary endpoint: Cogstate Battery International Shopping List Test - Total Immediate Recall (ISLT-TIR)

InterventionalRandomizedquadruple348 enrolledStarted 2017-02Completion 2025-0936 sites · United StatesUniversity of Southern California

Low Reward Sensitivity and Behavioral Activation Therapy for Smoking Cessation

NCT02697227Registry updated 2026-06-11·N/A
Active, not recruiting

Primary endpoint: Effectiveness of behavioral activation treatment for smoking plus nicotine replacement therapy versus standard cessation treatment plus nicotine replacement therapy defined as abstinence rate in low reward sensitivity- and + smokers

InterventionalRandomizeddouble85 targetStarted 2016-08Completion 2027-121 site · United StatesM.D. Anderson Cancer Center