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nicotine

Generic: NICOTINE·Brand: HABITROL, NICODERM CQ, NICOTINE, NICOTROL, PROSTEP

nicotine: 9 clinical trials tracked.

nicotine evidence translation

What we can confirm

9 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about nicotine, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 0 study sponsors

Study sponsors

No additional listed-company sponsor is linked.

Clinical Trials (9)

Providing Nicotine Replacement Therapy to Enhance the Efficacy of a Smoking Cessation Smartphone App for Hispanic Adults

NCT06811038·Phase 3
Not yet recruiting

Primary endpoint: 30-day point prevalence abstinence (PPA)

InterventionalRandomizedquadruple854 targetStarted 2026-08Completion 2030-071 site · United StatesFred Hutchinson Cancer Center

Comparative Evaluation of Nicotine Analogs

NCT07585006·Phase 1
Not yet recruiting

Primary endpoint: Nicotine urges/craving (QSU)

InterventionalRandomizedsingle70 targetStarted 2026-06Completion 2026-121 site · United StatesOhio State University Comprehensive Cancer Center

Evaluating Smoking Cessation Interventions for PWH in South Africa: Efficacy, Implementation, and Cost-effectiveness

NCT05413122·Phase 2/Phase 3
Recruiting

Primary endpoint: 7-day point prevalence tobacco abstinence at 52 weeks

InterventionalRandomizedopen660 targetStarted 2023-11Completion 2027-081 site · South AfricaJohns Hopkins University

Effectiveness of Nicotine Replacement Therapy Sampling in Dental Practices

NCT05627596·Phase 2
Completed

Primary endpoint: 7-day Biochemically Confirmed Point Prevalence Abstinence

InterventionalRandomizedopen1,239 enrolledStarted 2023-06Completion 2025-061 site · United StatesSandra Japuntich

Ending Tobacco Use Through Interactive Tailored Messaging for Cambodian People Living With HIV/AIDS (Project END-IT)

Recruiting

Primary endpoint: Self Reported 7 Day Abstinence Smoking Status

InterventionalRandomizedsingle800 targetStarted 2023-01Completion 2027-093 sites · CambodiaH. Lee Moffitt Cancer Center and Research Institute

Randomized Trial of Automated Video-Assisted Smoking Treatment for People Living With HIV (Project RESOURCE)

Primary endpoint: Self Reported 7 Day Abstinence Smoking Status

InterventionalRandomizedopen638 targetStarted 2021-12Completion 2026-091 site · United StatesH. Lee Moffitt Cancer Center and Research Institute

Partnering With a State Food Bank to Provide Tobacco Treatment to Underserved Smokers (Project NOURISH)

Completed

Primary endpoint: Self-Reported 7-Day Point-Prevalence Smoking Abstinence

InterventionalRandomizedopen502 enrolledStarted 2021-12Completion 2025-081 site · United StatesH. Lee Moffitt Cancer Center and Research Institute

Long-Term Nicotine Treatment of Mild Cognitive Impairment

NCT02720445·Phase 2
Completed

Primary endpoint: Cogstate Battery International Shopping List Test - Total Immediate Recall (ISLT-TIR)

InterventionalRandomizedquadruple348 enrolledStarted 2017-01Completion 2025-0936 sites · United StatesUniversity of Southern California

Low Reward Sensitivity and Behavioral Activation Therapy for Smoking Cessation

Active, not recruiting

Primary endpoint: Effectiveness of behavioral activation treatment for smoking plus nicotine replacement therapy versus standard cessation treatment plus nicotine replacement therapy defined as abstinence rate in low reward sensitivity- and + smokers

InterventionalRandomizeddouble85 targetStarted 2016-08Completion 2027-121 site · United StatesM.D. Anderson Cancer Center