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toripalimab

Generic: toripalimab·Brand: Loqtorzi

toripalimab: 25 clinical trials tracked.

toripalimab evidence translation

What we can confirm

25 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about toripalimab, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 1 study sponsors
Clinical Trial Registry Records (25)showing 10 most recent

A Phase II Study of Induction/Window of Opportunity Toripalimab Followed by Definitive Chemoradiotherapy (CRT) and Adjuvant Toripalimab for Patients With Locally Advanced Esophageal Squamous Cell Carcinoma (ESCC)

NCT07836049Registry updated 2026-09-23·Phase 2
Not yet recruiting

Primary endpoint: To determine the clinical complete response rate to proportion of patients with complete clinical response (cCR) 4-12 weeks after completion of standard-of-care (SOC) dCRT.

Interventionalopen20 targetStarted 2026-12Completion 2031-121 site · United StatesVanderbilt-Ingram Cancer Center

Master Protocol for A Phase 1b/2 Study of Neoadjuvant Immunotherapy in Microsatellite Stable (MSS) Colorectal Cancer (CRC) Subjects With Resectable Liver Metastases

NCT07277322Registry updated 2026-08-12·Phase 1/Phase 2
Recruiting

Primary endpoint: Number of dose limiting toxicities (DLTs)

Interventionalopen24 targetStarted 2026-09Completion 2030-121 site · United StatesDan Feng

A Combination Therapy Strategy to Prevent Anti-PD-1 Therapy Resistance in Metastatic Ovarian Cancer Patients

NCT05479045Registry updated 2026-10-09·Phase 2
Withdrawn

Primary endpoint: Median Progression Free Survival

Interventionalopen0 enrolledStarted 2026-09Completion 2028-11Georgetown University

REMEDY-RCC: Gut Microbiota Modulation for Immunotherapy Resensitization in Advanced Renal Cell Carcinoma - A Prospective, Exploratory, Single-Center Study

NCT07611825Registry updated 2026-05-28·Phase 2
Not yet recruiting

Primary endpoint: Objective Response Rate(ORR)

Interventionalopen33 targetStarted 2026-06Completion 2028-121 site · ChinaJinling Hospital, China

A Phase I/II Multicenter, Non-randomized, Open-label, Dose Escalation and Expansion Study of IPG7236 Combined With Toripalimab Treatment of Advanced Solid Tumors in Adult Patients to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity

NCT07508761Registry updated 2026-04-02·Phase 1/Phase 2
Not yet recruiting

Primary endpoint: Incidence of Dose-Limiting Toxicity (DLT)

Interventionalopen52 targetStarted 2026-05Completion 2029-071 site · ChinaNanjing Immunophage Biotech Co., Ltd

A Phase II Window of Opportunity in Preserving Laryngeal Function (WOLF) Trial

NCT07423078Registry updated 2026-04-13·Phase 2
Recruiting

Primary endpoint: 1-Year Disease-free survival (DFS)

Interventionalopen87 targetStarted 2026-04Completion 2031-041 site · United StatesMatthew Spector

A Phase 2 Study of Toripalimab in Combination With Cisplatin and Docetaxel (PDT) for Induction Therapy in CPS-Positive Locally Advanced Head and Neck Squamous Cell Carcinoma

NCT07214987Registry updated 2026-07-14·Phase 2
Recruiting

Primary endpoint: Proportion Grade 3-5 TRAE-free during induction therapy

Interventionalopen26 targetStarted 2026-03Completion 2029-092 sites · United StatesMassachusetts General Hospital

Neoadjuvant Chemotherapy and PD-1 Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

NCT07209189Registry updated 2026-03-09·Phase 2
Recruiting

Primary endpoint: Major Pathological Response (MPR)

Interventionalopen75 targetStarted 2026-03Completion 2030-121 site · United StatesSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase II Exploratory Study of Toripalimab Combined With Stereotactic Body Radiation Therapy in HER2-Negative Breast Cancer Patients With Insensitivity to Neoadjuvant Chemotherapy

NCT07410234Registry updated 2026-02-13·Phase 2
Not yet recruiting

Primary endpoint: Pathologic complete response(pCR)

InterventionalRandomizedopen110 targetStarted 2026-02Completion 2029-02Tianjin Medical University Cancer Institute and Hospital

Phase II Trial of Neoadjuvant Toripalimab in Combination With Chemotherapy Followed by Transoral Robotic Surgery or Risk/Response Stratified Chemoradiotherapy for Locoregional HPV16+ Oropharyngeal Cancer: TARGET HPV Cohort 2

NCT07290621Registry updated 2026-02-06·Phase 2
Recruiting

Primary endpoint: Deep Response Rate (DRR) with toripalimab + chemotherapy

Interventionalopen30 targetStarted 2026-02Completion 2033-021 site · United StatesUniversity of Chicago