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dupilumab

Generic: dupilumab·Brand: Dupixent

dupilumab: 66 clinical trials tracked.

dupilumab evidence translation

What we can confirm

66 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about dupilumab, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 9 study sponsors
Clinical Trials (66)showing 10 most recent

An Open-Label, Expanded Access Program of Dupilumab in Adult Patients With Bullous Pemphigoid

Approved for marketing
Expanded AccessRegeneron Pharmaceuticals

An Open Label, Expanded Access Program of Dupilumab in Adults With Severe IgE-Mediated Food Allergy Who Have Been Previously Treated With Linvoseltamab and Background Dupilumab

Available
Expanded AccessRegeneron Pharmaceuticals

Master Protocol for A Phase 1b/2 Study of Neoadjuvant Immunotherapy in Microsatellite Stable (MSS) Colorectal Cancer (CRC) Subjects With Resectable Liver Metastases

NCT07277322·Phase 1/Phase 2
Recruiting

Primary endpoint: Number of dose limiting toxicities (DLTs)

Interventionalopen24 targetStarted 2026-09Completion 2030-121 site · United StatesDan Feng

A Randomized, Double-Blind, Placebo-Controlled Study Comparing the Efficacy of Dupilumab Added on to Standard of Care (SOC) Treatment vs SOC Treatment Following Hospitalization for a COPD Exacerbation

NCT07587658·Phase 4
Not yet recruiting

Primary endpoint: Time to first all-cause event

InterventionalRandomizedquadruple754 targetStarted 2026-06Completion 2028-07Regeneron Pharmaceuticals

Phase 1, Single Center, Open-label, Randomized, Parallel-group Study to Evaluate Pharmacokinetics and Tolerability of a Single Subcutaneous Dose of Dupilumab Coformulated With Berahyaluronidase Alfa and Dupilumab Without Berahyaluronidase Alfa in Healthy Participants

NCT07646548·Phase 1·SNY
Active, not recruiting

Primary endpoint: Pharmacokinetic (PK) parameter in serum: Cmax of dupilumab

InterventionalRandomizedopen40 targetStarted 2026-06Completion 2026-091 site · United StatesSanofi

A Prospective Observational Study of Patients Receiving Dupilumab for Chronic Spontaneous Urticaria

Terminated

Primary endpoint: Summary of Sociodemographic Characteristics

Observational1 enrolledStarted 2026-03Completion 2026-061 site · United StatesSanofi

The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatitis in Gulf Countries

Recruiting

Primary endpoint: Proportion of Participants with Hospital Anxiety and Depression Scale Anxiety (HADS-A) Sub-scores of Less Than 8

Observational184 targetStarted 2026-02Completion 2027-057 sites · Qatar, Saudi Arabia, United Arab EmiratesSanofi

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Proof-of-Concept Study to Evaluate the Efficacy and Safety of IBI3002 in Patients With Moderate to Severe Atopic Dermatitis

NCT07399067·Phase 2·CRNX
Recruiting

Primary endpoint: Percentage change from baseline in the Eczema Area and Severity Index (EASI) score at Week 16

InterventionalRandomizedquadruple120 targetStarted 2026-02Completion 2027-051 site · ChinaInnovent Biologics (Suzhou) Co. Ltd.

A Multinational, Investigator-initiated, Parallel Group, Randomised, Double-blind, Placebo-controlled Phase 3b Superiority Trial Assessing the Effect of Dupilumab on Inducing Clinical Remission Outcomes in At-risk Type-2 Inflammatory Asthma (HOTHOT)

NCT07309614·Phase 3
Recruiting

Primary endpoint: Win ratio based on remission criteria

InterventionalRandomizedquadruple150 targetStarted 2026-01Completion 2030-015 sites · Australia, Canada, United KingdomUniversité de Sherbrooke

An Open-Label, Single-Arm Study to Assess Growth and Bone Mineral Density in Children ≥6 to <12 Years of Age With Severe Atopic Dermatitis Treated With Dupilumab

NCT07187089·Phase 4
Withdrawn

Primary endpoint: Improvement of ≥5 percentile in height-for-age percentile on the Centers for Disease Control and Prevention (CDC) growth chart

Interventionalopen0 targetStarted 2025-11Completion 2028-01Regeneron Pharmaceuticals