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tipifarnib

tipifarnib: developed by 1 company · 2 clinical trials tracked.

tipifarnib evidence translation

What we can confirm

What it means

Source-backed records connect tipifarnib to KURA; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could tipifarnib → KURA affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 0 study sponsors

Related indications

HNSCC; HRAS Mutations or Peripheral T Cell Lymphoma (PTCL)

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
Kura Oncology, Inc. (KURA)
HNSCC; HRAS Mutations or Peripheral T Cell Lymphoma (PTCL)
Phase 1/Phase 2
Clinical Trials (2)

Expanded Access to Tipifarnib

Available
Expanded AccessKura Oncology, Inc.

A Phase 1/2 Open-label, Biomarker-defined Cohort Trial to Evaluate the Safety, Determine the Recommended Combination Dosing, and Assess Early Antitumor Activity of Tipifarnib and Alpelisib for the Treatment of Adult Participants Who Have HRAS-overexpressing and/or PIK3CA-mutated and/or - Amplified Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

NCT04997902·Phase 1/Phase 2·KURA
Completed

Primary endpoint: Dose-limiting toxicity (DLT)

Interventionalopen45 enrolledStarted 2021-12Completion 2025-0811 sites · United StatesKura Oncology, Inc.

Frequently asked questions

Who is developing tipifarnib?

tipifarnib is being developed by Kura Oncology, Inc..

How many clinical trials involve tipifarnib?

BioSniper tracks 2 clinical trials involving tipifarnib.