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rucaparib

Generic: rucaparib·Brand: Rubraca

rucaparib: 16 clinical trials tracked.

rucaparib evidence translation

What we can confirm

16 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about rucaparib, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 3 study sponsors
Clinical Trials (16)showing 10 most recent

Phase II Study of Rucaparib and Nivolumab in Patients With Leiomyosarcoma

NCT04624178·Phase 2
Active, not recruiting

Primary endpoint: Best Objective Response Rate

Interventionalopen20 enrolledStarted 2020-11Completion 2026-117 sites · United StatesMemorial Sloan Kettering Cancer Center

Analysis of the Clinical Experience With Rucaparib in the Rucaparib Access Program (RAP) in Spain - A GEICO Study

Completed

Primary endpoint: Number of Participants With Relevant Co-morbidities

Observational51 enrolledStarted 2020-07Completion 2021-0723 sites · SpainGrupo Español de Investigación en Cáncer de Ovario

A Phase Ib/II Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer

NCT04253262·Phase 1/Phase 2

Primary endpoint: Maximum Tolerated Dose

Interventionalopen13 targetStarted 2020-04Completion 2027-012 sites · United StatesBrown University

Pan-Tumor Study for Long-term Treatment of Cancer Patients Who Have Participated in BMS Sponsored Trials Investigating Nivolumab and Other Cancer Therapies

NCT03899155·Phase 2·BMY
Recruiting

Primary endpoint: Incidence of Adverse Events (AEs)

Interventionalopen1,500 targetStarted 2019-08Completion 2029-0850 sites · United StatesBristol-Myers Squibb

An Open Label, Non-Randomized Multisite Phase II Trial Combining Bevacizumab, Atezolizumab and Rucaparib for the Treatment of Previously Treated Recurrent and Progressive Endometrial Carcinoma

NCT03694262·Phase 2
Completed

Primary endpoint: Treatment Related Overall Response Rate

Interventionalopen30 enrolledStarted 2019-07Completion 2026-033 sites · United StatesMedical College of Wisconsin

A Phase II, Randomized, Double-Blind Study of the Use of Rucaparib vs. Placebo Maintenance Therapy in Metastatic and Recurrent Endometrial Cancer

NCT03617679·Phase 2
Completed

Primary endpoint: Progression Free Survival (PFS)

InterventionalRandomizeddouble79 enrolledStarted 2019-03Completion 2026-021 site · United StatesUniversity of Colorado, Denver

An Open Label, Multicenter Extension Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study (IMbrella B)

NCT03768063·Phase 3·KYNB
Active, not recruiting

Primary endpoint: Number of Participants With Continued Access to Atezolizumab-Based Therapy and/or Comparator Agent(s)

Interventionalopen1,000 targetStarted 2019-02Completion 2028-0750 sites · Australia, Belgium, Brazil, Bulgaria…Hoffmann-La Roche

Mesothelioma Stratified Therapy (MiST): A Stratified Multi-arm Phase IIa Clinical Trial to Enable Accelerated Evaluation of Targeted Therapies for Relapsed Malignant Mesothelioma

NCT03654833·Phase 2
Completed

Primary endpoint: Disease Control Rate (DCR) at 12 Weeks Assessed by Modified RECIST 1.1, in Patients With Relapsed Mesothelioma.

Interventionalopen186 enrolledStarted 2019-01Completion 2024-031 site · United KingdomUniversity of Leicester

A Phase I/II Multi-site Study of Rucaparib and Pembrolizumab Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung Cancer After Initial Therapy With Carboplatin, Pemetrexed, and Pembrolizumab

NCT03559049·Phase 1/Phase 2
Terminated

Primary endpoint: Median Duration of Time From Start of Treatment to Time of Progression

Interventionalopen25 targetStarted 2018-12Completion 2025-053 sites · United StatesUniversity of Michigan Rogel Cancer Center

A Phase I Study of Rucaparib Administered Concurrently With Postoperative Radiotherapy in Patients With Triple Negative Breast Cancer With an Incomplete Pathologic Response Following Neoadjuvant Chemotherapy

NCT03542175·Phase 1
Completed

Primary endpoint: Dose Limiting Toxicities

Interventionalopen31 enrolledStarted 2018-05Completion 2025-098 sites · United StatesMemorial Sloan Kettering Cancer Center