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rintatolimod

rintatolimod: 7 clinical trials tracked.

rintatolimod evidence translation

What we can confirm

7 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about rintatolimod, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 1 study sponsors
Clinical Trial Registry Records (7)

A Phase 2 Randomized Open-Label Controlled Study to Evaluate the Efficacy and Safety of Ampligen in Combination With Standard of Care Versus SOC Alone Following First-Line Therapy in Subjects With Locally Advanced Pancreatic Adenocarcinoma

NCT05494697Registry updated 2026-08-19·Phase 2·AIM
Suspended

Primary endpoint: Progression Free Survival (PFS)

InterventionalRandomizedopen90 targetStarted 2027-08Completion 2031-033 sites · United StatesAIM ImmunoTech Inc.

A Phase 2 Efficacy Trial of Intensive Locoregional Chemoimmunotherapy, Intradermal Autologous Alpha-DC1 Vaccines, and Systemic Pembrolizumab for Advanced-Stage Ovarian Cancer

NCT07634094Registry updated 2026-06-08·Phase 2
Not yet recruiting

Primary endpoint: Dose Limiting Toxicities (DLT)

Interventionalopen28 targetStarted 2026-08Completion 2029-081 site · United StatesKalinski, Pawel, MD, PhD

A Phase II Study of Type-1 Polarized Dendritic Cell (aDC1) -Based Treatment in Combination With Tumor-Selective Chemokine Modulation (CKM: Interferon Alpha 2b, Rintatolimod and Celecoxib) in Melanoma Patients With Primary PD-1/PD-L1 Resistance

NCT04093323Registry updated 2026-02-25·Phase 2
Terminated

Primary endpoint: Objective Response Rate (ORR)

Interventionalopen1 targetStarted 2024-11Completion 2025-061 site · United StatesRoswell Park Cancer Institute

Combining Anti-PD-L1 Immune Checkpoint Inhibitor Durvalumab With TLR-3 Agonist Rintatolimod in Patients With Metastatic Pancreatic Ductal Adenocarcinoma for Therapy Efficacy

NCT05927142Registry updated 2026-09-29·Phase 1/Phase 2
Active, not recruiting

Primary endpoint: Phase Ib: Determine safety of combination therapy with durvalumab and rintatolimod

Interventionalopen43 targetStarted 2024-01Completion 2027-041 site · NetherlandsJoachim Aerts, MD PhD

Phase 1/2A Study of Rintatolimod and IFN Alpha Regimen in Cancer Patients With COVID-19

NCT04379518Registry updated 2026-01-13·Phase 1/Phase 2
Terminated

Primary endpoint: Number of Participants With Adverse Events (AEs)

Interventionalopen4 targetStarted 2020-11Completion 2023-031 site · United StatesRoswell Park Cancer Institute

Randomized Phase 2 Study: Neoadjuvant Conditioning of Prostate Cancer Tumor Microenvironment Using a Novel Chemokine-Modulating Regimen

NCT03899987Registry updated 2026-06-09·Phase 2
Active, not recruiting

Primary endpoint: Count of tumor infiltrating CD8+ lymphocytes

InterventionalRandomizedopen12 targetStarted 2019-11Completion 2027-041 site · United StatesRoswell Park Cancer Institute

Systemic Immune Checkpoint Blockade and Intraperitoneal Chemo-Immunotherapy in Recurrent Ovarian Cancer

NCT03734692Registry updated 2026-02-12·Phase 1/Phase 2
Active, not recruiting

Primary endpoint: Objective Response Rate (ORR)

Interventionalopen24 targetStarted 2019-01Completion 2027-011 site · United StatesRobert Edwards