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interferon alfa-2b

Generic: interferon alfa-2b

interferon alfa-2b: 5 clinical trials tracked.

interferon alfa-2b evidence translation

What we can confirm

5 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about interferon alfa-2b, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

Clinical Trial Registry Records (5)

A Phase II Study of Type-1 Polarized Dendritic Cell (aDC1) -Based Treatment in Combination With Tumor-Selective Chemokine Modulation (CKM: Interferon Alpha 2b, Rintatolimod and Celecoxib) in Melanoma Patients With Primary PD-1/PD-L1 Resistance

NCT04093323Registry updated 2026-02-25·Phase 2
Terminated

Primary endpoint: Objective Response Rate (ORR)

Interventionalopen1 targetStarted 2024-11Completion 2025-061 site · United StatesRoswell Park Cancer Institute

Phase 1/2A Study of Rintatolimod and IFN Alpha Regimen in Cancer Patients With COVID-19

NCT04379518Registry updated 2026-01-13·Phase 1/Phase 2
Terminated

Primary endpoint: Number of Participants With Adverse Events (AEs)

Interventionalopen4 targetStarted 2020-11Completion 2023-031 site · United StatesRoswell Park Cancer Institute

Randomized Phase 2 Study: Neoadjuvant Conditioning of Prostate Cancer Tumor Microenvironment Using a Novel Chemokine-Modulating Regimen

NCT03899987Registry updated 2026-06-09·Phase 2
Active, not recruiting

Primary endpoint: Count of tumor infiltrating CD8+ lymphocytes

InterventionalRandomizedopen12 targetStarted 2019-11Completion 2027-041 site · United StatesRoswell Park Cancer Institute

A Phase III Randomized Study of Adjuvant Ipilimumab Anti-CTLA4 Therapy Versus High-Dose Interferon a-2b for Resected High-Risk Melanoma

NCT01274338Registry updated 2026-02-18·Phase 3
Active, not recruiting

Primary endpoint: Recurrence-free Survival (RFS; Arm B [HDI] vs. Arm C [LIP])

InterventionalRandomizedopen1,673 targetStarted 2011-05Completion 2026-0350 sites · United StatesNational Cancer Institute (NCI)

Phase III Randomized Study of Four Weeks of High Dose Interferon Alfa-2b in Stage T2bN0, T3a-bN0, T4a-bN0, and T1-4, N1a,2a (Microscopic) Melanoma

NCT00003641Registry updated 2026-09-29·Phase 3
Completed

Primary endpoint: 5-year Relapse-free Survival Rate

InterventionalRandomizedopen1,150 enrolledStarted 1999-03Completion 2026-05533 sites · Australia, Canada, South Africa, United StatesECOG-ACRIN Cancer Research Group