Skip to main content

pioglitazone

Generic: PIOGLITAZONE HYDROCHLORIDE·Brand: ACTOS, Actoplus Met, Actos, Duetact, Oseni, PIOGLITAZONE HYDROCHLORIDE

pioglitazone: 5 clinical trials tracked.

pioglitazone evidence translation

What we can confirm

5 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about pioglitazone, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 2 study sponsors
Clinical Trial Registry Records (5)

An Open-label, Fixed-sequence, Two-part Study to Assess the Effect of AZD5004 on the Pharmacokinetics of Mitiglinide and Pioglitazone in Healthy Participants

NCT07444424Registry updated 2026-07-13·Phase 1·AZN
Completed

Primary endpoint: Area under concentration-time curve from time 0 to infinity (AUCinf)

Interventionalopen32 enrolledStarted 2026-03Completion 2026-071 site · JapanAstraZeneca

Effects of Pioglitazone on Exogenous Carbohydrate Oxidation During Steady-State Exercise at High Altitude

NCT06164665Registry updated 2026-03-19·Phase 4
Completed

Primary endpoint: Rate of Exogenous Glucose Oxidation

InterventionalRandomizeddouble9 enrolledStarted 2023-03Completion 2023-071 site · United StatesUnited States Army Research Institute of Environmental Medicine

A Phase II Study on Trabectedin in Combination With PPARg Agonist Pioglitazone in Patients With Round Cell Myxoid Liposarcomas or Dedifferentiated G1 and G2 Liposarcomas With Stable Disease After a Monotherapy With Trabectedin. (TRABEPIO)

NCT04794127Registry updated 2026-02-18·Phase 2
Completed

Primary endpoint: Objective response (OR) in patients with myxoid liposarcomas according to RECIST criteria or CHOI criteria

Interventionalopen10 enrolledStarted 2022-02Completion 2024-091 site · ItalyMario Negri Institute for Pharmacological Research

Preservation of Beta Cell Function in Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

NCT02969798Registry updated 2026-09-22·N/A
Recruiting

Primary endpoint: Beta cell function

InterventionalRandomizedopen700 targetStarted 2014-01Completion 2027-071 site · United StatesThe University of Texas Health Science Center at San Antonio

A Phase 2 Multicenter, Randomized, Double-Blind, Placebo- and Active Comparator-Controlled Study to Evaluate the Safety and Efficacy of MBX-102/JNJ-39659100 in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy

NCT00814372Registry updated 2026-09-18·Phase 2·GILD
Terminated

Primary endpoint: Change in HbA1c from baseline and compared to placebo

InterventionalRandomizedtriple242 enrolledStarted 2008-12Completion 2010-0226 sites · India, United StatesGilead Sciences