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dapagliflozin

Generic: DAPAGLIFLOZIN·Brand: DAPAGLIFLOZIN, FARXIGA, Farxiga, Qtern, Xigduo

dapagliflozin: 12 clinical trials tracked.

dapagliflozin evidence translation

What we can confirm

12 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about dapagliflozin, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence5 indications · 3 study sponsors
Clinical Trials (12)showing 10 most recent

A Phase III, Randomised, Double-blind, Study to Evaluate the Effect of Balcinrenone/Dapagliflozin Compared With Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Chronic Kidney Disease (Stage 3b and 4)

NCT07624305·Phase 3·AZN
Not yet recruiting

Primary endpoint: Time from randomization to first occurrence of cardiovascular death, death from kidney failure, kidney failure, sustained 50% or greater decline in eGFR, and heart failure event

InterventionalRandomizedquadruple2,800 targetStarted 2026-09Completion 2030-0745 sites · Argentina, Canada, Germany, Japan…AstraZeneca

Dapagliflozin for Long COVID Syndrome

NCT06907251·Phase 3·GHRS
Not yet recruiting

Primary endpoint: 6 month change in EQ-5D derived utility score.

InterventionalRandomizedquadruple192 targetStarted 2026-09Completion 2029-061 site · CanadaOttawa Heart Institute Research Corporation

A Randomized, Double-blind, Parallel-group Phase III Study to Evaluate the Efficacy, Safety, and Tolerability of Elecoglipron and Dapagliflozin in Combination, Compared With Elecoglipron Alone and Dapagliflozin Alone, in Adults With Type 2 Diabetes Mellitus (Eluminate-5)

NCT07662109·Phase 3·AZN
Recruiting

Primary endpoint: Change from baseline in Hemoglobin A1c (HbA1c)

InterventionalRandomizedquadruple2,000 targetStarted 2026-07Completion 2028-0750 sites · Argentina, Brazil, United StatesAstraZeneca

A Randomized, Double-blind, Parallel-group Phase III Study to Evaluate the Efficacy, Safety, and Tolerability of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus (Eluminate-1)

NCT07662044·Phase 3·AZN
Recruiting

Primary endpoint: Change from baseline in Hemoglobin A1c (HbA1c)

InterventionalRandomizedquadruple800 targetStarted 2026-07Completion 2028-0750 sites · Argentina, China, United StatesAstraZeneca

Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Adolescents With Persistent Albuminuria: A Randomized Controlled Clinical Trial

NCT07405216·Phase 4·TVTX
Not yet recruiting

Primary endpoint: Albuminuria

InterventionalRandomizedtriple200 targetStarted 2026-03Completion 2026-10Centenario Hospital Miguel Hidalgo

An Open-Label Safety and Tolerability Pilot Study of Dapagliflozin in Stage IA Lung Adenocarcinoma

NCT07235280·Early Phase 1·TVTX
Recruiting

Primary endpoint: Incidence of adverse events

Interventionalopen48 targetStarted 2025-12Completion 2029-061 site · United StatesJonsson Comprehensive Cancer Center

A Multicentre, Randomised, Double-blind, Active-Controlled, 2-arm Parallel-group Treatment, Phase II Study to Evaluate the Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin Alone in Adult Participants With Chronic Kidney Disease and High Proteinuria

NCT06942910·Phase 2·AZN
Recruiting

Primary endpoint: Change in log-transformed Urinary Albumin to Creatinine Ratio (UACR) from baseline

InterventionalRandomizedtriple224 targetStarted 2025-05Completion 2026-0715 sites · RussiaAstraZeneca

A Phase III, Randomised, Multicentre, Double-blind Study to Evaluate the Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin Alone in Participants With Chronic Kidney Disease and High Proteinuria

NCT06087835·Phase 3·AZN
Active, not recruiting

Primary endpoint: Change in eGFR from baseline

InterventionalRandomizedquadruple1,835 targetStarted 2023-11Completion 2027-0250 sites · United StatesAstraZeneca

Assessment of Dapagliflozin on Vascular Health in Patients With Type 2 Diabetes

NCT05139914·Phase 4·TVTX
Terminated

Primary endpoint: Mean Systolic Blood Pressure

InterventionalRandomizeddouble4 targetStarted 2022-05Completion 2025-021 site · United StatesBoston University

A Multicenter, Randomized, Double-Blind, Parallel Group, Placebo-Controlled Trial to Evaluate the Effect of In-Hospital Initiation of Dapagliflozin on Clinical Outcomes in Patients Who Have Been Stabilized During Hospitalization for Acute Heart Failure DAPAgliflozin and Effect on Cardiovascular Events in ACuTe Heart Failure -Thrombolysis in Myocardial Infarction 68 (DAPA ACT HF-TIMI 68)

NCT04363697·Phase 4
Completed

Primary endpoint: Participants With the Composite Outcome of Cardiovascular Death or Worsening Heart Failure

InterventionalRandomizedquadruple2,401 enrolledStarted 2020-09Completion 2025-061 site · United StatesThe TIMI Study Group