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isoniazid

Generic: ISONIAZID·Brand: DOW-ISONIAZID, HYZYD, INH, ISONIAZID, LANIAZID, NYDRAZID, RIMIFON, STANOZIDE

isoniazid: 6 clinical trials tracked.

isoniazid evidence translation

What we can confirm

6 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about isoniazid, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 1 study sponsors
Clinical Trials (6)

Shortened Regimen for Drug-susceptible TB in Children

NCT06253715·Phase 3
Recruiting

Primary endpoint: TB disease-free survival at 48-weeks

InterventionalRandomizedopen860 targetStarted 2025-01Completion 2027-099 sites · India, Indonesia, Mozambique, South Africa…Johns Hopkins University

Co-SAM: An Adaptive Multi-arm Trial to Improve Clinical Outcomes Among Children Recovering From Complicated Severe Acute Malnutrition

NCT05994742·Phase 3
Completed

Primary endpoint: Death or first hospitalisation or failed nutritional recovery within 24 weeks post-randomisation

InterventionalRandomizedopen674 enrolledStarted 2024-07Completion 2026-079 sites · Kenya, Zambia, ZimbabweQueen Mary University of London

A Phase IIc, Open-Label, Randomized Controlled Trial of Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible Tuberculosis (PRESCIENT)

NCT05556746·Phase 2·CRNX
Active, not recruiting

Primary endpoint: Time to stable liquid culture conversion

InterventionalRandomizedopen156 targetStarted 2023-11Completion 2027-012 sites · Haiti, South AfricaBrigham and Women's Hospital

A Multicenter, Phase 2b/c, Open-label, Randomized, Dose-finding Trial to Evaluate the Safety and Efficacy of a 4 Month Regimen of OPC-167832 in Combination With Delamanid and Bedaquiline in Subjects With Drug-susceptible Pulmonary Tuberculosis in Comparison With Standard Treatment

NCT05221502·Phase 2
Completed

Primary endpoint: Number of Participants With Treatment-Emergent Adverse Events (TEAEs), Serious TEAEs, Severe TEAEs, TEAEs Related to Study Drug, TEAEs Leading to Study Discontinuation, TEAEs Leading to Death, and All Grade TEAEs Based on DAIDS Criteria

InterventionalRandomizedopen122 enrolledStarted 2022-04Completion 2024-056 sites · South AfricaOtsuka Pharmaceutical Development & Commercialization, Inc.

Phase I/II Dose Finding and Safety Study of Rifapentine and Isoniazid in HIV-Infected and HIV-Uninfected Children With Latent Tuberculosis Infection

NCT03730181·Phase 1/Phase 2
Completed

Primary endpoint: Rifapentine Pharmacokinetic Exposure (AUC) Following Weekly 3HP Administration

Interventionalopen69 enrolledStarted 2019-11Completion 2025-051 site · South AfricaCenters for Disease Control and Prevention

A Randomized, Placebo-Controlled Study of Limited vs. Continuous Isoniazid Tuberculosis Preventive Therapy in HIV-infected Persons in Botswana

NCT00164281·Phase 4
Completed

Primary endpoint: Number of Participants With Incident Tuberculosis

InterventionalRandomizedtriple1,995 enrolledStarted 2004-11Completion 2011-051 site · BotswanaCenters for Disease Control and Prevention