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clofazimine

Generic: CLOFAZIMINE·Brand: LAMPRENE

clofazimine: 5 clinical trials tracked.

clofazimine evidence translation

What we can confirm

5 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about clofazimine, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 1 study sponsors
Clinical Trials (5)

A Multi-centre, Randomised Trial Comparing a Novel Combination Treatment (Arm D - Intravenous Sulbactam-durlobactam in Combination With Intravenous Ceftriaxone, Oral Amoxicillin, Oral Azithromycin and Oral Clofazimine) Versus Standard of Care Treatments for the Intensive Phase of Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trial

NCT07485010·Phase 2
Not yet recruiting

Primary endpoint: The primary outcome of the Intervention Program is microbiological clearance of Mycobacterium abscessus (MABS) with good tolerance of the interventions.

InterventionalRandomizedopen300 targetStarted 2027-04Completion 2031-07The University of Queensland

A Phase IIc, Open-Label, Randomized Controlled Trial of Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible Tuberculosis (PRESCIENT)

NCT05556746·Phase 2·CRNX
Active, not recruiting

Primary endpoint: Time to stable liquid culture conversion

InterventionalRandomizedopen156 targetStarted 2023-11Completion 2027-012 sites · Haiti, South AfricaBrigham and Women's Hospital

A Phase II, Prospective, Randomized, Multicenter Trial to Evaluate the Efficacy and Safety/Tolerability of Two Linezolid Dosing Strategies in Combination With a Short Course Regimen for the Treatment of Drug-Resistant Pulmonary Tuberculosis

NCT05007821·Phase 2
Completed

Primary endpoint: Time to 26 Weeks Stable Culture Conversion in Liquid Media

InterventionalRandomizedopen138 enrolledStarted 2022-09Completion 2026-0113 sites · Botswana, Brazil, Haiti, Peru…National Institute of Allergy and Infectious Diseases (NIAID)

Prospective, Randomized, Partially Blinded, Phase 2 Study of the Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine for Treatment of Patients With MDR-TB

NCT03828201·Phase 2
Active, not recruiting

Primary endpoint: Treatment Efficacy - Frequency of "successful treatment" outcomes

InterventionalRandomizedopen271 enrolledStarted 2022-06Completion 2027-052 sites · Philippines, VietnamBoston University

Natural History, Genetics, Phenotype, and Treatment of Mycobacterial Infections

Recruiting

Primary endpoint: Collect patients with nontuberculous mycobacterial infections in order to identify known and novel immune defects, characterize the natural history of these infections in the setting of the best possible standard therapy, and explore the connect...

Observational1,000 targetStarted 2001-011 site · United StatesNational Institute of Allergy and Infectious Diseases (NIAID)