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insulin, regular, human

Generic: insulin, regular, human·Brand: Afrezza, Humulin, Humulin R, Myxredlin, Novolin, Novolin R

insulin, regular, human: developed by 2 companies · 7 clinical trials tracked · 1 FDA decision.

insulin, regular, human evidence translation

What we can confirm

1 FDA record · 7 tracked trials

What it means

More than one developer is source-backed. Until you choose one, AI stays drug-only and does not guess ownership.

What to watch

Watch active trials and any change in FDA or trial status.
BioSniper AIPage evidence connected

Prepared research question

What is verified about insulin, regular, human, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence5 indications · 1 study sponsors

Related indications

Diabetes care (insulin)Diabetes Mellitus, Type 1; Type 1 DiabetesDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Insulin Resistance
Development Pipeline (2)
CompanyPhase
Amphastar Pharmaceuticals, Inc. (AMPH)
Diabetes care (insulin)
Phase 2/Phase 3
MANNKIND CORP (MNKD)
Diabetes Mellitus, Type 1; Type 1 Diabetes
Phase 3
Clinical Trials (7)

Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance

NCT07494084·Phase 4
Not yet recruiting

Primary endpoint: Insulin resistance-Minimal Model (Si)

InterventionalRandomizeddouble48 targetStarted 2026-07Completion 2029-071 site · United StatesWashington State University

A Randomized, Double-blind, Placebo-controlled, Multi-center Phase 2b Study With a Blinded Extension and an Optional Open-label Extension-Assessing the Safety and Efficacy of Frexalimab, a CD40L-antagonist Monoclonal Antibody, for the Preservation of Pancreatic β-cell Function in Adults, Adolescents and Children With Newly Diagnosed Type 1 Diabetes on Insulin Therapy

NCT06111586·Phase 2·SNY
Active, not recruiting

Primary endpoint: Change in mean 2h mixed meal tolerance test (MMTT) stimulated C-peptide concentration, calculated from AUC from baseline to W52 for Part B (12-21 y.o.)

InterventionalRandomizedtriple197 targetStarted 2023-12Completion 2030-1050 sites · Austria, Belgium, Canada, Czechia…Sanofi

ABC [Afrezza With Basal Combination]: A Phase 4 Study of Mealtime Control With Afrezza in Adult Subjects With Type 1 Diabetes Mellitus in Combination With an Automated Insulin Pump or Insulin Degludec

NCT05243628·Phase 4·MNKD
Completed

Primary endpoint: Change in HbA1c

InterventionalRandomizedopen33 enrolledStarted 2022-03Completion 2022-102 sites · United StatesMannkind Corporation

INHALE-1: A 26-week Primary Treatment Phase, With 26-week Extension, Open-label, Randomized Clinical Trial Evaluating the Efficacy and Safety of Afrezza® Versus Rapid-acting Insulin Analog Injections, Both in Combination With a Basal Insulin, in Pediatric Subjects With Type 1 or Type 2 Diabetes Mellitus

NCT04974528·Phase 3·MNKD
Completed

Primary endpoint: Change in HbA1c

InterventionalRandomizedopen319 enrolledStarted 2021-09Completion 2025-0439 sites · United StatesMannkind Corporation

A Single-Site, Investigator-Initiated Study to Evaluate Time in Range in Subjects With Type 2 Diabetes Mellitus Using Mealtime Inhaled Insulin (Afrezza®) Plus Basal Insulin Compared to Multiple Daily Injections

NCT04125082·Phase 4
Unknown

Primary endpoint: Time In Range

Interventionalopen29 targetStarted 2019-02Completion 2020-031 site · United StatesDiabetes and Glandular Disease Clinic

Initiating Mealtime Ultra-Rapid Acting Insulin (Afrezza) in Uncontrolled Type 2 Diabetes Patients

NCT03324776·Phase 3
Completed

Primary endpoint: Change in Percentage of HbA1c From Baseline to 3 Months

Interventionalopen20 enrolledStarted 2017-10Completion 2020-061 site · United StatesModel Clinical Research LLC

A Prospective, Multicenter, Randomized, Open-label Study of 12 Week Duration to Evaluate the Effect of VILDagliptin Added to Insulin on Glycaemic Control in haemoDIALyzed Patients With Type 2 Diabetes: Probe Analysis of CGM

NCT02176681·Phase 4
Completed

Primary endpoint: Mean glucose value of CGM [M] to be averaged from day 2 and day 3 of CGM

InterventionalRandomizedopen70 enrolledStarted 2014-06Completion 2017-1013 sites · FranceUniversity Hospital, Strasbourg, France
FDA Decisions1 records
Approval1 INDICATIONS AND USAGE AFREZZA ® is indicated to improve glycemic control in adult and pediatric patients 6 years of age and older with diabetes mellitus. AFREZZA ® is a rapid acting inhaled human insulin indicated to improve glycemic control in adult and pediatric patients 6 years of age and older with diabetes mellitus. ( 1 ) Limitations of Use : Not recommended for the treatment of diabetic ketoacidosis (DKA) ( 1 ) Not recommended in patients who smoke or who have recently stopped smoking ( (MNKD)FDA ↗
BLA022472Type 5 - New Formulation or New ManufacturerStandardInhalationPowder

Frequently asked questions

Who is developing insulin, regular, human?

insulin, regular, human is being developed by Amphastar Pharmaceuticals, Inc., MANNKIND CORP.

How many clinical trials involve insulin, regular, human?

BioSniper tracks 7 clinical trials involving insulin, regular, human.

What is insulin, regular, human's latest FDA decision?

The most recent tracked FDA decision for insulin, regular, human is Approval for 1 INDICATIONS AND USAGE AFREZZA ® is indicated to improve glycemic control in adult and pediatric patients 6 years of age and older with diabetes mellitus. AFREZZA ® is a rapid acting inhaled human insulin indicated to improve glycemic control in adult and pediatric patients 6 years of age and older with diabetes mellitus. ( 1 ) Limitations of Use : Not recommended for the treatment of diabetic ketoacidosis (DKA) ( 1 ) Not recommended in patients who smoke or who have recently stopped smoking ( , dated June 27, 2014.