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insulin degludec

Generic: insulin degludec·Brand: Tresiba, Xultophy

insulin degludec: 14 clinical trials tracked.

insulin degludec evidence translation

What we can confirm

14 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about insulin degludec, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 3 study sponsors
Clinical Trials (14)showing 10 most recent

A Phase I Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Subcutaneous Administration of UBT38006 Injection in Healthy Adult Male Subjects

NCT07630233·Phase 1
Not yet recruiting

Primary endpoint: incidence of adverse events (AEs), adverse drug reactions (ADRs), serious adverse events (SAEs), etc,..

InterventionalRandomizedquadruple53 targetStarted 2026-06Completion 2026-101 site · ChinaThe United Bio-Technology (Hengqin) Co., Ltd.

A Study Investigating Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of NNC0363-1063 in Healthy Participants and Participants With Type 1 Diabetes

NCT06685185·Phase 1·NVO
Completed

Primary endpoint: Part 1 SAD: Number of adverse events

InterventionalRandomizedquadruple117 enrolledStarted 2024-11Completion 2026-031 site · GermanyNovo Nordisk A/S

Pharmacodynamic Properties of Insulin Icodec During Exercise and Prolonged Fasting in Participants With Type 2 Diabetes

NCT06288412·Phase 1·NVO
Completed

Primary endpoint: Time below range, glucose less than (<) 3.0 millimoles per liter (mmol/L) (54 milligrams per deciliter [mg/dL]) within 24 hours after start of exercise (TBR3.0mmol/L,exe)

Interventionalopen30 enrolledStarted 2024-02Completion 2025-041 site · AustriaNovo Nordisk A/S

A Multi-centre, Prospective, Non-interventional, Single-arm Study Investigating Glycaemic Control Associated With the Use of Dose Check App and Insulin Degludec in Patients With Type 2 Diabetes Mellitus in Saudi Arabia Under Real-world Setting

Completed

Primary endpoint: Change in glycated haemoglobin (HbA1c)

Observational179 enrolledStarted 2023-11Completion 2025-0314 sites · Saudi ArabiaNovo Nordisk A/S

A Multi-center, Randomized, Open, Phase III Study of Insulin Degludec/Insulin Aspart Biosimilar (22011) Compared Efficacy and Safety With Insulin Degludec/Insulin Aspart(Ryzodeg) in Chinese Subjects With Type 2 Diabetes

NCT05802862·Phase 3
Completed

Primary endpoint: Change From Baseline in Hemoglobin A1c (HbA1c)

InterventionalRandomizedopen414 enrolledStarted 2023-07Completion 2024-081 site · ChinaSunshine Lake Pharma Co., Ltd.

A 24-Week, Multicenter, Randomized, Open-Label, Parallel-Group Trial Comparing the Efficacy and Safety of Insulin Glargine 300 U/mL (Gla-300) and Insulin Degludec 100 U/mL (IDeg-100) in Insulin-Naïve People With Type 2 Diabetes Mellitus and Renal Impairment: TRENT Trial

NCT05552859·Phase 4·SNY
Terminated

Primary endpoint: Difference in the Mean Change From Baseline to Week 24 in HbA1c Level (Gla-300 vs IDeg-100)

InterventionalRandomizedopen62 targetStarted 2022-12Completion 2023-0850 sites · Czechia, Hungary, Poland, United StatesSanofi

ABC [Afrezza With Basal Combination]: A Phase 4 Study of Mealtime Control With Afrezza in Adult Subjects With Type 1 Diabetes Mellitus in Combination With an Automated Insulin Pump or Insulin Degludec

NCT05243628·Phase 4·MNKD
Completed

Primary endpoint: Change in HbA1c

InterventionalRandomizedopen33 enrolledStarted 2022-03Completion 2022-102 sites · United StatesMannkind Corporation

A Multi-centre Prospective Non-interventional Clinical Investigation Studying the Glycaemic Control in Patients With Type 1 Diabetes When Introducing a NovoPen® 6 for Treatment With Tresiba® (Insulin Degludec) & Fiasp® (Fast-acting Insulin Aspart) in a Real-world Setting

Completed

Primary endpoint: Change in time in range (3.9-10 mmol/L)

Observational411 enrolledStarted 2021-10Completion 2024-0926 sites · Belgium, Denmark, France, SwedenNovo Nordisk A/S

A Multi-centre, Prospective, Open-label, Single-arm, Non-interventional, Regulatory Post Marketing Surveillance (rPMS) Study of Xultophy® (Insulin Degludec / Liraglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea

Completed

Primary endpoint: Incidence of Adverse Events (AEs) by preferred term

Observational750 enrolledStarted 2021-06Completion 2024-1232 sites · South KoreaNovo Nordisk A/S

Efficacy and Safety of Once Weekly Insulin Icodec Compared to Once Daily Insulin Degludec 100 Units/mL, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes. A 26-week, Randomised, Multicentre, Open-label, Active-controlled, Parallel Group, Two Armed, Treat-to-target Trial Investigating the Effect on Glycaemic Control and Safety of Treatment With Once Weekly Insulin Icodec Compared to Once Daily Insulin Degludec, Both in Combination With Insulin Aspart in Adults With Type 1 Diabetes, With a 26-week Extension Investigating Long Term Safety

NCT04848480·Phase 3·NVO
Completed

Primary endpoint: Change in Glycosylated Haemoglobin (HbA1c) at Week 26

InterventionalRandomizedopen582 enrolledStarted 2021-04Completion 2022-1250 sites · Austria, Canada, United StatesNovo Nordisk A/S