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immunoglobulin G

Generic: immunoglobulin G·Brand: Bivigam, Cuvitru, Flebogamma, GamaSTAN, Gammagard, Gammagard ERC, Gammaked, Gammaplex, Gamunex, Hizentra, Octagam, Privigen, Xembify

immunoglobulin G: developed by 1 company · 8 clinical trials tracked.

immunoglobulin G evidence translation

What we can confirm

What it means

Source-backed records connect immunoglobulin G to ADMA; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could immunoglobulin G → ADMA affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence4 indications · 4 study sponsors
Development Pipeline (1)
CompanyPhase
ADMA BIOLOGICS, INC. (ADMA)
Treatment of Primary Humoral Immunodeficiency (PI) / Primary…
Approved
Clinical Trials (8)

The Efficacy of Intravenous Immunoglobulin for the Treatment of Bronchopulmonary Dysplasia

NCT06925360·Phase 2·HWH
Recruiting

Primary endpoint: Diagnosis of bronchopulmonary dysplasia and severity of the condition at 36 weeks of PMA

Interventionalopen20 targetStarted 2025-04Completion 2027-121 site · ChinaInternational Peace Maternity and Child Health Hospital

Post-marketing Database Survey: A Cohort Study to Evaluate the Safety of Cuvitru in Patients With Primary Immunodeficiency Using the PIDJ2 (Primary Immunodeficiency Database in Japan) Registry

Recruiting

Primary endpoint: Number of Participants Who Experience Anaphylactic Reaction as an Adverse Event (AE)

Observational100 targetStarted 2025-02Completion 2030-031 site · JapanTakeda

Multicenter, Open-Label, Randomized Study of Nipocalimab or IVIG in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

NCT06533098·Phase 3
Recruiting

Primary endpoint: Fetus/Neonate with Outcome of Death or Adjudicated Severe Bleeding or Platelet Count Less Than (<) 30*10^9/L

InterventionalRandomizedopen50 targetStarted 2025-02Completion 2029-1226 sites · Austria, Germany, Netherlands, Poland…Janssen Research & Development, LLC

Phase 2, Randomized, Patient- and Rater-blinded Single-site Trial Evaluating Safety and Efficacy of Efgartigimod in Patients With Guillain-Barré Syndrome.

NCT05701189·Phase 2
Withdrawn

Primary endpoint: Guillain-Barre Syndrome Disability Scale (GBS-DS)

InterventionalRandomizeddouble0 targetStarted 2024-09Completion 2026-021 site · United StatesChafic Karam

An Open-label, Multicenter, Phase 4 Study to Assess the Effects of a Prophylactic Immune Tolerizing Regimen in MPS II Treatment-Naïve Patients Planned to Receive ELAPRASE Who Are at Risk of Developing Persistent Neutralizing Antibodies

NCT05494593·Phase 4·TAK
Withdrawn

Primary endpoint: Rate of Anti-Idursulfase Antibodies Formation, Including Anti-Idursulfase Antibodies That Have Enzyme Neutralizing Activity

Interventionalopen0 targetStarted 2023-02Completion 2025-088 sites · United StatesTakeda

A Multi-cohort, Randomized, Phase 2, Open-label Study to Assess the Preliminary Efficacy, Safety, and Pharmacokinetics of BIVV020 for Prevention and Treatment of Antibody-mediated Rejection in Adult Kidney Transplant Recipients.

NCT05156710·Phase 2·SNY
Active, not recruiting

Primary endpoint: Cohort A: Treatment failure rate

InterventionalRandomizedopen48 enrolledStarted 2022-06Completion 2026-1027 sites · Canada, France, Germany, Italy…Sanofi

A 4-part Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of M254 in Healthy Volunteers and in Patients With Immune Thrombocytopenic Purpura

NCT03866577·Phase 1/Phase 2·MNTA
Terminated

Primary endpoint: Parts A, B, and C: Number of Participants With Treatment-emergent Adverse Events (TEAEs) by Severity

InterventionalRandomizedopen50 targetStarted 2018-12Completion 2021-0628 sites · Belgium, Hungary, Italy, Netherlands…Momenta Pharmaceuticals, Inc.

Phase 1-2 Trial of Gamunex (Intravenous Gammaglobulin) for Sickle Cell Acute Pain

NCT01757418·Phase 1/Phase 2
Completed

Primary endpoint: Length of vaso-occlusive crisis (VOC)

InterventionalRandomizedquadruple300 enrolledStarted 2008-11Completion 2024-121 site · United StatesAlbert Einstein College of Medicine

Frequently asked questions

Who is developing immunoglobulin G?

immunoglobulin G is being developed by ADMA BIOLOGICS, INC..

How many clinical trials involve immunoglobulin G?

BioSniper tracks 8 clinical trials involving immunoglobulin G.