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chs-114

Generic: anti-CCR8 antibody·Code: SRF114

chs-114: developed by 2 companies · 2 clinical trials tracked.

chs-114 evidence translation

What we can confirm

2 tracked trials

What it means

More than one developer is source-backed. Until you choose one, AI stays drug-only and does not guess ownership.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about chs-114, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 0 study sponsors

Related indications

Metastatic Solid Tumor; Advanced Solid TumorCancer immunotherapyHead and Neck Squamous Cell Carcinoma

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (2)
CompanyPhase
Coherus Oncology, Inc. (CHRS)
Metastatic Solid Tumor; Advanced Solid Tumor
Phase 1
VACCINEX, INC. (VCNX)
Cancer immunotherapy
Phase 1
Clinical Trials (2)

A Phase 1B, Multicenter, Open-Label Study of the Safety and Efficacy of CHS-114 in Combination With Toripalimab With or Without Other Treatments in Participants With Advanced or Metastatic Solid Tumors (TREGCHECK 102)

NCT06657144·Phase 1·CHRS
Recruiting

Primary endpoint: Number of Participants With Treatment-emergent Adverse Events (TEAEs)

InterventionalRandomizedopen154 targetStarted 2025-04Completion 2028-0130 sites · Taiwan, United StatesCoherus Oncology, Inc.

A Phase 1 Study of CHS-114 in Participants With Advanced Solid Tumors

NCT05635643·Phase 1·CHRS
Active, not recruiting

Primary endpoint: [Arms 1a, 1b, and 2] Rate of Dose Limiting Toxicity (DLT)

InterventionalRandomizedopen87 targetStarted 2022-12Completion 2027-0112 sites · United StatesCoherus Oncology, Inc.

Frequently asked questions

Who is developing chs-114?

chs-114 is being developed by Coherus Oncology, Inc., VACCINEX, INC..

How many clinical trials involve chs-114?

BioSniper tracks 2 clinical trials involving chs-114.