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bosutinib

Generic: bosutinib·Brand: Bosulif

bosutinib: 7 clinical trials tracked.

bosutinib evidence translation

What we can confirm

7 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about bosutinib, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 3 study sponsors
Clinical Trials (7)

This is a Global, Multi-center, Open-label Randomized and Registrational Phase 3 Study of Olverembatinib (HQP1351) in Patients With Chronic Phase Chronic Myeloid Leukemia

NCT06423911·Phase 3·AAPG
Recruiting

Primary endpoint: MMR rate Part A

InterventionalRandomizedopen285 targetStarted 2024-02Completion 2026-021 site · United StatesAscentage Pharma Group Inc.

An Open Label, Multi-center Asciminib Roll-over Study to Assess Long-term Safety in Patients Who Have Completed a Novartis Sponsored Asciminib Study and Are Judged by the Investigator to Benefit From Continued Treatment

NCT04877522·Phase 4·NVS
Recruiting

Primary endpoint: Number of participants with adverse events (AEs) and serious adverse events (SAEs)

Interventionalopen347 targetStarted 2022-08Completion 2030-0850 sites · Argentina, Austria, Brazil, Bulgaria…Novartis Pharmaceuticals

A Phase III, Multi-center, Open-label, Randomized Study of Oral Asciminib Versus Investigator Selected TKI in Patients With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase

NCT04971226·Phase 3·NVS
Active, not recruiting

Primary endpoint: Percentage of Participants With Major Molecular Response (MMR) at Week 48 - Ascimimib vs. Investigator Selected TKI

InterventionalRandomizedopen405 enrolledStarted 2021-10Completion 2031-0150 sites · Australia, Austria, Belgium, Bulgaria…Novartis Pharmaceuticals

A Retrospective Observational Research Study to Describe the Real World Use of Bosutinib in a Single Centre in Scotland

Completed

Primary endpoint: Cumulative response rate in partial and complete haematological response (PHR/CHR)

Observational17 enrolledStarted 2019-05Completion 2019-111 site · United KingdomPfizer

A Randomized Phase II Study of Ruxolitinib (NSC-752295) in Combination With BCR-ABL Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia (CML) Patients With Molecular Evidence of Disease

NCT03654768·Phase 2
Active, not recruiting

Primary endpoint: Rate of Molecular Response 4.5 (MR4.5)

InterventionalRandomizedopen81 targetStarted 2018-10Completion 2028-0750 sites · United StatesSWOG Cancer Research Network

Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR): A Phase II Basket Trial

NCT03297606·Phase 2
Recruiting

Primary endpoint: Objective response rate defined as the number of patients with complete response or partial response

Interventionalopen720 targetStarted 2018-03Completion 2027-0110 sites · CanadaCanadian Cancer Trials Group

A Phase 3, Multi-center, Open-label, Randomized Study of Oral ABL001 Versus Bosutinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase (CML-CP), Previously Treated With 2 or More Tyrosine Kinase Inhibitors

NCT03106779·Phase 3·NVS
Completed

Primary endpoint: Major Molecular Response (MMR) Rate at 24 Weeks

InterventionalRandomizedopen233 enrolledStarted 2017-10Completion 2024-1250 sites · Argentina, Australia, Brazil, Bulgaria…Novartis Pharmaceuticals