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bet inhibitor incb057643

Generic: BET Inhibitor INCB057643

bet inhibitor incb057643: 4 clinical trials tracked.

bet inhibitor incb057643 evidence translation

What we can confirm

4 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about bet inhibitor incb057643, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence3 indications · 1 study sponsors
Clinical Trial Registry Records (4)

Relative Bioavailability of New Formulations of INCB057643 Tablets Administered Orally in Healthy Participants

NCT06941077Registry updated 2025-06-11·Phase 1·INCY
Completed

Primary endpoint: Pharmacokinetics Parameter (PK): Cmax of INCB057643

InterventionalRandomizedopen48 enrolledStarted 2025-05Completion 2025-061 site · United StatesIncyte Corporation

A Phase 1, Open-Label, Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms

NCT04279847Registry updated 2026-04-01·Phase 1·INCY
Active, not recruiting

Primary endpoint: Number of treatment-emergent adverse events

Interventionalopen140 targetStarted 2021-02Completion 2027-0448 sites · Canada, China, Finland, Italy…Incyte Corporation

A Phase 1/2 Study Exploring the Safety, Tolerability, Effect on the Tumor Microenvironment, and Efficacy of Azacitidine in Combination With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors and Previously Treated Stage IIIB or Stage IV Non-Small Cell Lung Cancer and Stage IV Microsatellite-Stable Colorectal Cancer (ECHO-206)

NCT02959437Registry updated 2025-10-21·Phase 1/Phase 2·INCY
Terminated

Primary endpoint: Part 1 and 2 : Number of Participants With Treatment Emergent Adverse Events

Interventionalopen70 targetStarted 2017-02Completion 2020-0312 sites · Spain, United Kingdom, United StatesIncyte Corporation

A Phase 1/2, Open-Label, Dose-Escalation/Dose-Expansion, Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

NCT02711137Registry updated 2025-10-21·Phase 1/Phase 2·INCY
Terminated

Primary endpoint: Number of Participants With Treatment Emergent Adverse Events (TEAE's).

Interventionalopen137 targetStarted 2016-05Completion 2019-0218 sites · Belgium, France, United StatesIncyte Corporation