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amezalpat

Generic: Amezalpat·Code: TPST-1120

amezalpat: developed by 1 company · 2 clinical trials tracked.

amezalpat evidence translation

What we can confirm

What it means

Source-backed records connect amezalpat to TPST; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could amezalpat → TPST affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 0 study sponsors

Related indications

first-line unresectable or metastatic hepatocellular carcinoma (HCC)

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
Tempest Therapeutics, Inc. (TPST)
first-line unresectable or metastatic hepatocellular carcino…
Phase 3
Clinical Trials (2)

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of TPST-1120 in Combination With Atezolizumab Plus Bevacizumab Compared With Placebo Plus Atezolizumab Plus Bevacizumab in Patients With Unresectable or Metastatic Hepatocellular Carcinoma (HCC) Not Previously Treated With Systemic Therapy

NCT06680258·Phase 3·TPST
Not yet recruiting

Primary endpoint: Overall Survival (OS)

InterventionalRandomizedquadruple740 targetStarted 2025-12Completion 2030-07Tempest Therapeutics

A Phase Ib/II, Open-Label, Multicenter, Randomized Umbrella Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

NCT04524871·Phase 1/Phase 2
Recruiting

Primary endpoint: Objective Response Rate (ORR)

InterventionalRandomizedopen518 targetStarted 2020-11Completion 2027-0933 sites · China, France, Israel, New Zealand…Hoffmann-La Roche

Frequently asked questions

Who is developing amezalpat?

amezalpat is being developed by Tempest Therapeutics, Inc..

How many clinical trials involve amezalpat?

BioSniper tracks 2 clinical trials involving amezalpat.