| ALNYALNYLAM PHARMACEUTICALS, INC. | 85,241 | $28.2M |
| REGNREGENERON PHARMACEUTICALS, INC. | 18,602 | $14.4M |
| GILDGILEAD SCIENCES, INC. | 56,928 | $7.9M |
| EXELEXELIXIS, INC. | 90,140 | $3.9M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 55,546 | $3.5M |
| SNYSanofi | 60,025 | $2.9M |
| AVTXAvalo Therapeutics, Inc. | 125,195 | $1.9M |
| ADMAADMA BIOLOGICS, INC. | 204,475 | $1.8M |
| RVMDREVOLUTION MEDICINES, INC. | 16,667 | $1.6M |
| JAZZJazz Pharmaceuticals plc | 7,796 | $1.5M |
| VKTXViking Therapeutics, Inc. | 40,131 | $1.3M |
| PVLAPALVELLA THERAPEUTICS, INC. | 8,232 | $1.0M |
| NTLAIntellia Therapeutics, Inc. | 75,032 | $962K |
| TVTXTravere Therapeutics, Inc. | 31,729 | $943K |
| GMABGenmab A/S | 33,399 | $896K |
| XOMAXOMA Royalty Corporation | 28,495 | $894K |
| CLDXCelldex Therapeutics, Inc. | 24,440 | $775K |
| KALVKalVista Pharmaceuticals, Inc. | 35,123 | $707K |
| PGENPRECIGEN, INC. | 179,359 | $694K |
| RCUSArcus Biosciences, Inc. | 32,108 | $694K |
| OCSOculis Holding AG | 25,482 | $678K |
| TGTXTG THERAPEUTICS, INC. | 18,877 | $627K |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 11,501 | $594K |
| IMCRImmunocore Holdings plc | 19,254 | $581K |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 158,929 | $558K |
| ARQTArcutis Biotherapeutics, Inc. | 23,157 | $546K |
| BMRNBIOMARIN PHARMACEUTICAL INC | 9,492 | $536K |
| FBRXForte Biosciences, Inc. | 18,622 | $482K |
| IVAInventiva S.A. | 84,323 | $468K |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 8,425 | $465K |
| ZYMEZymeworks Inc. | 16,735 | $419K |
| PHVSPharvaris N.V. | 13,723 | $388K |
| ASRTAssertio Holdings, Inc. | 18,687 | $356K |
| GERNGERON CORP | 232,332 | $346K |
| STOKStoke Therapeutics, Inc. | 10,293 | $335K |
| FLGTFulgent Genetics Inc. | 19,640 | $312K |
| GRCEGrace Therapeutics, Inc. | 66,822 | $309K |
| FDMT4D Molecular Therapeutics, Inc. | 32,524 | $303K |
| KODKodiak Sciences Inc. | 7,868 | $300K |
| MESOMesoblast Limited | 17,247 | $265K |
| OVIDOvid Therapeutics Inc. | 111,804 | $248K |
| TENXTENAX THERAPEUTICS, INC. | 15,472 | $247K |
| LBRXLB PHARMACEUTICALS INC | 9,931 | $245K |
| CAPRCAPRICOR THERAPEUTICS, INC. | 7,900 | $240K |
| TNXPTonix Pharmaceuticals Holding Corp. | 17,410 | $239K |
| KRROKorro Bio, Inc. | 20,356 | $230K |
| TRDAEntrada Therapeutics, Inc. | 17,538 | $221K |
| CRBPCorbus Pharmaceuticals Holdings, Inc. | 22,986 | $216K |
| RLAYRelay Therapeutics, Inc. | 21,123 | $210K |
| AVXLANAVEX LIFE SCIENCES CORP. | 60,336 | $185K |
| ELTXElicio Therapeutics, Inc. | 16,912 | $181K |
| MISTMilestone Pharmaceuticals Inc. | 149,105 | $177K |
| LXRXLEXICON PHARMACEUTICALS, INC. | 110,379 | $172K |
| ADPTAdaptive Biotechnologies Corp | 12,387 | $172K |
| CCCCC4 Therapeutics, Inc. | 62,760 | $165K |
| CGEMCullinan Therapeutics, Inc. | 10,577 | $150K |
| DMACDiaMedica Therapeutics Inc. | 22,039 | $149K |
| FATEFATE THERAPEUTICS INC | 120,343 | $144K |
| SABSSAB BIOTHERAPEUTICS, INC. | 35,264 | $135K |
| ABCLAbCellera Biologics Inc. | 37,972 | $133K |
| BBOTBridgeBio Oncology Therapeutics, Inc. | 13,351 | $119K |
| SVRASavara Inc | 21,344 | $117K |
| PBYIPUMA BIOTECHNOLOGY, INC. | 16,745 | $107K |
| CADLCandel Therapeutics, Inc. | 21,023 | $103K |
| IVVDInvivyd, Inc. | 78,433 | $102K |
| OPKOPKO HEALTH, INC. | 88,937 | $101K |
| KURAKura Oncology, Inc. | 12,227 | $99K |
| CMPSCOMPASS Pathways plc | 17,891 | $99K |
| SPROSpero Therapeutics, Inc. | 40,128 | $94K |
| ANNXAnnexon, Inc. | 16,903 | $94K |
| RLMDRELMADA THERAPEUTICS, INC. | 12,498 | $87K |
| ALGSAligos Therapeutics, Inc. | 10,822 | $80K |
| BDTXBlack Diamond Therapeutics, Inc. | 37,474 | $80K |
| ZNTLZentalis Pharmaceuticals, Inc. | 33,332 | $78K |
| AUTLAutolus Therapeutics plc | 54,733 | $76K |
| CMPXCompass Therapeutics, Inc. | 13,845 | $73K |
| BMEABiomea Fusion, Inc. | 46,162 | $71K |
| PLRXPLIANT THERAPEUTICS, INC. | 50,981 | $64K |
| ALVOAlvotech | 16,412 | $56K |
| ADAGAdagene Inc. | 11,617 | $46K |
| ALECAlector, Inc. | 19,486 | $42K |
| SANASana Biotechnology, Inc. | 14,004 | $40K |
| IMUXIMMUNIC, INC. | 29,627 | $33K |
| CHRSCoherus Oncology, Inc. | 17,775 | $30K |
| PRQRProQR Therapeutics N.V. | 12,035 | $19K |
| IMMPImmutep Limited | 26,910 | $9K |