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Opaleye Management Inc.

Source: SEC Form 13F · as of Mar 2026

Opaleye Management Inc. holds 31 biotech & pharma companies tracked by BioSniper, totaling $288.1M in value as of Mar 2026 (SEC Form 13F).

Companies held

31

Total value held

$288.1M

BioSniper AIPage evidence connected

Prepared research question

What matters most for RHYTHM PHARMACEUTICALS, INC. (RYTM)—catalysts, financial risk and supporting evidence?

Run cited research

Traceable citations · Unknowns marked

CompanySharesValue
RYTMRHYTHM PHARMACEUTICALS, INC.123,000$35.3M
APGEApogee Therapeutics, Inc.390,000$32.8M
IRONDisc Medicine, Inc.421,000$26.9M
URGNUroGen Pharma Ltd.1,430,000$25.7M
STOKStoke Therapeutics, Inc.700,000$22.8M
TGTXTG THERAPEUTICS, INC.535,000$17.8M
EWTXEdgewise Therapeutics, Inc.500,000$15.8M
ANNXAnnexon, Inc.2,331,761$12.9M
ALMSALUMIS INC.550,000$12.1M
PTGXProtagonist Therapeutics, Inc100,000$10.5M
RVMDREVOLUTION MEDICINES, INC.100,000$9.7M
MBXMBX Biosciences, Inc.260,000$7.8M
RLMDRELMADA THERAPEUTICS, INC.935,000$6.5M
CGONCG Oncology, Inc.94,800$6.4M
JBIOJade Biosciences, Inc.427,608$6.0M
OCULOCULAR THERAPEUTIX, INC600,000$5.1M
STROSUTRO BIOPHARMA, INC.190,671$4.7M
TRVITrevi Therapeutics, Inc.345,100$4.1M
TECXTectonic Therapeutic, Inc.123,000$3.8M
CABACabaletta Bio, Inc.1,380,000$3.7M
RCKTRocket Pharmaceuticals Inc.955,000$3.4M
NTLAIntellia Therapeutics, Inc.245,000$3.1M
IRDOpus Genetics, Inc.1,120,000$2.3M
RIGLRIGEL PHARMACEUTICALS INC70,000$1.9M
AVIRAtea Pharmaceuticals, Inc.322,600$1.7M
LYELLyell Immunopharma, Inc.79,097$1.6M
ENTAENANTA PHARMACEUTICALS INC125,000$1.6M
FDMT4D Molecular Therapeutics, Inc.112,291$1.0M
BBOTBridgeBio Oncology Therapeutics, Inc.53,282$477K
LBRXLB PHARMACEUTICALS INC14,506$358K
ADGMAdagio Medical Holdings Inc18,444$21K

13F holdings reflect long positions in U.S.-listed securities as reported to the SEC. Values are point-in-time for the most recent reported quarter.