| GILDGILEAD SCIENCES, INC. | 1,450,177 | $202.1M |
| REGNREGENERON PHARMACEUTICALS, INC. | 58,925 | $45.5M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 105,859 | $35.0M |
| AXSMAxsome Therapeutics, Inc. | 56,633 | $9.6M |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 146,462 | $9.2M |
| GSKGSK plc American Depositary Shares (Each representing two Ordinary Shares) | 124,002 | $6.8M |
| TEVATeva Pharmaceutical Industries Limited | 224,067 | $6.7M |
| EXELEXELIXIS, INC. | 156,765 | $6.7M |
| DRTSAlpha Tau Medical Ltd. | 874,994 | $6.2M |
| ARGXARGENX SE | 5,298 | $3.9M |
| BBIOBridgeBio Pharma, Inc. | 47,624 | $3.5M |
| SNYSanofi | 64,096 | $3.1M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 47,276 | $2.7M |
| INCYIncyte Corp. | 25,989 | $2.4M |
| LGNDLigand Pharmaceuticals Incorporated | 11,133 | $2.2M |
| JAZZJazz Pharmaceuticals plc | 8,035 | $1.5M |
| IMVTImmunovant, Inc. | 56,744 | $1.4M |
| MRNAModerna, Inc. | 26,175 | $1.3M |
| CYTKCYTOKINETICS INC | 16,631 | $1.1M |
| ROIVRoivant Sciences Ltd. | 33,664 | $932K |
| ZYMEZymeworks Inc. | 36,262 | $908K |
| TGTXTG THERAPEUTICS, INC. | 25,273 | $840K |
| INVAInnoviva, Inc. | 35,595 | $829K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 9,058 | $788K |
| SUPNSUPERNUS PHARMACEUTICALS, INC. | 14,810 | $766K |
| INSMINSMED Inc | 3,897 | $637K |
| PTGXProtagonist Therapeutics, Inc | 5,386 | $568K |
| RDYDR REDDYS LABORATORIES LTD | 34,258 | $474K |
| GPCRStructure Therapeutics Inc. | 9,620 | $464K |
| PTCTPTC THERAPEUTICS, INC. | 6,775 | $462K |
| PGENPRECIGEN, INC. | 114,152 | $442K |
| AQSTAquestive Therapeutics, Inc. | 104,652 | $434K |
| IBRXImmunityBio, Inc. | 55,880 | $429K |
| GMABGenmab A/S | 15,433 | $414K |
| KNSAKiniksa Pharmaceuticals International, plc | 8,585 | $413K |
| ESPREsperion Therapeutics, Inc. | 141,152 | $387K |
| HRMYHarmony Biosciences Holdings, Inc. | 13,323 | $373K |
| DFTXDefinium Therapeutics Inc. | 18,559 | $351K |
| ABCLAbCellera Biologics Inc. | 95,933 | $335K |
| CNTXContext Therapeutics Inc. | 126,152 | $331K |
| HROWHARROW, INC. | 9,319 | $329K |
| OGNOrganon & Co. | 49,019 | $294K |
| IONSIONIS PHARMACEUTICALS INC | 3,797 | $285K |
| KYNBKYNTRA BIO INC. | 39,744 | $269K |
| GALTGALECTIN THERAPEUTICS INC | 93,375 | $261K |
| RVMDREVOLUTION MEDICINES, INC. | 2,550 | $248K |
| BEAMBeam Therapeutics Inc. | 10,088 | $240K |
| DNLIDenali Therapeutics Inc. | 11,971 | $230K |
| GHRSGH Research PLC | 15,600 | $219K |
| ANIPANI PHARMACEUTICALS INC | 2,802 | $215K |
| SPRYARS Pharmaceuticals, Inc. | 25,413 | $204K |
| CSBRCHAMPIONS ONCOLOGY, INC. | 35,158 | $202K |
| GERNGERON CORP | 117,329 | $175K |
| SGMOQSANGAMO THERAPEUTICS, INC | 706,481 | $174K |
| LRMRLarimar Therapeutics, Inc. | 38,465 | $173K |
| CMPSCOMPASS Pathways plc | 30,641 | $169K |
| LCTXLineage Cell Therapeutics, Inc. | 99,870 | $158K |
| ADMAADMA BIOLOGICS, INC. | 16,222 | $146K |
| NTLAIntellia Therapeutics, Inc. | 11,198 | $144K |
| ATAIAtai Beckley N.V. | 38,138 | $135K |
| NUVBNuvation Bio Inc. | 28,198 | $121K |
| ELTXElicio Therapeutics, Inc. | 11,166 | $119K |
| GRFSGrifols S.A. | 14,604 | $117K |
| ANIXAnixa Biosciences Inc | 41,550 | $107K |
| RLAYRelay Therapeutics, Inc. | 10,738 | $107K |
| FENCFENNEC PHARMACEUTICALS INC. | 14,960 | $92K |
| CATXPerspective Therapeutics, Inc. | 20,027 | $84K |
| DMACDiaMedica Therapeutics Inc. | 10,999 | $74K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 23,679 | $73K |
| TTRXTurn Therapeutics Inc. | 19,684 | $63K |
| CRDFCardiff Oncology, Inc. | 34,166 | $55K |
| BTAIBioXcel Therapeutics, Inc. | 41,000 | $55K |
| LSTALISATA THERAPEUTICS, INC. | 10,042 | $50K |
| CYPHCYPHERPUNK TECHNOLOGIES INC. | 60,500 | $48K |
| CRVOCervoMed Inc. | 11,265 | $44K |
| FATEFATE THERAPEUTICS INC | 35,322 | $42K |
| OPKOPKO HEALTH, INC. | 33,311 | $38K |
| HURATuHURA Biosciences, Inc./NV | 21,152 | $38K |
| ALECAlector, Inc. | 10,760 | $23K |
| BRNSBarinthus Biotherapeutics plc. | 37,450 | $21K |
| INOINOVIO PHARMACEUTICALS, INC. | 11,899 | $21K |
| CGTXCOGNITION THERAPEUTICS INC | 24,000 | $18K |
| HRTXHERON THERAPEUTICS, INC. /DE/ | 17,612 | $14K |
| HUMAHumacyte Inc. | 23,085 | $14K |
| RNTXRein Therapeutics, Inc. | 10,000 | $13K |
| MISTMilestone Pharmaceuticals Inc. | 10,000 | $12K |
| VTGNVistagen Therapeutics, Inc. | 20,628 | $12K |
| IGCIGC Pharma, Inc. | 10,000 | $3K |