| UTHRUNITED THERAPEUTICS Corp | 87,503 | $51.9M |
| VRTXVERTEX PHARMACEUTICALS INC / MA | 96,940 | $43.3M |
| VKTXViking Therapeutics, Inc. | 1,184,381 | $38.5M |
| CAPRCAPRICOR THERAPEUTICS, INC. | 1,031,551 | $31.4M |
| ABVXAbivax SA | 275,944 | $30.5M |
| LQDALiquidia Corp | 712,100 | $26.9M |
| RVMDREVOLUTION MEDICINES, INC. | 206,372 | $20.1M |
| APGEApogee Therapeutics, Inc. | 222,500 | $18.7M |
| INCYIncyte Corp. | 183,429 | $17.3M |
| KODKodiak Sciences Inc. | 440,062 | $16.8M |
| CYTKCYTOKINETICS INC | 250,000 | $16.5M |
| JNJJOHNSON & JOHNSON | 53,771 | $13.1M |
| COGTCogent Biosciences, Inc. | 322,764 | $12.4M |
| MRKMerck & Co., Inc. | 100,000 | $12.0M |
| JAZZJazz Pharmaceuticals plc | 54,755 | $10.4M |
| GPCRStructure Therapeutics Inc. | 199,734 | $9.6M |
| TERNTerns Pharmaceuticals, Inc. | 181,752 | $9.6M |
| QUREuniQure N.V. | 580,200 | $9.5M |
| ROIVRoivant Sciences Ltd. | 335,800 | $9.3M |
| BMRNBIOMARIN PHARMACEUTICAL INC | 148,229 | $8.4M |
| MRNAModerna, Inc. | 159,400 | $8.1M |
| TGTXTG THERAPEUTICS, INC. | 206,928 | $6.9M |
| CORTCORCEPT THERAPEUTICS INC | 168,500 | $6.8M |
| EWTXEdgewise Therapeutics, Inc. | 212,500 | $6.7M |
| BBIOBridgeBio Pharma, Inc. | 85,311 | $6.3M |
| REPLReplimune Group, Inc. | 766,060 | $5.9M |
| IMCRImmunocore Holdings plc | 193,189 | $5.8M |
| LLYELI LILLY & Co | 6,000 | $5.5M |
| ABBVAbbVie Inc. | 24,058 | $5.2M |
| CRBPCorbus Pharmaceuticals Holdings, Inc. | 555,257 | $5.2M |
| RCUSArcus Biosciences, Inc. | 238,142 | $5.1M |
| CRVSCorvus Pharmaceuticals, Inc. | 351,111 | $5.1M |
| CRSPCRISPR Therapeutics AG | 106,300 | $5.1M |
| PCVXVaxcyte, Inc. | 78,171 | $4.5M |
| ZYMEZymeworks Inc. | 142,132 | $3.6M |
| GLUEMonte Rosa Therapeutics, Inc. | 187,307 | $3.1M |
| ALMSALUMIS INC. | 131,200 | $2.9M |
| ANNXAnnexon, Inc. | 486,116 | $2.7M |
| BHVNBiohaven Ltd. | 317,000 | $2.7M |
| HRMYHarmony Biosciences Holdings, Inc. | 92,864 | $2.6M |
| NVONovo Nordisk A/S | 70,477 | $2.6M |
| NTLAIntellia Therapeutics, Inc. | 200,000 | $2.6M |
| VYGRVoyager Therapeutics, Inc. | 573,642 | $2.2M |
| BCYCBICYCLE THERAPEUTICS PLC | 476,424 | $2.2M |
| INDVIndivior Pharmaceuticals, Inc. | 71,376 | $2.2M |
| CLYMClimb Bio, Inc. | 286,126 | $2.0M |
| IVAInventiva S.A. | 352,399 | $1.9M |
| TARSTarsus Pharmaceuticals, Inc. | 25,942 | $1.8M |
| ALKSAlkermes plc. | 50,000 | $1.8M |
| MGNXMACROGENICS INC | 600,000 | $1.7M |
| CTMXCytomX Therapeutics, Inc. | 316,000 | $1.5M |
| AVXLANAVEX LIFE SCIENCES CORP. | 477,600 | $1.5M |
| RLMDRELMADA THERAPEUTICS, INC. | 200,842 | $1.4M |
| KPTIKaryopharm Therapeutics Inc. | 241,300 | $1.3M |
| SLSSELLAS Life Sciences Group, Inc. | 300,000 | $1.3M |
| OLMAOlema Pharmaceuticals, Inc. | 84,000 | $1.3M |
| CRMDCorMedix Inc. | 167,500 | $1.1M |
| INOINOVIO PHARMACEUTICALS, INC. | 637,865 | $1.1M |
| IOVAIOVANCE BIOTHERAPEUTICS, INC. | 302,900 | $1.1M |
| BIOABioAge Labs, Inc. | 60,000 | $1.0M |
| AYTUAYTU BIOPHARMA, INC | 353,077 | $964K |
| OCGNOcugen, Inc. | 500,000 | $905K |
| EQEquillium, Inc. | 433,844 | $868K |
| DNTHDianthus Therapeutics, Inc. /DE/ | 10,000 | $839K |
| PHVSPharvaris N.V. | 29,321 | $828K |
| ENTAENANTA PHARMACEUTICALS INC | 64,952 | $820K |
| IBRXImmunityBio, Inc. | 106,300 | $815K |
| VIRVir Biotechnology, Inc. | 88,800 | $796K |
| XERSXeris Biopharma Holdings, Inc. | 132,746 | $770K |
| LRMRLarimar Therapeutics, Inc. | 166,637 | $750K |
| RAREUltragenyx Pharmaceutical Inc. | 35,144 | $736K |
| MLYSMineralys Therapeutics, Inc. | 26,347 | $714K |
| UNCYUnicycive Therapeutics, Inc. | 106,083 | $698K |
| SPRBSPRUCE BIOSCIENCES, INC. | 10,000 | $654K |
| PHATPhathom Pharmaceuticals, Inc. | 54,650 | $607K |
| CNTBConnect Biopharma Holdings Ltd | 200,690 | $526K |
| PTHSPelthos Therapeutics Inc. | 24,773 | $520K |
| EOLSEvolus, Inc. | 125,200 | $515K |
| MNKDMANNKIND CORP | 186,603 | $457K |
| MAZEMaze Therapeutics, Inc. | 15,000 | $448K |
| JANXJanux Therapeutics, Inc. | 31,600 | $439K |
| URGNUroGen Pharma Ltd. | 23,155 | $416K |
| LPCNLipocine Inc. | 50,000 | $400K |
| FHTXFoghorn Therapeutics Inc. | 79,944 | $382K |
| GHRSGH Research PLC | 26,836 | $377K |
| PRQRProQR Therapeutics N.V. | 180,083 | $292K |
| EPRXEUPRAXIA PHARMACEUTICALS INC. | 40,000 | $290K |
| PEPGPepGen Inc. | 150,925 | $267K |
| TRVITrevi Therapeutics, Inc. | 21,663 | $258K |
| PGENPRECIGEN, INC. | 55,293 | $214K |
| UPBUpstream Bio, Inc. | 21,609 | $194K |
| CMPSCOMPASS Pathways plc | 31,885 | $176K |
| PASGPassage BIO, Inc. | 19,530 | $153K |
| TLPHTALPHERA, INC. | 153,563 | $115K |
| RCKTRocket Pharmaceuticals Inc. | 30,579 | $109K |
| MNPRMonopar Therapeutics | 1,630 | $89K |
| LYELLyell Immunopharma, Inc. | 4,100 | $82K |
| VTGNVistagen Therapeutics, Inc. | 105,428 | $60K |
| RNAAtrium Therapeutics Inc. | 2,512 | $34K |
| ATYRaTYR PHARMA INC | 24,700 | $19K |
| PRTCPureTech Health plc | 7,924 | $11K |
| ELVNEnliven Therapeutics, Inc. | 245 | $10K |
| SEPNSepterna, Inc. | 202 | $5K |
| JBIOJade Biosciences, Inc. | 1,046 | $3K |