| ARGXARGENX SE | 313,000 | $228.6M |
| REGNREGENERON PHARMACEUTICALS, INC. | 278,674 | $215.3M |
| SRRKScholar Rock Holding Corp | 3,584,573 | $176.2M |
| GILDGILEAD SCIENCES, INC. | 1,169,879 | $163.0M |
| RVMDREVOLUTION MEDICINES, INC. | 1,544,456 | $150.2M |
| IONSIONIS PHARMACEUTICALS INC | 1,818,665 | $136.6M |
| VRDNViridian Therapeutics, Inc.\DE | 6,726,144 | $131.6M |
| NUVLNuvalent, Inc. | 1,053,268 | $107.9M |
| ELVNEnliven Therapeutics, Inc. | 2,320,867 | $91.0M |
| IMCRImmunocore Holdings plc | 2,796,803 | $84.3M |
| ALNYALNYLAM PHARMACEUTICALS, INC. | 234,543 | $77.6M |
| PCVXVaxcyte, Inc. | 1,190,697 | $69.2M |
| DMRADamora Therapeutics, Inc. | 2,298,000 | $59.5M |
| TNGXTango Therapeutics, Inc. | 2,400,000 | $50.2M |
| JBIOJade Biosciences, Inc. | 3,501,502 | $49.2M |
| CLDXCelldex Therapeutics, Inc. | 1,200,000 | $38.1M |
| IRONDisc Medicine, Inc. | 459,314 | $29.4M |
| ANNXAnnexon, Inc. | 5,157,290 | $28.6M |
| ORKAOruka Therapeutics, Inc. | 507,008 | $24.9M |
| TEVATeva Pharmaceutical Industries Limited | 250,082 | $7.5M |
| RNAAtrium Therapeutics Inc. | 263,096 | $3.5M |
| BBIOBridgeBio Pharma, Inc. | 25,377 | $1.9M |
| INSMINSMED Inc | 10,034 | $1.6M |
| PTGXProtagonist Therapeutics, Inc | 14,447 | $1.5M |
| ONCBeOne Medicines Ltd. | 3,812 | $1.1M |
| ADPTAdaptive Biotechnologies Corp | 76,181 | $1.1M |
| NAMSNEWAMSTERDAM PHARMA CO N.V. | 27,661 | $885K |
| CYTKCYTOKINETICS INC | 8,841 | $583K |
| AXSMAxsome Therapeutics, Inc. | 3,181 | $538K |
| AGMBAgomAb Therapeutics NV | 50,000 | $525K |
| CNTACentessa Pharmaceuticals plc | 9,030 | $359K |
| DNLIDenali Therapeutics Inc. | 17,766 | $341K |
| GPCRStructure Therapeutics Inc. | 6,803 | $328K |
| SMMTSummit Therapeutics Inc. | 15,858 | $301K |
| TVTXTravere Therapeutics, Inc. | 8,899 | $264K |
| OLMAOlema Pharmaceuticals, Inc. | 16,443 | $245K |
| PTCTPTC THERAPEUTICS, INC. | 1,935 | $132K |
| ABVXAbivax SA | 1,048 | $117K |
| ARWRARROWHEAD PHARMACEUTICALS, INC. | 1,545 | $97K |
| RYTMRHYTHM PHARMACEUTICALS, INC. | 1,016 | $88K |
| BBOTBridgeBio Oncology Therapeutics, Inc. | 6,982 | $62K |
| INCYIncyte Corp. | 486 | $46K |
| RXRXRECURSION PHARMACEUTICALS, INC. | 4,627 | $14K |