zongertinib
zongertinib: 2 clinical trials tracked.
zongertinib evidence translation
What we can confirm
2 tracked trials
What it means
What to watch
Prepared research question
What is verified about zongertinib, and what remains unknown?
Traceable citations · Unknowns marked
Clinical Trial Registry Records (2)
Beamion LUNG-3: A Randomized, Controlled, Multi-center Trial Evaluating Zongertinib as an Adjuvant Monotherapy Compared With Standard of Care in Patients With Early-stage, Resectable Non-small Cell Lung Cancer (Stage II-IIIB) Harboring Tyrosine Kinase Domain Activating HER2 Mutations
Primary endpoint: Disease-free survival (DFS) by investigator's assessment
Beamion LUNG 2: A Phase III, Open-label, Randomized, Active-controlled, Multi-centre Trial Evaluating Orally Administered Zongertinib (BI 1810631) Compared With Standard of Care as First-line Treatment in Patients With Unresectable, Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer Harbouring HER2 Tyrosine Kinase Domain Mutations
Primary endpoint: Progression-free survival (PFS) according to Response Evaluation Criteria in Solid Tumours (RECIST) 1.1 determined by blinded central independent review