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zipalertinib

Generic: zipalertinib·Code: CLN-081, TAS6417

zipalertinib: sourced relationships with 1 company · 1 clinical trial tracked.

zipalertinib evidence translation

What we can confirm

What it means

Source-backed records connect zipalertinib to CGEM; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could zipalertinib → CGEM affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 0 study sponsors

Related indications

EGFR exon 20 (EGFRex20) insertion non-small-cell lung cancer (NSCLC); being evaluated in patients who progressed after prior systemic therapy and in previously untreated advanced EGFRex20 NSCLC (first-line in combination with chemotherapy); also evaluated in cohorts including treatment-naïve, prior treated, and patients with active brain metastases

Study sponsors

No additional listed-company sponsor is linked.

Dated Pipeline Records (1)
CompanyDated record stage
Cullinan Therapeutics, Inc. (CGEM)
co_developer · Reported 2024-03-14 · Current development: unknownSource
EGFR exon 20 (EGFRex20) insertion non-small-cell lung cancer…
Phase 3
Clinical Trial Registry Records (1)

An Open-Label, Phase 2b, Global Multicenter Cohort Trial to Assess the Safety and Efficacy of Zipalertinib in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Exon 20 Insertion and Uncommon/Single or Compound Epidermal Growth Factor Receptor Mutations.

NCT05967689Registry updated 2026-09-01·Phase 2
Recruiting

Primary endpoint: Cohorts 1-4: Objective Response Rate (ORR)

InterventionalRandomizedopen220 targetStarted 2023-07Completion 2028-1250 sites · Australia, Canada, France, Germany…Taiho Oncology, Inc.

Frequently asked questions

Which companies have sourced relationships with zipalertinib?

zipalertinib has dated SEC/FDA relationship records for Cullinan Therapeutics, Inc..

How many clinical trials involve zipalertinib?

BioSniper tracks 1 clinical trial involving zipalertinib.