zilucoplan
zilucoplan: developed by 1 company · 5 clinical trials tracked.
zilucoplan evidence translation
What we can confirm
5 tracked trials
What it means
What to watch
Prepared research question
How could zilucoplan → RARX affect its developer, and what evidence supports the link?
Traceable citations · Unknowns marked
See linked entities and source evidence3 indications · 2 study sponsors
Development Pipeline (1)
| Company | Phase |
|---|---|
| RA PHARMACEUTICALS, INC. (RARX) | Phase 3 |
Clinical Trials (5)
A Multicenter Open-Label, Uncontrolled Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Activity of Zilucoplan in Pediatric Study Participants From 2 to Less Than 18 Years of Age With Acetylcholine Receptor Antibody Positive Generalized Myasthenia Gravis
Primary endpoint: Plasma concentrations of zilucoplan (ZLP) sampled at Week 4 (Day 29)
A Phase 3b, Multicenter, Open-Label, Single-Arm Study to Evaluate the Safety, Tolerability, and Efficacy of Zilucoplan in Participants With Generalized Myasthenia Gravis Switching From Intravenous Complement Component 5 Inhibitors to Subcutaneous Zilucoplan
Primary endpoint: Percentage of Participants With Treatment-emergent Adverse Events (TEAEs) Over the Main Treatment Period
HEALEY ALS Platform Trial
Primary endpoint: Disease Progression
A Phase 3, Multicenter, Open-Label Extension Study of Zilucoplan in Subjects With Generalized Myasthenia Gravis
Primary endpoint: Incidence of treatment-emergent adverse events (TEAEs)
A Phase 3, Multicenter, Randomized, Double Blind, Placebo-Controlled Study to Confirm the Safety, Tolerability, and Efficacy of Zilucoplan in Subjects With Generalized Myasthenia Gravis
Primary endpoint: Change From Baseline (CFB) to Week 12 in Myasthenia Gravis-Activities of Daily Living (MG-ADL) Total Score
Frequently asked questions
Who is developing zilucoplan?
zilucoplan is being developed by RA PHARMACEUTICALS, INC..
How many clinical trials involve zilucoplan?
BioSniper tracks 5 clinical trials involving zilucoplan.