Skip to main content

vobramitamab duocarmazine

Generic: Vobramitamab Duocarmazine

vobramitamab duocarmazine: 4 clinical trials tracked.

vobramitamab duocarmazine evidence translation

What we can confirm

4 tracked trials

No verified listed developer

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about vobramitamab duocarmazine, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 1 study sponsors
Clinical Trials (4)

A Phase II Study of MGC018 in Patients With Relapsed or Refractory Extensive-Stage Small-Cell Lung Cancer (ES-SCLC)

NCT06227546·Phase 2
Active, not recruiting

Primary endpoint: Objective Response Rate (ORR)

Interventionalopen9 targetStarted 2024-04Completion 2027-041 site · United StatesGeorgetown University

A Phase 2, Open-label, Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration-resistant Prostate Cancer and Other Solid Tumors

NCT05551117·Phase 2·MGNX
Terminated

Primary endpoint: Part 1: Six-month Radiographic Progression Free Survival (rPFS) as Determined by the Investigator

InterventionalRandomizedopen192 targetStarted 2023-06Completion 2025-0150 sites · Australia, Belgium, France, Italy…MacroGenics

A Phase 1/1b Dose Escalation and Cohort Expansion Study of MGC018 in Combination With Checkpoint Inhibitor in Participants With Advanced Solid Tumors

NCT05293496·Phase 1·MGNX
Completed

Primary endpoint: Number of participants with adverse events (AEs)

Interventionalopen31 enrolledStarted 2022-04Completion 2025-0810 sites · United StatesMacroGenics

A Phase 1/2, First-in-Human, Open-Label, Dose-Escalation Study of MGC018 (Anti-B7-H3 Antibody Drug Conjugate) Alone and in Combination With MGA012 (Anti-PD-1 Antibody) in Patients With Advanced Solid Tumors

NCT03729596·Phase 1·MGNX
Terminated

Primary endpoint: Number of Patients With Adverse Events of Vobramitamab Duocarmazine as Assessed by CTCAE v4.03

Interventionalopen143 targetStarted 2018-11Completion 2023-0321 sites · Australia, Poland, Spain, United StatesMacroGenics