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vobramitamab duocarmazine

Generic: Vobramitamab Duocarmazine

vobramitamab duocarmazine: 4 clinical trials tracked.

vobramitamab duocarmazine evidence translation

What we can confirm

4 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about vobramitamab duocarmazine, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 1 study sponsors
Clinical Trial Registry Records (4)

A Phase II Study of MGC018 in Patients With Relapsed or Refractory Extensive-Stage Small-Cell Lung Cancer (ES-SCLC)

NCT06227546Registry updated 2026-06-25·Phase 2
Active, not recruiting

Primary endpoint: Objective Response Rate (ORR)

Interventionalopen9 targetStarted 2024-04Completion 2027-041 site · United StatesGeorgetown University

A Phase 2, Open-label, Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration-resistant Prostate Cancer and Other Solid Tumors

NCT05551117Registry updated 2026-02-09·Phase 2·MGNX
Terminated

Primary endpoint: Part 1: Six-month Radiographic Progression Free Survival (rPFS) as Determined by the Investigator

InterventionalRandomizedopen192 targetStarted 2023-06Completion 2025-0150 sites · Australia, Belgium, France, Italy…MacroGenics

A Phase 1/1b Dose Escalation and Cohort Expansion Study of MGC018 in Combination With Checkpoint Inhibitor in Participants With Advanced Solid Tumors

NCT05293496Registry updated 2025-10-14·Phase 1·MGNX
Completed

Primary endpoint: Number of participants with adverse events (AEs)

Interventionalopen31 enrolledStarted 2022-04Completion 2025-0810 sites · United StatesMacroGenics

A Phase 1/2, First-in-Human, Open-Label, Dose-Escalation Study of MGC018 (Anti-B7-H3 Antibody Drug Conjugate) Alone and in Combination With MGA012 (Anti-PD-1 Antibody) in Patients With Advanced Solid Tumors

NCT03729596Registry updated 2025-07-31·Phase 1·MGNX
Terminated

Primary endpoint: Number of Patients With Adverse Events of Vobramitamab Duocarmazine as Assessed by CTCAE v4.03

Interventionalopen143 targetStarted 2018-11Completion 2023-0321 sites · Australia, Poland, Spain, United StatesMacroGenics