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verekitug

verekitug: developed by 1 company · 4 clinical trials tracked.

verekitug evidence translation

What we can confirm

4 tracked trials

What it means

Source-backed records connect verekitug to UPB; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could verekitug → UPB affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence4 indications · 0 study sponsors

Related indications

Severe Asthma; Chronic Obstructive Pulmonary Disease; Chronic Rhinosinusitis With Nasal PolypsChronic Obstructive Pulmonary DiseaseChronic Rhinosinusitis With Nasal PolypsSevere Asthma

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
Upstream Bio, Inc. (UPB)
Severe Asthma; Chronic Obstructive Pulmonary Disease; Chroni…
Phase 2
Clinical Trials (4)

A Phase 2b Randomized, Double-blind, Placebo-controlled, Parallel-Group Study to Assess Efficacy and Safety of Verekitug (UPB-101) in Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

NCT06981078·Phase 2·UPB
Active, not recruiting

Primary endpoint: Annualized rate of moderate or severe COPD exacerbation events

InterventionalRandomizedquadruple666 targetStarted 2025-07Completion 2027-1150 sites · Argentina, Bulgaria, United StatesUpstream Bio Inc.

A Long-Term Extension Study to Evaluate Safety and Efficacy of Verekitug (UPB-101) in Adult Participants With Severe Asthma Who Completed the VALIANT Trial

NCT06966479·Phase 2·UPB
Active, not recruiting

Primary endpoint: Number of Participants with Adverse Events (AEs) and Serious Adverse Events (SAEs)

InterventionalRandomizedquadruple396 targetStarted 2025-05Completion 2027-0950 sites · Argentina, Bulgaria, Canada, Chile…Upstream Bio Inc.

A Phase 2, Randomized, Double-blind, Placebo-controlled, Multi-center, Dose-ranging Study to Evaluate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT)

NCT06196879·Phase 2·UPB
Completed

Primary endpoint: Annual Asthma Exacerbation Rate (AAER)

InterventionalRandomizedquadruple479 enrolledStarted 2024-02Completion 2026-0350 sites · United StatesUpstream Bio Inc.

A Phase 2, Randomized, Double-blind, Placebo-controlled, Multi-center Study to Assess the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps on a Background of Nasal Corticosteroids (VIBRANT)

NCT06164704·Phase 2·UPB
Completed

Primary endpoint: Change From Baseline in Nasal Polyp Score (NPS) at Week 24

InterventionalRandomizedquadruple81 enrolledStarted 2023-12Completion 2025-0741 sites · Czechia, Germany, Poland, Spain…Upstream Bio Inc.

Frequently asked questions

Who is developing verekitug?

verekitug is being developed by Upstream Bio, Inc..

How many clinical trials involve verekitug?

BioSniper tracks 4 clinical trials involving verekitug.