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tranexamic acid

Generic: TRANEXAMIC ACID·Brand: CYKLOKAPRON, Cyklokapron, LYSTEDA, Lysteda, TRANEXAMIC ACID

tranexamic acid: developed by 1 company · 7 clinical trials tracked · 1 FDA decision.

tranexamic acid evidence translation

What we can confirm

1 FDA record · 7 tracked trials

What it means

Source-backed records connect tranexamic acid to NEXS; that link alone does not prove the drug works.

What to watch

Watch active trials and any change in FDA or trial status.
BioSniper AIPage evidence connected

Prepared research question

How could tranexamic acid → NEXS affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 2 study sponsors
Development Pipeline (2)
CompanyPhase
NEXUS BIOPHARMA INC (NEXS)Approved
NEXUS BIOPHARMA INC (NEXS)Approved
Clinical Trials (7)

Does Topical Use of Tranexamic Acid During a Cesarean Delivery Reduce Intra-surgical Bleeding? A Randomized ,Multi-center Trial

NCT07362992·Early Phase 1
Recruiting

Primary endpoint: Uterine closure time (minutes)

InterventionalRandomizedopen112 targetStarted 2026-07Completion 2028-124 sites · IsraelWolfson Medical Center

Postoperative Continuous Intravenous Tranexamic Acid Infusion to Reduce Blood Loss in Non-Ambulatory Children With Cerebral Palsy Following Bilateral Bony Hip Reconstructive Surgery: A Phase III Parallel-Group Randomised Placebo-Controlled Trial

NCT07672158·Phase 3·GHRS
Not yet recruiting

Primary endpoint: Mean change between treatment arms in postoperative haemoglobin mass loss, measured on postoperative day 5 or day of discharge (whichever is earlier) and estimated using the HAEmoglobin Mass loss DuRing the periOperative Period (HAEMDROP) formula

InterventionalRandomizedquadruple52 targetStarted 2026-07Completion 2029-041 site · AustraliaMurdoch Childrens Research Institute

A Comparison Between the Efficacy of Tranexamic Acid and Adrenaline to Control Endobronchial Bleeding - A Randomized Controlled Trial

Completed

Primary endpoint: Immediate Hemostasis (Bleeding Cessation)

InterventionalRandomizedsingle76 enrolledStarted 2022-01Completion 2023-011 site · PakistanSheikh Zayed Federal Postgraduate Medical Institute

Topical Application of Tranexamic Acid (CYKLOKAPRON®) to Reduce Blood Loss During Spine Surgery

NCT02314988·Phase 2/Phase 3
Recruiting

Primary endpoint: Maximal drop in systemic hemoglobin concentration during the postoperative period

InterventionalRandomizedtriple252 targetStarted 2020-06Completion 2027-074 sites · United StatesColumbia University

Novel Strategies to Combat Post-Traumatic Osteoarthritis (PTOA):The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients

NCT03552705·Phase 2
Recruiting

Primary endpoint: Synovial fluid IL-1

InterventionalRandomizedquadruple50 targetStarted 2019-08Completion 2027-011 site · United StatesStanford University

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Recruiting

Primary endpoint: M/P ratio

Observational1,600 targetStarted 2018-10Completion 2027-0722 sites · Canada, United StatesDuke University

A Double-blind, Randomised Controlled Trial Evaluating the Safety and Efficacy of Antifibrinolytics (Tranexamic Acid) in Patients With Haematological Malignancies With Severe Thrombocytopenia

NCT03136445·Phase 3
Completed

Primary endpoint: The Proportion of Patients Who Die or Have Bleeding of WHO Grade 2 or Above by WHO Criteria During the First 30 Days From the First Dose of Trial Treatment, or Planned First Dose for Those Participants Who do Not Receive Treatment.

InterventionalRandomizedquadruple616 enrolledStarted 2015-06Completion 2022-0627 sites · Australia, United KingdomNHS Blood and Transplant
FDA Decisions1 records
Approval1 INDICATIONS AND USAGE Tranexamic Acid in Sodium Chloride Injection is indicated in patients with hemophilia for short-term use (two to eight days) to reduce or prevent hemorrhage and reduce the need for replacement therapy during and following tooth extraction. Tranexamic Acid in Sodium Chloride Injection is an antifibrinolytic indicated in patients with hemophilia for short-term use (two to eight days) to reduce or prevent hemorrhage and reduce the need for replacement therapy during and foll(NEXS)FDA ↗
ANDA216877UNKNOWNStandardIntravenousSolution

Frequently asked questions

Who is developing tranexamic acid?

tranexamic acid is being developed by NEXUS BIOPHARMA INC.

How many clinical trials involve tranexamic acid?

BioSniper tracks 7 clinical trials involving tranexamic acid.

What is tranexamic acid's latest FDA decision?

The most recent tracked FDA decision for tranexamic acid is Approval for 1 INDICATIONS AND USAGE Tranexamic Acid in Sodium Chloride Injection is indicated in patients with hemophilia for short-term use (two to eight days) to reduce or prevent hemorrhage and reduce the need for replacement therapy during and following tooth extraction. Tranexamic Acid in Sodium Chloride Injection is an antifibrinolytic indicated in patients with hemophilia for short-term use (two to eight days) to reduce or prevent hemorrhage and reduce the need for replacement therapy during and foll, dated April 16, 2024.