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tivozanib

Generic: TIVOZANIB HYDROCHLORIDE·Brand: FOTIVDA, Fotivda

tivozanib: 6 clinical trials tracked.

tivozanib evidence translation

What we can confirm

6 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about tivozanib, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence8 indications · 1 study sponsors
Clinical Trial Registry Records (6)

A Phase 2 Study of RP2 With Tivozanib in Patients With Metastatic Renal Carcinoma After Progression to Immunotherapy

NCT07218692Registry updated 2025-10-20·Phase 2
Not yet recruiting

Primary endpoint: Objective response rate

Interventionalopen35 targetStarted 2026-08Completion 2027-082 sites · United StatesCity of Hope Medical Center

Short TeRm Intensified Pembrolizumab (KEytruda) and Tivozanib for High-Risk Renal Cell Carcinoma - STRIKE

NCT06661720Registry updated 2026-09-02·Phase 3
Recruiting

Primary endpoint: Disease-free survival (DFS)

InterventionalRandomizedopen1,040 targetStarted 2025-03Completion 2037-1150 sites · United StatesAlliance for Clinical Trials in Oncology

Phase 2 Study of Combination Tivozanib and Nivolumab in Advanced Non-Clear Cell Renal Cell Carcinoma

NCT06053658Registry updated 2026-05-20·Phase 2
Recruiting

Primary endpoint: Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0

Interventionalopen48 targetStarted 2024-01Completion 2028-116 sites · United StatesM.D. Anderson Cancer Center

Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types

NCT05000294Registry updated 2026-06-05·Phase 1/Phase 2
Recruiting

Primary endpoint: Objective response rate (ORR)

Interventionalopen29 targetStarted 2021-12Completion 2027-061 site · United StatesUniversity of Florida

TiNivo-2: A Phase 3, Randomized, Controlled, Multicenter, Open-label Study to Compare Tivozanib in Combination With Nivolumab to Tivozanib Monotherapy in Subjects With Renal Cell Carcinoma Who Have Progressed Following One or Two Lines of Therapy Where One Line Has an Immune Checkpoint Inhibitor

NCT04987203Registry updated 2026-05-08·Phase 3·AVEO
Completed

Primary endpoint: Progression free survival

InterventionalRandomizedopen343 enrolledStarted 2021-09Completion 2026-0150 sites · Argentina, Australia, Belgium, United StatesAVEO Pharmaceuticals, Inc.

Phase 2 Combination Trial of Tivozanib and Enzalutamide in Men With Advanced Prostate Cancer

NCT01885949Registry updated 2025-07-16·Phase 2
Terminated

Primary endpoint: Progression Free Survival

Interventionalopen5 targetStarted 2013-09Completion 2024-051 site · United StatesMassachusetts General Hospital