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tildacerfont

Generic: Tildacerfont

tildacerfont: developed by 1 company · 4 clinical trials tracked.

tildacerfont evidence translation

What we can confirm

What it means

Source-backed records connect tildacerfont to SPRB; that link alone does not prove the drug works.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

How could tildacerfont → SPRB affect its developer, and what evidence supports the link?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 0 study sponsors

Related indications

Polycystic Ovary Syndrome; Congenital Adrenal HyperplasiaCongenital Adrenal Hyperplasia

Study sponsors

No additional listed-company sponsor is linked.

Development Pipeline (1)
CompanyPhase
SPRUCE BIOSCIENCES, INC. (SPRB)
Polycystic Ovary Syndrome; Congenital Adrenal Hyperplasia
Phase 2
Clinical Trials (4)

A Randomized, Placebo-Controlled, Dose Escalation Study to Evaluate the Safety and Efficacy of Tildacerfont in Adult Subjects With Polycystic Ovary Syndrome (PCOS) and Elevated Adrenal Androgens

NCT05370521·Phase 2·SPRB
Terminated

Primary endpoint: Change in DHEAS

InterventionalRandomizedtriple27 targetStarted 2022-05Completion 2023-0821 sites · United StatesSpruce Biosciences

A Phase 2 Study to Evaluate the Safety, Efficacy and Pharmacokinetics of SPR001 (Tildacerfont) in Children Aged 2 to 17 Years With Congenital Adrenal Hyperplasia (CAH)

NCT05128942·Phase 2·SPRB
Terminated

Primary endpoint: Number of Participants With Treatment-emergent Adverse Event (TEAE) as Assessed by Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0

Interventionalopen67 targetStarted 2021-12Completion 2025-0113 sites · United StatesSpruce Biosciences

A 3-Month Phase 2 Study to Evaluate the Safety and Efficacy of SPR001 in Subjects With Classic Congenital Adrenal Hyperplasia

NCT03687242·Phase 2·SPRB
Completed

Primary endpoint: The Incidence of Treatment-emergent Adverse Events (Safety and Tolerability) in Subjects With CAH

Interventionalopen11 enrolledStarted 2018-09Completion 2019-088 sites · United StatesSpruce Biosciences

A Phase 2, Multiple-Dose, Dose-Escalation Study to Evaluate the Safety and Efficacy of SPR001 in Adults With Classic Congenital Adrenal Hyperplasia (CAH)

NCT03257462·Phase 2·SPRB
Completed

Primary endpoint: Safety of SPR001 in Patients With CAH

Interventionalopen24 enrolledStarted 2017-07Completion 2019-039 sites · United StatesSpruce Biosciences

Frequently asked questions

Who is developing tildacerfont?

tildacerfont is being developed by SPRUCE BIOSCIENCES, INC..

How many clinical trials involve tildacerfont?

BioSniper tracks 4 clinical trials involving tildacerfont.