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tecovirimat

Generic: TECOVIRIMAT·Brand: TPOXX, Tpoxx

tecovirimat: 4 clinical trials tracked.

tecovirimat evidence translation

What we can confirm

4 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about tecovirimat, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence1 indications · 1 study sponsors

Related indications

Clinical Trial Registry Records (4)

A Randomized, Placebo-Controlled, Double-Blinded Trial of the Safety and Efficacy of Tecovirimat for the Treatment of Human Mpox Virus Disease

NCT05534984Registry updated 2026-06-23·Phase 3
Terminated

Primary endpoint: Cumulative Proportion With Clinical Resolution by Day 29

InterventionalRandomizeddouble719 targetStarted 2022-09Completion 2025-0250 sites · Argentina, Brazil, Mexico, Peru…National Institute of Allergy and Infectious Diseases (NIAID)

A Post-Marketing Open-Label, 5 Period Crossover, Drug-Drug Interaction Study of Orally Adminstered TPOXX When Co-administered With 4 Different Phosphate Binders in Healthy Subjects

NCT04485039Registry updated 2026-09-11·Phase 4·SIGA
Completed

Primary endpoint: AUC0-inf

InterventionalRandomizedopen44 enrolledStarted 2022-06Completion 2023-041 site · United StatesSIGA Technologies

A Phase 1, Open-Label (JYNNEOS®), Double-Blind (TPOXX® And Placebo), Multicenter, Randomized, Placebo-Controlled, Drug-Vaccine Interaction Study To Evaluate the Impact of TPOXX on JYNNEOS Immunogenicity

NCT04957485Registry updated 2026-09-14·Phase 2·SIGA
Active, not recruiting

Primary endpoint: Adverse Events

InterventionalRandomizeddouble100 enrolledStarted 2022-04Completion 2027-012 sites · United StatesSIGA Technologies

An Expanded Double-Blind, Placebo Controlled, Multicenter Trial to Assess the Safety, Tolerability, and Pharmacokinetics of the Anti Orthopoxvirus Compound Tecovirimat When Administered Orally for 14 Days in Subjects

NCT02474589Registry updated 2026-09-11·Phase 3·SIGA
Completed

Primary endpoint: To Determine the Number of Participants With Adverse Events

InterventionalRandomizeddouble449 enrolledStarted 2015-06Completion 2016-0811 sites · United StatesSIGA Technologies