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tapinarof

Generic: TAPINAROF·Brand: VTAMA, Vtama

tapinarof: 6 clinical trials tracked.

tapinarof evidence translation

What we can confirm

6 tracked trials

No verified listed company relationship

What it means

AI will separate confirmed drug evidence from unknown company context.

What to watch

Watch trial status, endpoints, and the next source-backed update.
BioSniper AIPage evidence connected

Prepared research question

What is verified about tapinarof, and what remains unknown?

Run cited research

Traceable citations · Unknowns marked

See linked entities and source evidence2 indications · 0 study sponsors

Study sponsors

No additional listed-company sponsor is linked.

Clinical Trial Registry Records (6)

A Randomized, Double-Blind, Vehicle-Controlled (Period 1) and Open-Label (Period 2) Phase 3 Study to Investigate the Safety and Efficacy of Tapinarof Cream, 1% in Pediatric Participants Ages 3 Months to < 24 Months With Atopic Dermatitis

NCT07265479Registry updated 2026-10-05·Phase 3
Suspended

Primary endpoint: Percentage of participants who have a validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD) score of clear or almost clear (0 or 1) and a minimum 2-grade Improvement from Baseline to Week 8

InterventionalRandomizedquadruple187 enrolledStarted 2025-12Completion 2027-0846 sites · Canada, United StatesOrganon and Co

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multiple-Site, Clinical Study to Evaluate the Therapeutic Equivalence of Tapinarof Cream 1% (Teva Pharmaceuticals, Inc.) With VTAMA® Tapinarof (Tapinarof) Cream 1% (Dermavant Sciences, Inc.) in Adult Patients With Plaque Psoriasis

NCT06742957Registry updated 2025-12-17·Phase 3
Completed

Primary endpoint: Primary change in the Physician Global Assessment (PGA)

InterventionalRandomizedquadruple560 enrolledStarted 2024-12Completion 2025-1126 sites · United StatesTeva Pharmaceuticals USA

An Open-label, Phase II Study to Evaluate the Clinical Efficacy and Safety of Tapinarof for Adult Patients With Palmoplantar Keratoderma

NCT06561321Registry updated 2026-06-23·Phase 2
Active, not recruiting

Primary endpoint: Physician's Global Assessment (PGA)

Interventionalopen6 targetStarted 2024-10Completion 2027-121 site · United StatesIndiana University

A Phase 3 Study of Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects

NCT05172726Registry updated 2026-04-17·Phase 3
Active, not recruiting

Primary endpoint: Adverse Events (AEs) and Serious Adverse Events (SAEs)

Interventionalopen58 targetStarted 2021-12Completion 2026-1019 sites · Canada, United StatesOrganon and Co

A Phase 3 Efficacy and Safety Study of Tapinarof for the Treatment of Plaque Psoriasis in Adults

NCT03983980Registry updated 2025-06-12·Phase 3
Completed

Primary endpoint: Percent of Subjects Who Achieve a Physician Global Assessment (PGA) Score of Clear (0) or Almost Clear (1) With a Minimum 2-grade Improvement From Baseline at Week 12. Analyses Were Done Using Multiple Imputation

InterventionalRandomizedtriple515 enrolledStarted 2019-06Completion 2020-0550 sites · Canada, United StatesOrganon and Co

A Phase 3 Efficacy and Safety Study of Tapinarof for the Treatment of Plaque Psoriasis in Adults

NCT03956355Registry updated 2025-06-12·Phase 3
Completed

Primary endpoint: Percent of Subjects Who Achieve a Physician Global Assessment (PGA) Score of Clear (0) or Almost Clear (1) With a Minimum 2-grade Improvement From Baseline at Week 12. Analyses Were Done Using Multiple Imputation

InterventionalRandomizedquadruple510 enrolledStarted 2019-05Completion 2020-0550 sites · Canada, United StatesOrganon and Co